CAS 3053859-57-4

PFM046

CAS: 3053859-57-4

PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.

Fórmula: C₂₉H₄₂O₂

Cor e Forma: Solid

Peso molecular: 422.643

Ref: TM-T204254