CAS 3034310-17-0

PROTAC GSPT1 degrader-1

CAS: 3034310-17-0

PROTAC GSPT1 degrader-1 (Compound F) is a PROTAC-based degrader that effectively targets and degrades G1 to S phase transition protein 1 (GSPT1), achieving degradation rates of 95% at 1 μM and 86% at 0.1 μM. Additionally, this compound inhibits the viability of HL-60 cells with an IC50 of 9.2 nM.

Fórmula: C₃₇H₃₆ClN₇O₅

Cor e Forma: Solid

Peso molecular: 694.18

Ref: TM-T200585