CAS 2920000-23-1

LZ-007

CAS: 2920000-23-1

LZ-007 is an agonist of the Farnesoid X receptor (FXR), with an EC50 of 51 nM as determined by TR-FRET assay, and an EC50 of 76 nM in HepG2 cells. It exhibits favorable pharmacokinetic properties in SD rats and can improve metabolic dysfunction-associated steatohepatitis induced by high-fat diets and CCl4 in mice.

Fórmula: C₂₇H₂₉F₃N₂O₅

Cor e Forma: Solid

Peso molecular: 518.53

Ref: TM-T203062