CAS 2921-57-5

Succinato de metilprednisolona

Descrição:

Succinato de metilprednisolona é um corticosteroide sintético com propriedades anti-inflamatórias e imunossupressoras, comumente utilizado no tratamento de várias condições, como alergias, distúrbios autoimunes e certos tipos de câncer. É um derivado da metilprednisolona, que é uma forma modificada do hormônio esteroide cortisol. A substância é caracterizada por sua capacidade de inibir a liberação de mediadores inflamatórios e modular as respostas imunológicas. Succinato de metilprednisolona é tipicamente administrado por injeção e é conhecido por seu rápido início de ação. Sua estrutura química inclui um éster succinato, que melhora sua solubilidade e biodisponibilidade. O composto é geralmente bem tolerado, mas os efeitos colaterais potenciais podem incluir aumento do risco de infecções, distúrbios gastrointestinais e alterações no metabolismo da glicose. Assim como outros corticosteroides, o uso a longo prazo requer monitoramento cuidadoso devido a possíveis efeitos adversos em vários sistemas orgânicos. No geral, Succinato de metilprednisolona é um agente terapêutico valioso no manejo de condições inflamatórias e autoimunes.

Fórmula: C₂₆H₃₄O₈

InChI: InChI=1S/C26H34O8/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31)/t14-,16-,17-,19-,23+,24-,25-,26-/m0/s1

Chave InChI: InChIKey=IMBXEJJVJRTNOW-XYMSELFBSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(COC(CCC(O)=O)=O)=O)O)[H]

Sinónimos:

• (6α,11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
• 11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-(Hydrogen Succinate)
• 4-{[(6Alpha,11Beta)-11,17-Dihydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl]Oxy}-4-Oxobutanoic Acid
• 6-Methylprednisolone hemisuccinate
• 6α-Methylprednisolone 21-succinate
• 6α-Methylprednisolone hemisuccinate
• Methylprednisolone 21-hemisuccinate
• Methylprednisolone succinate
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(H succinate)
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(hydrogen succinate)
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-succinate

Methylprednisolone Hydrogen Succinate

CAS: 2921-57-5

Cor e Forma: Neat

Ref: 61-FOR1515.00

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PERFORMANCE TEST CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PERFORMANCE TEST CRS

Cor e Forma: Powder

Ref: 41-M1755220

METHYLPREDNISOLONE HYDROGEN SUCCINATE CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE CRS

Fórmula: C₂₆H₃₄O₈

Cor e Forma: Powder

Peso molecular: 474.5434

Ref: 41-M1755200

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PEAK IDENTIFICATION CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PEAK IDENTIFICATION CRS

Fórmula: C₂₆H₃₄O₈

Cor e Forma: Powder

Peso molecular: 474.5434

Ref: 41-Y0001759

Methylprednisolone Hemisuccinate

CAS: 2921-57-5

Adrenal cortical hormones and their derivatives nesoi

Fórmula: C₂₆H₃₄O₈

Cor e Forma: White Off-White Powder

Peso molecular: 474.22537

Ref: 45-1437009

Methylprednisolone 21-Hemisuccinate (Methylprednisolone Hydrogen Succinate)

CAS: 2921-57-5

Fórmula: C₂₆H₃₄O₈

Cor e Forma: White To Off-White Solid

Peso molecular: 474.55

Ref: 4Z-P-11138

Methylprednisolone succinate

CAS: 2921-57-5

Methylprednisolone succinate

Pureza: ≥98%

Peso molecular: 474.54g/mol

Ref: 54-BUP11730

Methylprednisolone Hydrogen Succinate

Produto Controlado

CAS: 2921-57-5

Fórmula: C₂₆H₃₄O₈

Cor e Forma: Neat

Peso molecular: 474.54

Ref: 86-MM1515.00

Methylprednisolone succinate

CAS: 2921-57-5

Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.

Fórmula: C₂₆H₃₄O₈

Pureza: 98.41% - 99.82%

Cor e Forma: White Or Almost-White Solid Powder

Peso molecular: 474.54

Ref: TM-T22367

Methylprednisolone Succinate RS

CAS: 2921-57-5

Cor e Forma: White Solid Crystalline Powder

Ref: 2K-1165000021

Methylprednisolone 21-Hemisuccinate

CAS: 2921-57-5

Fórmula: C₂₆H₃₄O₈

Peso molecular: 474.55

Ref: ST-EA-CP-M14014

6a-Methylprednisolone 21-Hemisuccinate

Produto Controlado

CAS: 2921-57-5

Applications 6α-Methylprednisolone 21-Hemisuccinate is a derivative of methylprednisolone (M325934), a glucocorticoid and a anti-inflammatory drug used to treat central nervous system disorders such as multiple sclerosis. 6α-Methylprednisolone 21-Hemisuccinate was examined for potential therapeutic efficacy in a model of neuroinflammation in rats with acute autoimmune encephalomyelitis.
References Gaillard, P.J., et al.: J. Controlled. Release., 164, 364 (2012);

Fórmula: C₂₆H₃₄O₈

Cor e Forma: White To Off-White

Peso molecular: 474.54

Ref: TR-M331195

Methylprednisolone hemisuccinate

Produto Controlado

CAS: 2921-57-5

Meghylprednisolone hemisuccinate is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the group of pharmacological agents. It is used for pain relief in cases of inflammatory bowel disease, and has been shown to be effective against human immunoglobulin A (IgA) nephropathy. Meghylprednisolone hemisuccinate inhibits prostaglandin synthesis by binding to the enzyme cyclooxygenase and blocking the conversion of arachidonic acid to prostaglandins. This drug also blocks the production of leukotrienes, which are mediators of inflammation and tissue injury. Meghylprednisolone hemisuccinate has been shown to be less toxic than methylprednisolone sodium succinate in rats when given at low doses orally, although it has not been studied in humans.

Fórmula: C₂₆H₃₄O₈

Pureza: Min. 95%

Peso molecular: 474.54 g/mol

Ref: 3D-FM39645