CAS 3079-63-8

N-[(Fenilmetoxi)carbonil]glicil-L-alanina

Descrição:

N-[(Fenilmetoxi)carbonil]glicil-L-alanina, com o número CAS 3079-63-8, é um composto sintético que pertence à classe de derivados de aminoácidos. Esta substância apresenta uma porção de glicina ligada a um resíduo de L-alanina, com um grupo protetor de fenilmetoxicarbonila. A presença do grupo fenilmetoxi aumenta sua lipofilicidade e estabilidade, tornando-o útil em várias aplicações bioquímicas, particularmente na síntese de peptídeos e no desenvolvimento de medicamentos. O composto é caracterizado por sua capacidade de participar na formação de ligações peptídicas, que é essencial na construção de cadeias peptídicas maiores. Além disso, pode exibir atividades biológicas específicas devido aos seus componentes estruturais, potencialmente influenciando sua interação com alvos biológicos. Sua solubilidade e reatividade podem variar dependendo do solvente e das condições, o que é crucial para sua aplicação em ambientes de laboratório. No geral, N-[(Fenilmetoxi)carbonil]glicil-L-alanina serve como um intermediário valioso na síntese orgânica e na química medicinal.

Fórmula: C₁₃H₁₆N₂O₅

InChI: InChI=1S/C13H16N2O5/c1-9(12(17)18)15-11(16)7-14-13(19)20-8-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,14,19)(H,15,16)(H,17,18)/t9-/m0/s1

Chave InChI: InChIKey=CCIBGDNXMPNUHL-VIFPVBQESA-N

SMILES: C(OC(NCC(N[C@H](C(O)=O)C)=O)=O)C1=CC=CC=C1

Sinónimos:

• (2S)-2-[[2-(Phenylmethoxycarbonylamino)acetyl]amino]propanoic acid
• (Benzyloxycarbonyl)glycyl-<span class="text-smallcaps">L</span>-alanine
• <span class="text-smallcaps">L</span>-Alanine, N-[(phenylmethoxy)carbonyl]glycyl-
• <span class="text-smallcaps">L</span>-Alanine, N-[N-[(phenylmethoxy)carbonyl]glycyl]-
• Alanine, N-(N-carboxyglycyl)-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• N-(Benzyloxycarbonyl)glycyl-<span class="text-smallcaps">L</span>-alanine
• N-(Benzyloxycarbonyl)glycylalanine
• N-[(Phenylmethoxy)carbonyl]glycyl-<span class="text-smallcaps">L</span>-alanine
• N-[(benzyloxy)carbonyl]glycylalanine
• NSC 169157
• Z-Gly-Ala-OH
• L-Alanine, N-[(phenylmethoxy)carbonyl]glycyl-
• Alanine, N-(N-carboxyglycyl)-, N-benzyl ester, L-
• (Benzyloxycarbonyl)glycyl-L-alanine
• N-[(Phenylmethoxy)carbonyl]glycyl-L-alanine
• L-Alanine, N-[N-[(phenylmethoxy)carbonyl]glycyl]-
• N-CBZ-GLY-ALA
• Cbz-Gly-DL-Ala
• Z-Gly-L-Ala-OH
• N-carbobenzyloxy-Gly-Ala
• Z-L-GLYCYL-L-ALANINE
• z-gly-ala
• (S)-2-[[2-(Benzyloxycarbonylamino)-1-oxoethyl]amino]propanoic acid
• N-[N-[(Phenylmethoxy)carbonyl]glycyl]-L-alanine
• CBZ-GLY-L-ALA
• 2-[2-(phenylmethoxycarbonylamino)ethanoylamino]propanoic acid
• N-CARBOBENZOXY-GLYCYL-L-ALANINE
• N-(Benzyloxycarbonyl)-Gly-Ala-OH
• 2-[[2-(benzyloxycarbonylamino)acetyl]amino]propionic acid
• 2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoic acid
• Z-GLYCYL-L-ALANINE
• benzylcarbonylglycyloxy-L-alanine
• N-BENZYLOXYCARBONYLGLYCYL-L-ALANINE

Z-Gly-Ala-OH

CAS: 3079-63-8

Z-Gly-Ala-OH is an amide that is synthesized by the solid-phase synthesis of a protected amino acid. The amino acid sequence was determined by sequencing the product and comparing it to the amino acid composition of known glycyl-amides. The enzyme active site was found to be located on the side chain of Gly, which is a polar residue. This catalytic site is only occupied in one orientation, with Ala occupying the opposite side chain position. The yields for this reaction are very high and are not affected by changes in temperature or pH. Z-Gly-Ala-OH has a chiral center at position 3 and can exist as two enantiomers, Z-(+)-glycylalanine and its mirror image, Z-(−)-glycylalanine.

Fórmula: C₁₃H₁₆N₂O₅

Pureza: Min. 95%

Peso molecular: 280.28 g/mol

Ref: 3D-FG111462