CAS 3286-46-2

Sulbutiamina

Descrição:

Sulbutiamina é um derivado sintético da tiamina (vitamina B1) projetado para aumentar sua biodisponibilidade e eficácia. É caracterizado por sua natureza lipofílica, que lhe permite atravessar a barreira hematoencefálica de forma mais eficaz do que a própria tiamina. Este composto é frequentemente utilizado por suas potenciais propriedades de melhoria cognitiva, pois pode melhorar a memória e reduzir a fadiga. Sulbutiamina está tipicamente disponível em forma de pó e é solúvel em solventes orgânicos, mas tem solubilidade limitada em água. Sua estrutura química consiste em duas moléculas de tiamina ligadas por um átomo de enxofre, o que contribui para seu perfil farmacológico único. Em termos de segurança, Sulbutiamina é geralmente considerado bem tolerado, embora algumas pessoas possam experimentar efeitos colaterais leves, como dores de cabeça ou desconforto gastrointestinal. Assim como com qualquer suplemento, é aconselhável consultar um profissional de saúde antes de usar, especialmente para indivíduos com condições de saúde subjacentes ou aqueles que estão tomando outros medicamentos. No geral, Sulbutiamina representa um composto interessante no campo dos nootrópicos e suplementos dietéticos.

Fórmula: C₃₂H₄₆N₈O₆S₂

InChI: InChI=1/C32H46N8O6S2/c1-19(2)31(43)45-11-9-27(21(5)39(17-41)15-25-13-35-23(7)37-29(25)33)47-48-28(10-12-46-32(44)20(3)4)22(6)40(18-42)16-26-14-36-24(8)38-30(26)34/h13-14,17-20H,9-12,15-16H2,1-8H3,(H2,33,35,37)(H2,34,36,38)/b27-21+,28-22+

Chave InChI: InChIKey=CKHJPWQVLKHBIH-UHFFFAOYSA-N

SMILES: C(=C(N(CC=1C(N)=NC(C)=NC1)C=O)C)(SSC(=C(N(CC=2C(N)=NC(C)=NC2)C=O)C)CCOC(C(C)C)=O)CCOC(C(C)C)=O

Sinónimos:

• Arcalion
• Arcalion Forte
• Bis(1-(2-isobutyryloxyethyl)-2-(N-((4-amino-2-methyl-5-pyrimidinyl)methyl)formamido)-1-propenyl)disulfid
• Bis(1-(4-amino-2-methyl-5-pyrimidinyl)-2-formyl-3,9-dimethyl-8-oxo-2-aza-7-oxa-3-decen-4-yl)disulfid
• Bisibuthiamine
• Bisibutiamin
• Bisibutiamine
• Brn 0741531
• Formamide, N,N'-(dithiobis(2-(2-hydroxyethyl)-1-methylvinylene))bis(N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-, diisobutyrate (ester)
• Isobutyric acid, diester with N,N′-[dithiobis[2-(2-hydroxyethyl)-1-methylvinylene]]bis[N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]formamide]
• N,N'-(Dithiobis(2-(2-hydroxyethyl)-1-methylvinylene))bis(N-((4-amino-2-methyl-5-pyrimidinyl)methyl)formamide) diisobutyrate (ester)
• O,O'-Diisobutyrylthiamine disulfide
• O-Isobutyroylthiamine disulfide
• O-Isobutyrylthiamine disulfide
• Propanoic acid, 2-methyl-, 1,1′-[dithiobis[3-[1-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]ethylidene]-3,1-propanediyl]] ester
• Propanoic acid, 2-methyl-, dithiobis(3-(1-(((4-amino-2-methyl-5-pyrimidinyl)methyl)formylamino)ethylidene)-3,1-propanediyl) ester
• Sulbutiamina
• Sulbutiamina [INN-Spanish]
• Sulbutiaminum
• Sulbutiaminum [INN-Latin]
• Thiamine disulfide O,O-diisobutyrate
• Unii-42Ncm1Bw43
• Vitaberin
• disulfanediylbis(2E)-2-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}pent-2-ene-3,5-diyl bis(2-methylpropanoate)
• 5-25-12-00169 (Beilstein Handbook Reference)
• [4-[(4-Amino-2-methylpyrimidin-5-yl)methylformylamino]-3-[2-[(4-amino-2-methylpyrimidin-5-yl)methylformylamino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanylpent-3-enyl] 2-methylpropanoate
• 3,3'-Dithiobis[4-[N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-formylamino]-3-penten-1-ol] bis(2-methylpropionate)
• o-isobutyroylthiaminedisulfide
• [4-[(4-amino-2-methylpyrimidin-5-yl)methylformylamino]-3-[2-[(4-amino-2-methylpyrimidin-5-yl)methylformylamino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanylpent-3-enyl] 2-methylpropanoate
• o,o’-diisobutyrylthiaminedisulfide
• SULBUTIAMINE(ARCALION,BISIBUTIAMINE)
• Bis(2-methylpropionic acid)[dithiobis[3-[1-[[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino]ethylidene]-3,1-propanediyl]] ester
• SULBUTIAMINE

