CAS 3056-33-5

2,9-Diacetilguanina

Descrição:

2,9-Diacetilguanina é um composto químico que pertence à classe de derivados da guanina, caracterizado pela presença de dois grupos acetila ligados aos átomos de nitrogênio nas posições 2 e 9 da estrutura da guanina. Essa modificação melhora sua solubilidade e reatividade em comparação com a guanina não modificada. O composto é tipicamente um sólido cristalino branco a off-white e é solúvel em solventes polares, como água e etanol. Exibe propriedades típicas de nucleobases, incluindo a capacidade de participar em ligações de hidrogênio, o que é crucial para suas potenciais aplicações em bioquímica e biologia molecular. 2,9-Diacetilguanina é de interesse na pesquisa devido ao seu papel no estudo das interações de ácidos nucleicos e seu uso potencial na síntese de análogos de nucleosídeos. Além disso, pode exibir propriedades de fluorescência, tornando-o útil em várias técnicas analíticas. Assim como muitas substâncias químicas, o manuseio deve ser feito com cuidado, seguindo os protocolos de segurança apropriados para mitigar quaisquer riscos associados ao seu uso.

Fórmula: C₉H₉N₅O₃

InChI: InChI=1/C9H9N5O3/c1-4(15)11-9-12-7-6(8(17)13-9)10-3-14(7)5(2)16/h3H,1-2H3,(H2,11,12,13,15,17)

Chave InChI: InChIKey=GILZZWCROUGLIS-UHFFFAOYSA-N

SMILES: C(C)(=O)N1C2=C(C(=O)N=C(NC(C)=O)N2)N=C1

Sinónimos:

• 2,9-Diacetylguanine
• 2,9-Guanine Diacetate
• 2-Acetylamino-9-Acetyl-6-Hydroxy purine
• 9-Diacetylguanine
• Acetamide, N-(9-acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)-
• Diacetyl Guanine
• Diacetylguanine
• Guanine, N,9-diacetyl-
• N,9-Diacetylguanine
• N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamide
• N-(9-acetyl-6-oxo-6,9-dihydro-3H-purin-2-yl)acetamide
• N2,9-Diacetylguanine
• N2,N9-Diacetylguanine
• N²,9-Diacetylguanine
• N(sup 2),9-diacetylguanine
• N2,9-DIACETYLGUANINE [DIACETYL GUANINE]ACYCLOVIR
• N2,9-DIACETYLGUANINE (DIACETYL GUANINE)
• 2,9-DIACETYLGUANINE(DIACETYLGUANINE)
• 2-(Acetylamino)-9-acetyl-9H-purine-6(1H)-one
• 2-Acetamido-9-acetyl-6-oxopurine
• 2-(Acetylamino)-9-acetyl-1,9-dihydro-6H-purine-6-one
• 2-ACETYLAMINO-6-OXO-9-ACETYLPURINE
• (9-acetyl-6,9-dihydro-6-oxo-1h-purin-2-yl)acetamide
• 2,9-DIACETATEGUANINE

N2,9-Diacetylguanine

CAS: 3056-33-5

Fórmula: C₉H₉N₅O₃

Pureza: >95.0%(T)

Cor e Forma: White to Yellow to Orange powder to crystal

Peso molecular: 235.20

Ref: 3B-D3604

N(2),9-Diacetylguanine, 99%

CAS: 3056-33-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₉H₉N₅O₃

Pureza: 99%

Cor e Forma: White to pale cream, powder

Peso molecular: 235.20

Ref: 02-B22709

Acetamide, N-(9-acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)-

CAS: 3056-33-5

Fórmula: C₉H₉N₅O₃

Pureza: 96%

Cor e Forma: Solid

Peso molecular: 235.1995

Ref: IN-DA0030JW

Acyclovir (Aciclovir) EP Impurity L

CAS: 3056-33-5

Fórmula: C₉H₉N₅O₃

Cor e Forma: White To Off-White Solid

Peso molecular: 235.20

Ref: 4Z-A-047

N,9-Diacetylguanine

CAS: 3056-33-5

N,9-Diacetylguanine

Pureza: 98%

Peso molecular: 235.20g/mol

Ref: 54-OR1014047

N(2);9-Diacetylguanine

CAS: 3056-33-5

Fórmula: C₉H₉N₅O₃

Peso molecular: 235.20

Ref: 7W-GE7096

N2,9-Diacetylguanine

Produto Controlado

CAS: 3056-33-5

Impurity Acicclovir EP Impurity L
Applications N2,9-Diacetylguanine (Acicclovir EP Impurity L) is used to synthesize acyclic analogues of deoxyguanosine.
References Martin, J. C., et al.: J Med Chem. 26, 759 (1983)

Fórmula: C₉H₉N₅O₃

Cor e Forma: Neat

Peso molecular: 235.20

Ref: TR-D335000

Aciclovir EP Impurity L

CAS: 3056-33-5

Fórmula: C₉H₉N₅O₃

Peso molecular: 235.20

Ref: ST-EA-CP-A8012

N2,9-Diacetylguanine

CAS: 3056-33-5

N2,9-Diacetylguanine is a synthetic molecule that can be used to inhibit the replication of herpes simplex virus. It has been found to inhibit the growth of viruses in vitro by binding to the viral DNA and inhibiting viral RNA synthesis. N2,9-Diacetylguanine is also a substrate for acetylation and may undergo this reaction with acetyl coenzyme A to form N4,9-diacetylguanine. The acetylated form of guanine inhibits the virus by blocking its ability to replicate DNA. The potential mechanism for this drug's anti-viral activity includes inhibition of the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides.

Fórmula: C₉H₉N₅O₃

Pureza: Min. 95%

Cor e Forma: Off-White Powder

Peso molecular: 235.2 g/mol

Ref: 3D-FD02958

N2,9-Diacetylguanine-13C2,15N

Produto Controlado

CAS: 3056-33-5

Applications N2,9-Diacetylguanine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase.
References Kazmers, I.S., et al.: Science, 214, 1137 (1981); Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)

Fórmula: C₂C₇H₉₁₅NN₄O₃

Cor e Forma: Neat

Peso molecular: 238.178

Ref: TR-D335002

N-(9-Acetyl-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide

CAS: 3056-33-5

Fórmula: C₉H₉N₅O₃

Pureza: 96%

Cor e Forma: Liquid, No data available.

Peso molecular: 235.203

Ref: 10-F219956