CAS 3046428-94-5

VEGFR-2-IN-52

CAS: 3046428-94-5

VEGFR-2-IN-52 (compound 14d) serves as a powerful inhibitor of VEGFR-2, exhibiting an IC 50 of 191.1 nM. It effectively reduces the protein expression levels of p-VEGFR-2, MMP9, p-ERK1/2, and p-MEK1. In addition, VEGFR-2-IN-52 demonstrates cytotoxic properties by inducing apoptosis and arresting the cell cycle at the G0/G1 phase, and it enhances the levels of ROS.

Fórmula: C₂₀H₂₅ClN₄O₂S

Cor e Forma: Solid

Peso molecular: 420.96

Ref: TM-T89976