Sulbutiamine

CAS: 3286-46-2

Fórmula: C₃₂H₄₆N₈O₆S₂

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 702.89

Ref: 3B-S0964

Propanoic acid, 2-methyl-,dithiobis[3-[1-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]ethylidene]-3,1-propanediyl] ester

CAS: 3286-46-2

Fórmula: C₃₂H₄₆N₈O₆S₂

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 702.8876

Ref: IN-DA00I6AD

Sulbutiamine

CAS: 3286-46-2

Sulbutiamine

Pureza: 97%

Peso molecular: 702.89g/mol

Ref: 54-OR1030080

Sulbutiamine

CAS: 3286-46-2

Fórmula: C₃₂H₄₆N₈O₆S₂

Cor e Forma: White To Off-White Solid

Peso molecular: 702.89

Ref: 4Z-S-211

Sulbutiamine

CAS: 3286-46-2

Sulbutiamine

Pureza: ≥98%

Peso molecular: 702.89g/mol

Ref: 54-BUP16623

Sulbutiamine-d14

CAS: 3286-46-2

Fórmula: C₃₂H₃₂N₈O₆S₂D₁₄

Cor e Forma: White To Off-White Solid

Peso molecular: 716.99

Ref: 4Z-S-212

Sulbutiamine

CAS: 3286-46-2

Sulbutiamine (Bisibuthiamine) is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.

Fórmula: C₃₂H₄₆N₈O₆S₂

Pureza: 99.18% - 99.47%

Cor e Forma: White - Almost White Crystal - Powder

Peso molecular: 702.89

Ref: TM-T5913

Sulbutiamine

Produto Controlado

CAS: 3286-46-2

Applications Sulbutiamine (isobutyryl thiamine disulfide) is a lipophilic derivative of thiamine used for the treatment of asthenia and other related pathological conditions. Sulbutiamine is available over-the-counter in several countries as a component of nutritional supplements.
References Micheau, J., et al.: Pharmacol. Biochem. Behav., 23, 195 (1985), Bettendorff, L., et al.: Biochem. Pharmacol., 40, 2557 (1990), van Reeth, O., et al.: Drugs Today, 35, 187 (1999),

Fórmula: C₃₂H₄₆N₈O₆S₂

Cor e Forma: Off White

Peso molecular: 702.89

Ref: TR-S689250

Sulbutiamine

CAS: 3286-46-2

Sulbutiamine is a thiamine analogue that is used to treat diseases such as Alzheimer's disease and Parkinson's disease. Sulbutiamine also has antimicrobial properties and can be used to treat infectious diseases such as infectious diarrhea. Sulbutiamine has been shown to reduce symptoms of inflammatory bowel disease (IBD) by relieving intestinal inflammation, although it does not affect the course of the disease. Sulbutiamine has also been shown to have effects on the immune system, which may be due to its ability to increase cellular redox potentials in neuro2a cells and human serum. These effects are caused by an indirect antioxidant effect, which results from sulbutiamine's ability to inhibit lipid peroxidation and stimulate glutathione reductase activity.

Fórmula: C₃₂H₄₆N₈O₆S₂

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 702.89 g/mol

Ref: 3D-FS27928

Sulbutiamine

CAS: 3286-46-2

Pureza: 98%

Peso molecular: 702.89

Ref: 10-F979804