CAS 29428-50-0

Acetato de metila 1,2,3,4-tetrahidro-2,4-dioxo-1-β-D-ribofuranosil-5-pirimidina

Descrição:

Acetato de metila 1,2,3,4-tetrahidro-2,4-dioxo-1-β-D-ribofuranosil-5-pirimidina, com o número CAS 29428-50-0, é um composto químico que apresenta uma estrutura complexa caracterizada por um anel de pirimidina e um grupo ribofuranosila. Este composto é notável por sua potencial atividade biológica, particularmente no contexto de análogos de nucleosídeos, que podem influenciar o metabolismo de ácidos nucleicos. A presença dos grupos tetraidro e dioxo contribui para sua reatividade e estabilidade sob várias condições. Tipicamente, tais compostos podem exibir propriedades como solubilidade em solventes polares, e podem participar de ligações de hidrogênio devido à presença de grupos funcionais hidroxila e carbonila. A funcionalidade do éster metílico sugere que pode sofrer hidrólise para liberar o ácido correspondente, o que pode impactar ainda mais suas interações biológicas. No geral, as características estruturais deste composto o posicionam como um candidato para pesquisa em química medicinal, particularmente no desenvolvimento de agentes antivirais ou anticancerígenos.

Fórmula: C₁₂H₁₆N₂O₈

InChI: InChI=1/C12H16N2O8/c1-21-7(16)2-5-3-14(12(20)13-10(5)19)11-9(18)8(17)6(4-15)22-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,20)/t6-,8-,9-,11-/m1/s1

Chave InChI: InChIKey=YIZYCHKPHCPKHZ-PNHWDRBUSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(CC(OC)=O)=C2

Sinónimos:

• 5-Carboxymethyluridine methyl ester
• 5-Methoxycarbonyl methyl uridine
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, methyl ester
• Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-5-pyrimidineacetate
• Uridine, 5-(2-Methoxy-2-Oxoethyl)-
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester
• 5-(2-Methoxy-2-oxoethyl)uridine
• Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-beta-D-ribofur anosyl-, methyl ester
• 5-(Methoxycarbonyl) methyluridine (MCM5U
• 5-<(methylcarboxy)methyl>uridine
• 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyrimidineacetic Acid Methyl Ester, 5-(Methoxy carbonyl)-methyluridine, Uridine 5-acetic acid methyl ester
• 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyriMidineacetic Acid Methyl Ester
• 5-(Methoxycarbonyl) methyluridine (MCM5U),Uridine 5-acetic acid methyl ester, RNA mCm5U

5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester

CAS: 29428-50-0

Fórmula: C₁₂H₁₆N₂O₈

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 316.2640

Ref: IN-DA002YCW

5-(Methoxycarbonyl)methyluridine

CAS: 29428-50-0

5-(Methoxycarbonyl)methyluridine

Pureza: ≥98%

Peso molecular: 316.26g/mol

Ref: 54-BUP20284

5-(Methoxycarbonyl)methyluridine

CAS: 29428-50-0

5-(Methoxycarbonyl)methyluridine is an important modifying nucleotide in tRNAs, and the lack of the mcm5U modification leads to increased protein aggregation.

Fórmula: C₁₂H₁₆N₂O₈

Pureza: 99.71%

Cor e Forma: Solid

Peso molecular: 316.26

Ref: TM-TNU0040

5-Methoxycarbonyl Methyl Uridine

Produto Controlado

CAS: 29428-50-0

Applications 5-Methoxycarbonyl methyl uridine is a nucleoside constituent of yeast transfer RNA. 5-Methoxycarbonyl methyl uridine is also a derivative of 5-carboxymethyluridine, a carboxyl-containing nucleoside that was isolated from transfer RNA of Baker’s Yeast.
References Gray, M. & Lane, B.: Biochemistry, 7, 3441 (1968); Tumaitis, T. & Lane, B.: BBA-Nuc. Acid. Prot. Synth., 224, 391 (1970)

Fórmula: C₁₂H₁₆N₂O₈

Cor e Forma: Neat

Peso molecular: 316.26

Ref: TR-M261615

5-Methoxycarbonylmethyluridine

CAS: 29428-50-0

5-Methoxycarbonylmethyluridine is a nucleoside that is a precursor in the synthesis of other nucleotides. It has been shown to have potential as a biomarker for various diseases, such as metabolic disorders and hepatic steatosis. 5-Methoxycarbonylmethyluridine also inhibits the activity of methyltransferases, which are enzymes that catalyze the transfer of methyl groups from S-adenosylmethionine to substrates. It is also used as a model system for polymerase chain reaction in cancer research, because it has been shown to inhibit DNA replication by blocking the incorporation of uracil into DNA.
5-Methoxycarbonylmethyluridine has been found at high levels in fetal bovine serum and eukaryotic cells, but not in prokaryotes or cancerous tissues.

Fórmula: C₁₂H₁₆N₂O₈

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 316.26 g/mol

Ref: 3D-NM45525