CAS 29678-81-7

Ácido (R)-2-hidroxi-4-fenilbutírico

Descrição:

Ácido (R)-2-hidroxi-4-fenilbutírico, também conhecido como (R)-HPBA, é um composto quiral caracterizado por seus grupos funcionais hidroxila e ácido carboxílico. Apresenta uma estrutura de ácido butírico com um grupo fenila ligado ao quarto carbono, contribuindo para suas propriedades únicas. Este composto é tipicamente um sólido branco a off-white à temperatura ambiente e é solúvel em solventes polares como água e álcoois, devido à presença dos grupos hidroxila e ácido carboxílico. (R)-HPBA é de interesse na pesquisa farmacêutica, particularmente por suas potenciais aplicações terapêuticas, incluindo efeitos anti-inflamatórios e analgésicos. A quiralidade da molécula é significativa, pois o enantiômero (R) pode exibir atividade biológica diferente em comparação com seu contraparte (S). Sua síntese muitas vezes envolve técnicas de síntese assimétrica para garantir a estereoquímica desejada. Além disso, (R)-HPBA pode servir como um bloco de construção na síntese orgânica, facilitando o desenvolvimento de moléculas mais complexas na química medicinal.

Fórmula: C₁₀H₁₂O₃

InChI: InChI=1/C10H12O3/c11-9(10(12)13)7-6-8-4-2-1-3-5-8/h1-5,9,11H,6-7H2,(H,12,13)/t9-/m1/s1

Chave InChI: InChIKey=JNJCEALGCZSIGB-SECBINFHSA-N

SMILES: C(C[C@H](C(O)=O)O)C1=CC=CC=C1

Sinónimos:

• (2R)-2-hydroxy-4-phenylbutanoic acid
• (R)-2-Hydroxy-4-Phenyl Butyric Acid
• (R)-2-Hydroxy-4-phenylbutanoic Acid
• (r)-2-Hydroxy-4-phenylbutyricacid
• (αR)-α-Hydroxybenzenebutanoic acid
• <span class="text-smallcaps">D</span>-(-)-Benzyllactic acid
• Benzenebutanoic acid, α-hydroxy-, (R)-
• Benzenebutanoic acid, α-hydroxy-, (αR)-
• Butyric acid, 2-hydroxy-4-phenyl-, <span class="text-smallcaps">D</span>-(-)-
• Butyric acid, 2-hydroxy-4-phenyl-, D-(-)-
• D-(-)-Benzyllactic acid
• R(-)-2-HYDROXY-4-PHENYL-BUTYIC ACID
• (R)-HPBA
• (2R)-2-Hydroxy-4-phenylbutyric acid
• 2-hydroxy-4-phenylbutanoic acid2-hydroxy-4-phenylbutyric aci
• (R)-2-Hydroxy-4-pheylbutanoic Acid
• (R)-(-)-2-HYDROXY-4-PHENYLBUTYRIC ACID
• (R)-2-HYDROXY-4-PHENYLBUTYRIC ACID

Benzenebutanoic acid, α-hydroxy-, (αR)-

CAS: 29678-81-7

Fórmula: C₁₀H₁₂O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 180.2005

Ref: IN-DA002Z30

(R)-(-)-2-Hydroxy-4-phenylbutyric acid

CAS: 29678-81-7

(R)-(-)-2-Hydroxy-4-phenylbutyric acid

Pureza: 98%

Peso molecular: 180.20g/mol

Ref: 54-OR307154

(R)-2-Hydroxy-4-phenylbutyric Acid

CAS: 29678-81-7

Fórmula: C₁₀H₁₂O₃

Pureza: >97.0%(GC)(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 180.20

Ref: 3B-H1338

(R)-2-Hydroxy-4-phenylbutyric acid

CAS: 29678-81-7

Fórmula: C₁₀H₁₂O₃

Pureza: 98%

Cor e Forma: Solid, White powder

Peso molecular: 180.203

Ref: 10-F011769

(R)-2-Hydroxy-4-phenylbutanoic acid

CAS: 29678-81-7

(R)-2-Hydroxy-4-phenylbutanoic acid is an ester compound that is produced by the conversion of (S)-malic acid to its enantiomer. This reaction is catalyzed by a phosphoric acid esterase. The kinetic, immobilization, and transfer mechanisms have been characterized. The solubilized form of the enzyme was found to be more active than the crystalline form. Enzyme inhibitors such as hydrogen chloride and hydrochloric acid were also investigated in order to determine their effect on the reaction rate and product distribution. A structural formula for (R)-2-Hydroxy-4-phenylbutanoic acid was determined using nuclear magnetic resonance spectroscopy and mass spectrometry, revealing a dinucleotide phosphate as a possible intermediate in the synthesis pathway.

Fórmula: C₁₀H₁₂O₃

Pureza: Min. 95%

Peso molecular: 180.2 g/mol

Ref: 3D-FH140634