CAS 31557-15-0

((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane

Produto Controlado

CAS: 31557-15-0

Applications ((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a metabolite of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
References Nawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)

Fórmula: C₇H₁₇ClOSi

Cor e Forma: Neat

Peso molecular: 180.75

Ref: TR-C897545