CAS 29457-07-6

Ticarcilina dissódica

Descrição:

Ticarcilina dissódica é um antibiótico penicilínico semissintético que é usado principalmente para tratar infecções causadas por bactérias Gram-negativas suscetíveis. É caracterizado por sua atividade de amplo espectro, particularmente contra Pseudomonas aeruginosa e outras Enterobacteriaceae. O composto é um sal dissódico de ticarcilina, que melhora sua solubilidade em soluções aquosas, tornando-o adequado para administração intravenosa. A ticarcilina atua inibindo a síntese da parede celular bacteriana, levando à lise celular e morte. Muitas vezes é usada em combinação com outros antibióticos, como o ácido clavulânico, para superar os mecanismos de resistência. A substância é tipicamente administrada em um ambiente clínico, e sua farmacocinética inclui rápida distribuição nos tecidos do corpo, com excreção renal sendo a principal via de eliminação. Efeitos colaterais comuns podem incluir reações alérgicas, distúrbios gastrointestinais e alterações na coagulação sanguínea. Assim como com todos os antibióticos, testes de suscetibilidade apropriados são recomendados para garantir a eficácia contra patógenos específicos.

Fórmula: C₁₅H₁₆N₂O₆S₂·2Na

InChI: InChI=1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/t7-,8-,9+,12-;;/m1../s1

Chave InChI: InChIKey=IPRJTUDVZGEREZ-QBGWIPKPSA-N

SMILES: N(C([C@H](C(O)=O)C=1C=CSC1)=O)[C@H]2[C@@]3(N([C@@H](C(O)=O)C(C)(C)S3)C2=O)[H].[Na]

Sinónimos:

• 3-Thiophenemalonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-, disodium salt, <span class="text-smallcaps">D</span>-(-)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-[2α,5α,6β(S*)]]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:2), (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-, disodium salt, (2S,5R,6R)-
• 6-<span class="text-smallcaps">D</span>(-)-(α-Carboxy-3-thienylacetamido)penicillanic acid disodium salt
• 6-<span class="text-smallcaps">D</span>-(-)-α-Carboxy-3-thienylmethylacetamido penicillanic acid
• Ab 2288
• Brl 2288
• Disodium ticarcillin
• Monapen
• Ticar
• Ticarcillin Disodium
• Ticarcillin disodium salt
• Ticarcillin sodium
• Ticarcillin sodium salt
• Ticarpen
• disodium (2R,5R,6R)-6-{[carboxylato(thiophen-3-yl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• disodium (2S,5R,6R)-6-{[(2R)-2-carboxylato-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• α-Carboxy-3-thienylmethylpenicillin disodium salt
• 3-Thiophenemalonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-, disodium salt, D-(-)-

Ticarcillin sodium

CAS: 29457-07-6

Ticarcillin sodium

Pureza: ≥95%

Peso molecular: 430.41g/mol

Ref: 54-BUP16405

Ticarcillin sodium

CAS: 29457-07-6

Ticarcillin sodium: a semisynthetic, broad-spectrum antibiotic effective against various aerobic and anaerobic bacteria.

Fórmula: C₁₅H₁₆N₂O₆S₂·2Na

Pureza: 99.09%

Cor e Forma: Solid

Peso molecular: 430.41

Ref: TM-T6706

Ticarcillin Disodium Salt (Contain 10% Methanol)

Produto Controlado

CAS: 29457-07-6

Stability Hygroscopic
Applications The disodium salt of Ticarcillin, a carboxypenicillin belonging to the beta-lactam class of antibiotics. Ticarcillin is an injectable antibiotic used in the treatment of infections caused by gram-negative bacteria, particularly Pseudomonas aeruginosa.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Paisley, J.W. et al.: Antimicrob. Agents Chemother., 14, 224 (1978); Fass, R.J. et al.: Rev. Infect. Dis., 2, 841 (1980); Husson, M.O. et al.: Drugs Exp. Clin. Res., 9, 843 (1983);

Fórmula: C₁₅H₁₄N₂O₆S₂·2Na

Cor e Forma: Neat

Peso molecular: 428.39

Ref: TR-T437901

Ticarcillin disodium

CAS: 29457-07-6

Ticarcillin is a bactericidal antibiotic that is used to treat many types of infections caused by gram-positive bacteria, such as Streptococcus pneumoniae, Enterococcus faecalis and Enterococcus faecium. Ticarcillin has been shown to be effective against antibiotic-resistant strains of bacteria, including multidrug efflux pumps. This drug also has been shown to inhibit the growth of gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa. Ticarcillin is used in combination with clavulanic acid for the treatment of infections caused by beta-lactamase producing organisms. It is also used in wastewater treatment to inhibit the growth of gram-negative bacteria that are resistant to other antibiotics. Ticarcillin can interfere with other medications by inhibiting their metabolism through cytochrome P450 enzymes or through competition for protein binding sites.

Fórmula: C₁₅H₁₆N₂Na₂O₆S₂

Pureza: Min. 80.0 Area-%

Cor e Forma: White Powder

Peso molecular: 430.41 g/mol

Ref: 3D-FC75007

Ticarcillin Disodium Salt-13C3 (Contain 10% Methanol)

Produto Controlado

CAS: 29457-07-6

Fórmula: C₃C₁₂H₁₄N₂Na₂O₆S₂

Cor e Forma: Neat

Peso molecular: 431.369

Ref: TR-T437902