CAS 3067908-20-4

Enpp-1-IN-25

CAS: 3067908-20-4

Enpp-1-IN-25 (Compound 30) is an ENPP1 inhibitor with an IC50 of 8.05 nM and exhibits low oral bioavailability. By inhibiting cGAMP degradation, it effectively activates the intracellular STING pathway. Enpp-1-IN-25 can enhance immune cell infiltration and type I interferon response in the tumor microenvironment, thereby increasing the antitumor efficacy of anti-PD-L1 antibodies. It is applicable for research in cancer immunotherapy.

Fórmula: C₁₅H₂₁N₅O₄S

Cor e Forma: Solid

Peso molecular: 367.423

Ref: TM-T205138