CAS 306-07-0

Cloridrato de pargilina

Descrição:

Cloridrato de pargilina é um composto farmacêutico reconhecido principalmente por seu papel como inibidor da monoamina oxidase (IMAO). É comumente utilizado no tratamento de certos tipos de depressão e foi investigado por suas propriedades neuroprotetoras. A substância aparece como um pó cristalino branco a off-white e é solúvel em água, o que facilita sua administração em ambientes clínicos. A pargilina atua inibindo a enzima monoamina oxidase, aumentando assim os níveis de neurotransmissores como serotonina, norepinefrina e dopamina no cérebro, o que pode ajudar a aliviar os sintomas depressivos. Sua estrutura química inclui um anel de piridina, contribuindo para sua atividade farmacológica. Embora seja eficaz, o uso de Cloridrato de pargilina requer monitoramento cuidadoso devido a possíveis restrições dietéticas e interações com outros medicamentos, particularmente aqueles que contêm tiramina, o que pode levar a crises hipertensivas. Assim como com qualquer IMAO, os pacientes devem ser informados sobre os riscos e benefícios associados ao seu uso.

Fórmula: C₁₁H₁₄ClN

InChI: InChI=1/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

Chave InChI: InChIKey=BCXCABRDBBWWGY-UHFFFAOYSA-N

SMILES: C(N(CC#C)C)C1=CC=CC=C1.Cl

Sinónimos:

• A 19120
• Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1)
• Benzenemethanamine, N-methyl-N-2-propynyl-, hydrochloride
• Benzylamine, N-methyl-N-2-propynyl-, hydrochloride
• Eutonyl
• Eutonyl-ten
• Methylbenzylpropynylamine hydrochloride
• Mo 911
• N-Benzyl-N-methyl-2-propynylamine hydrochloride
• N-Methyl-N-(2-propynyl)benzylamine hydrochloride
• N-Methyl-N-2-propynylbenzylamine hydrochloride
• N-benzyl-N-methylprop-2-yn-1-amine
• N-benzyl-N-methylprop-2-yn-1-amine hydrochloride (1:1)
• N-methyl-N-propargylbenzylamine hydro-chloride
• NSC 43798
• Parguline HCL
• Pargyline Hcl
• n-methyl-n-2-propynyl-benzylaminhydrochloride
• PARGYLINE HYDROCHLOR
• PARGYLINE HYDROCHLORIDE MAO INHIBITOR
• N-METHYL-N-PROPARGYLBENZYLAMINE HYDROCHLORIDE
• benzylmethylpropynylaminehydrochloride
• N-methyl-N-(phenylmethyl)-2-propyn-1-amine hydrochloride
• n-benzyl-n-methyl-2-propynylaminhydrochloride
• N-Methyl-npropargylbenzeneMethanaMine HCl
• n-benzyl-n-methyl-2-propynylaminehydrochloride
• N-METHYL-N-(2-PROPYNY)BENZYLAMINE HYDROCHLORIDE
• N-benzyl-N-methylprop-2-yn-1-amine hydrochloride
• N-methyl-N-(phenylmethyl)prop-2-yn-1-amine hydrochloride
• Pargyline Hydrochloride (200 mg)
• PARGYLINE HYDROCHLORIDE USP/EP/BP
• PARGYLINE HYDROCHLORIDE
• pargylinechloride
• benzyl-methyl-propargyl-amine hydrochloride
• N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Pargyline hydrochloride,N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Pargylamine hydrochloride

Pargyline Hydrochloride

CAS: 306-07-0

Cor e Forma: Neat

Ref: 61-FOR1912.00

Pargyline, HCl

CAS: 306-07-0

Fórmula: C₁₁H₁₄ClN

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 195.6886

Ref: IN-DA0030N6

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.

Fórmula: C₁₁H₁₄ClN

Pureza: 99.41% - 99.91%

Cor e Forma: Solid

Peso molecular: 195.69

Ref: TM-T1578

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride

Pureza: ≥98%

Peso molecular: 195.69g/mol

Ref: 54-BUP17536

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 195.69g/mol

Ref: 54-OR54425

Pargyline hydrochloride

CAS: 306-07-0

Fórmula: C₁₁H₁₃N·HCl

Pureza: ≥ 98.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 195.69

Ref: 7W-GP7491

Pargyline Hydrochloride

Produto Controlado

CAS: 306-07-0

Fórmula: C₁₁H₁₃N·ClH

Cor e Forma: Neat

Peso molecular: 195.69

Ref: 86-MM1912.00

Pargyline Hydrochloride

Produto Controlado

CAS: 306-07-0

Applications Pargyline Hydrochloride acts as a monoamine oxidase (MAO) inhibitor, decreasing systolic blood pressure steadily in subjects. Antihypertensive.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fuentes, J. et al.: Eur. J. Pharm., 57, 21 (1979); Knoll, J. et al.: Tabei, R. et al.: Clin. Pharm. Ther., 11, 269 (1970);

Fórmula: C₁₁H₁₃N·ClH

Cor e Forma: Neat

Peso molecular: 195.69

Ref: TR-P193285

N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride

CAS: 306-07-0

Fórmula: C₁₁H₁₄ClN

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 195.69

Ref: 10-F336074

N-Methyl-N-propargylbenzylamine HCl

Produto Controlado

CAS: 306-07-0

N-Methyl-N-propargylbenzylamine HCl is a nonsteroidal anti-inflammatory drug that inhibits the enzyme cyclooxygenase (COX) and blocks the production of prostaglandins. This drug has low potency, although its selectivity for COX-2 makes it an attractive candidate for treatment of inflammation associated with arthritis. N-Methyl-N-propargylbenzylamine HCl also has been shown to have receptor activity on toll-like receptor 4 in human biological samples. It has been shown to decrease dopamine levels in rats, suggesting that it may be a potential treatment for Parkinson's disease. In addition, this drug was found to decrease epithelial mesenchymal transition and increase expression of p53 protein in prostate cancer cells, as well as inhibit 5HT2 receptors in rat brain tissue. This drug also increases 5HT concentrations and decreases diastolic blood pressure in humans.

Pureza: Min. 95%

Ref: 3D-FM41823