CAS: 309913-83-5 - Talmapimod

Fórmula: C₂₇H₃₀ClFN₄O₃

InChI: InChI=1S/C27H30ClFN4O3/c1-16-13-33(17(2)12-32(16)14-18-6-8-19(29)9-7-18)26(35)21-10-20-22(25(34)27(36)30(3)4)15-31(5)24(20)11-23(21)28/h6-11,15-17H,12-14H2,1-5H3/t16-,17+/m0/s1

Chave InChI: InChIKey=ZMELOYOKMZBMRB-DLBZAZTESA-N

SMILES: O=C(C(=O)N(C)C)C1=CN(C=2C=C(Cl)C(=CC12)C(=O)N3CC(N(CC4=CC=C(F)C=C4)CC3C)C)C

Sinónimos:

• 1H-Indole-3-acetamide, 6-chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-
• 6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-alpha-oxo-1H-indole-3-acetamide
• 6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-1H-indole-3-acetamide
• Scio 469
• Scios 469

1H-Indole-3-acetamide, 6-chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-

CAS: 309913-83-5

• Fórmula: C₂₇H₃₀ClFN₄O₃
• Pureza: 98%
• Peso molecular: 513.0035

Talmapimod

CAS: 309913-83-5

Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold …

• Fórmula: C₂₇H₃₀ClFN₄O₃
• Pureza: 100% - 98%
• Cor e Forma: Solid
• Peso molecular: 513

Scio-469

CAS: 309913-83-5

• Peso molecular: 513.00g/mol

Talmapimod

CAS: 309913-83-5

• Fórmula: C₂₇H₃₀ClFN₄O₃
• Peso molecular: 513.01

Talmapimod

CAS: 309913-83-5

Inhibitor of p38 MAPK kinase

• Fórmula: C₂₇H₃₀ClFN₄O₃
• Pureza: Min. 95%
• Peso molecular: 513 g/mol

5-(2,6-Dichlorophenyl)-2-((2-fluoro-4-nitrophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one

CAS: 309913-83-5

• Fórmula: C₁₉H₉Cl₂FN₄O₃S
• Cor e Forma: Neat
• Peso molecular: 463.269

4-Iodobenzyl-2,6-dimethylpiperazine Talmapimod

CAS: 309913-83-5

• Fórmula: C₂₇H₃₀ClIN₄O₃
• Cor e Forma: Neat
• Peso molecular: 620.91