CAS 330784-47-9
:Avanafil
Descrição:
Avanafil é um inibidor seletivo da fosfodiesterase tipo 5 (PDE5) usado principalmente para o tratamento da disfunção erétil. É caracterizado pelo seu início de ação rápido, tipicamente dentro de 15 a 30 minutos após a administração, tornando-se uma escolha popular entre os pacientes que buscam alívio rápido. A estrutura química de Avanafil inclui um núcleo de pirazolo[3,4-d]pirimidina, que contribui para sua atividade farmacológica. Tem uma alta afinidade pela enzima PDE5, levando a níveis aumentados de monofosfato de guanosina cíclico (cGMP) no corpo cavernoso, facilitando a ereção peniana em resposta à estimulação sexual. Avanafil é geralmente bem tolerado, com um perfil de efeitos colaterais que pode incluir dores de cabeça, rubor, congestão nasal e dor nas costas. É importante notar que Avanafil não deve ser usado em conjunto com nitratos devido ao risco de hipotensão significativa. Assim como qualquer medicamento, é essencial que os pacientes consultem profissionais de saúde para o uso adequado e possíveis interações.
Fórmula:C23H26ClN7O3
InChI:InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1
Chave InChI:InChIKey=WEAJZXNPAWBCOA-INIZCTEOSA-N
SMILES:C(O)[C@H]1N(C=2N=C(NCC3=CC(Cl)=C(OC)C=C3)C(C(NCC=4N=CC=CN4)=O)=CN2)CCC1
Sinónimos:- (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine
- (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[N-(2-pyrimidinylmethyl)carbamoyl]pyrimidine
- (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
- 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
- 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
- 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
- 5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-
- Spedra
- Ta 1790
- Avanafil
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20 produtos.
(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine
CAS:Fórmula:C23H26ClN7O3Pureza:98%Cor e Forma:SolidPeso molecular:483.9506Ref: IN-DA0034HA
1g35,00€5g73,00€10g111,00€15g157,00€25g177,00€50g325,00€100g701,00€250gA consultar100mg24,00€250mg25,00€4-[(3-Chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
CAS:4-[(3-Chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamidePureza:98%Peso molecular:483.95064g/molAvanafil 100 µg/mL in Acetonitrile:Dimethylsulfoxide
CAS:Fórmula:C23H26ClN7O3Cor e Forma:Single SolutionPeso molecular:483.95Avanafil
CAS:Fórmula:C23H26ClN7O3Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:483.96Avanafil
CAS:Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.Fórmula:C23H26ClN7O3Pureza:99.03% - >99.99%Cor e Forma:White SolidPeso molecular:483.95Avanafil
CAS:Fórmula:C23H26ClN7O3Pureza:≥ 98.0% (dried basis)Cor e Forma:White to off-white crystalline powderPeso molecular:483.95Avanafil
CAS:Produto Controlado<p>Applications A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.<br>References Hatzimouratidis, K., et al.: Drugs, 68, 231 (2008);<br></p>Fórmula:C23H26ClN7O3Cor e Forma:WhitePeso molecular:483.95Avanafil - Bio-X ™
CAS:Avanafil is a phosphodiesterase-5 (PDE5) inhibitor drug that can be used as a treatment for male erectile dysfunction. It works by inhibiting the production of PDE5, which is an enzyme that regulates the levels of cGMP in the penis. Elevated levels of cGMP, results in an increase of blood flow to the penis.Fórmula:C23H26ClN7O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:483.95 g/molAvanafil
CAS:<p>Avanafil is a drug that can be used as a treatment for male erectile dysfunction. It works by inhibiting the production of PDE5, which is an enzyme that regulates the levels of cGMP in the penis. Avanafil has been shown to be effective when taken at a dose of 100 mg; this is because it takes about 30 minutes for avanafil to reach its peak level. Avanafil has a chemical stability that is greater than 12 hours, with an average lifespan of 24 hours. The drug also has no major drug interactions and does not inhibit any other drugs from working.</p>Fórmula:C23H26ClN7O3Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:483.95 g/molAvanafil-d5
CAS:Produto Controlado<p>Applications Unlabeled compound, Avanafil (A794670), is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.<br>References Hatzimouratidis, K., et al.: Drugs, 68, 231 (2008);<br></p>Fórmula:C23H21D5ClN7O3Cor e Forma:NeatPeso molecular:488.98
![4-[(3-Chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmet…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR302290.jpg&w=3840&q=75)
