CAS 32233-40-2

(3aR,4S,5R,6aS)-Hexahidro-5-hidroxi-4-(hidroximetil)-2H-ciclopenta[b]furano-2-ona

Descrição:

A substância química conhecida como (3aR,4S,5R,6aS)-Hexahidro-5-hidroxi-4-(hidroximetil)-2H-ciclopenta[b]furano-2-ona, com o número CAS 32233-40-2, é um composto bicíclico caracterizado por sua estrutura de anel fundido única. Este composto apresenta múltiplos estereocentros, que contribuem para sua configuração tridimensional específica e podem influenciar sua atividade biológica. A presença de grupos hidroxila (-OH) indica que pode exibir características polares, aumentando sua solubilidade em água e sua reatividade em várias reações químicas. O grupo furanona sugere que pode participar de reações típicas de lactonas e éteres cíclicos, tornando-o de interesse na síntese orgânica e na química medicinal. Além disso, a estereoquímica do composto pode desempenhar um papel crucial em sua interação com alvos biológicos, o que pode ser relevante para aplicações farmacológicas. No geral, as características estruturais deste composto sugerem uma utilidade potencial em vários campos, incluindo desenvolvimento de medicamentos e ciência dos materiais, embora aplicações específicas dependam de mais pesquisas e caracterizações.

Fórmula: C₈H₁₂O₄

InChI: InChI=1/C8H12O4/c9-3-5-4-1-8(11)12-7(4)2-6(5)10/h4-7,9-10H,1-3H2/t4-,5-,6-,7+/m1/s1

Chave InChI: InChIKey=VYTZWRCSPHQSFX-GBNDHIKLSA-N

SMILES: C(O)[C@@H]1[C@@]2([C@](C[C@H]1O)(OC(=O)C2)[H])[H]

Sinónimos:

• (-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
• (-)-Corey's lactone diol
• (-)-Coreydiol
• (3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
• (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, [3aR-(3aα,4α,5β,6aα)]-
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, stereoisomer
• 2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxymethyl)-,(3aR,4S,5R,6aS)-
• Lactone diol
• (-)-Corey Lactone Diol
• (1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone
• (-)-COREY DIOL (COREY LACTONE)
• (1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,
• (3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-(HYDROXYMETHYL)-2H-CYCLOPENT A[B]FURAN-2-ONE
• Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one.
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-HOCH2-2H-CYCLOPENTA(B)FURAN-2-ONE, 98%
• (-)-COREY LACTONE

(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98%

CAS: 32233-40-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₈H₁₂O₄

Pureza: 98%

Peso molecular: 172.18

Ref: 02-H56119

(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

CAS: 32233-40-2

Fórmula: C₈H₁₂O₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 172.1785

Ref: IN-DA0032AQ

(1S,5R,6S,7R)-(-)-7-Hydroxy-6-(hydroxymethyl)-2-oxabicyclo[3.3.0]octan-3-one

CAS: 32233-40-2

(1S,5R,6S,7R)-(-)-7-Hydroxy-6-(hydroxymethyl)-2-oxabicyclo[3.3.0]octan-3-one

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 172.18g/mol

Ref: 54-OR52144

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol

Pureza: ≥95%

Peso molecular: 172.18g/mol

Ref: 54-BUP18578

(-)-Corey Lactone Diol

CAS: 32233-40-2

Fórmula: C₈H₁₂O₄

Pureza: >98.0%(GC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 172.18

Ref: 3B-H1418

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol is a pharmaceutical intermediate

Fórmula: C₈H₁₂O₄

Pureza: 98%

Cor e Forma: White To Beige-Brown Cryst Powder Or Crystals

Peso molecular: 172.18

Ref: TM-T8085

(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

CAS: 32233-40-2

Fórmula: C₈H₁₂O₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 172.18

Ref: 10-F239043

(-)-Corey Lactone Diol

Produto Controlado

CAS: 32233-40-2

Applications (-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
References Gal, Z. et al.: J. Chemother., 12, 274 (2000); Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008);

Fórmula: C₈H₁₂O₄

Cor e Forma: Neat

Peso molecular: 172.18

Ref: TR-C694995

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol is a synthetic compound that is soluble in organic solvents. It is used for the synthesis of carbocyclic nucleosides, which are analogs of pyrimidine nucleosides. (-)-Corey lactone diol has been shown to inhibit cholesterol synthesis and the synthesis of alkene. (-)-Corey lactone diol also shows anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Fórmula: C₈H₁₂O₄

Pureza: Min. 95%

Peso molecular: 172.18 g/mol

Ref: 3D-FC29747