CAS: 30562-34-6 - Geldanamycin

Fórmula: C₂₉H₄₀N₂O₉

InChI: InChI=1S/C29H40N2O9/c1-15-11-19-25(34)20(14-21(32)27(19)39-7)31-28(35)16(2)9-8-10-22(37-5)26(40-29(30)36)18(4)13-17(3)24(33)23(12-15)38-6/h8-10,13-15,17,22-24,26,33H,11-12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8-,16-9+,18-13+/t15-,17+,22+,23+,24-,26+/m1/s1

Chave InChI: InChIKey=QTQAWLPCGQOSGP-KSRBKZBZSA-N

SMILES: O=C(OC1C(=CC(C)C(O)C(OC)CC(C)CC=2C(=O)C(=CC(=O)C2OC)NC(=O)C(=CC=CC1OC)C)C)N

Sinónimos:

• (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
• (8S,9S,12S,13R,14S,16R)-13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
• 2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9,13-dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, 9-carbamate
• 2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-[(aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, [8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-
• 2-Azabicyclo[16.3.1]docosane, geldanamycin deriv.
• Brn 1633093
• NSC 212518
• Nsc 122750
• U-29135
• [8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-9-[(Aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione

Geldanamycin

CAS: 30562-34-6

• Fórmula: C₂₉H₄₀N₂O₉
• Pureza: >98.0%(HPLC)
• Cor e Forma: White to Yellow to Orange powder to crystal
• Peso molecular: 560.64

Geldanamycin, 98+%

CAS: 30562-34-6

Geldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). …

• Fórmula: C₂₉H₄₀N₂O₉
• Pureza: 98+%
• Cor e Forma: Powder or crystals or crystalline powder, Yellow
• Peso molecular: 560.64

Geldanamycin

CAS: 30562-34-6

• Fórmula: C₂₉H₄₀N₂O₉
• Pureza: 100.0%
• Cor e Forma: Orange amorphous solid
• Peso molecular: 560.0

Geldanamycin, Streptomyces hygroscopicus

CAS: 30562-34-6

• Pureza: >95%
• Cor e Forma: Solid
• Peso molecular: 560.644

[8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-9-[(Aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione

CAS: 30562-34-6

• Fórmula: C₂₉H₄₀N₂O₉
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 560.6359

Geldanamycin

CAS: 30562-34-6

• Fórmula: C₂₉H₄₀N₂O₉
• Pureza: ≥ 98.0%
• Cor e Forma: Yellow to orange powder
• Peso molecular: 560.64

Geldanamycin

CAS: 30562-34-6

• Fórmula: C₂₉H₄₀N₂O₉
• Peso molecular: 560.64

Geldanamycin

CAS: 30562-34-6

• Fórmula: C₂₉H₄₀N₂O₉
• Pureza: By hplc: 99.66% (Typical Value in Batch COA)
• Cor e Forma: yellow powder
• Peso molecular: 560.64g/mol

Geldanamycin

CAS: 30562-34-6

Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.

• Fórmula: C₂₉H₄₀N₂O₉
• Pureza: 98.83%
• Cor e Forma: Yellow To Orange Powder
• Peso molecular: 560.64

Geldanamycin

CAS: 30562-34-6

Applications Geldanamycin is a potent antitumor antibiotic active at nanomolar concentration against 60 cell lines.It …

• Fórmula: C₂₉H₄₀N₂O₉
• Cor e Forma: Neat
• Peso molecular: 560.64

Geldanamycin

CAS: 30562-34-6

Inhibits chaperone protein HSP90; anti-proliferative; antineoplastic

• Fórmula: C₂₉H₄₀N₂O₉
• Pureza: Min. 95%
• Cor e Forma: Yellow Powder
• Peso molecular: 560.64 g/mol

Geldanamycin (GLD), 98%

CAS: 30562-34-6

• Fórmula: C₂₉H₄₀N₂O₉
• Peso molecular: 560.64

Geldanamycin-FITC

CAS: 30562-34-6

• Fórmula: C₅₅H₆₃N₅O₁₃S
• Cor e Forma: Neat
• Peso molecular: 1034.18