CAS 330936-69-1

L-Alanina, L-metionil-L-alanil-L-prolil-L-arginilglicil-L-fenilalanil-L-seril-L-cisteinil-L-leucil-L-leucil-L-leucil-L-leucil-L-treonil-L-seril-L-a-glutamil-L-isoleucil-L-a-aspartil-L-leucil-L-prolil-L-valil-L-lisil-L-arginil-L-arginil-

Descrição:

A substância química à qual você se refere, com o nome "L-Alanina, L-metionil-L-alanil-L-prolil-L-arginilglicina-L-fenilalanina-L-serina-L-cisteína-L-leucina-L-leucina-L-leucina-L-leucina-L-treonina-L-serina-L-a-glutamato-L-isoleucina-L-a-aspartato-L-leucina-L-prolina-L-valina-L-lisina-L-arginina-L-arginina-" e número CAS 330936-69-1, é um peptídeo complexo composto por múltiplos aminoácidos. Esta substância é caracterizada por sua sequência de L-aminoácidos, que são os blocos de construção das proteínas. A presença de vários aminoácidos sugere uma potencial atividade biológica, possivelmente relacionada à síntese de proteínas ou vias de sinalização. A disposição específica desses aminoácidos pode influenciar a conformação do peptídeo, sua estabilidade e interações com outras biomoléculas. Além disso, a presença de aminoácidos que contêm enxofre, como metionina e cisteína, pode contribuir para a formação de ligações dissulfeto, melhorando a integridade estrutural. No geral, as características deste peptídeo seriam determinadas por sua sequência, peso molecular, solubilidade e funções biológicas potenciais, tornando-o de interesse na pesquisa bioquímica e farmacêutica.

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Sinónimos:

• 1-24-Proteinhumanin (human)
• 188: PN: US20090053203 SEQID: 188 claimed protein
• 1: PN: JP2006213632SEQID: 1 claimed protein
• 1:PN: WO2009040017 PAGE: 98 claimed protein
• 2: PN: WO03045988 SEQID: 2 claimedsequence
• 317: PN:WO2005051988 SEQID: 317 claimed protein
• 369: PN: WO0176532 SEQID: 91 claimedprotein
• 48: PN: WO0181361 SEQID: 47 claimed protein
• 4: PN: WO2008115525 SEQID: 188claimed protein
• 60: PN:WO2008058016 SEQID: 60 claimed protein
• 7: PN: WO0121786 SEQID: 5 claimedsequence
• Humanin
• Humanin(human clone CG202524-01)
• Protein (human clone 1 humanin sequence homolog)
• Protein Humanin (human)
• T lymphocyte activation-associated protein PRO86272(human)
• Humanin Trifluoroacetate
• 1: PN: US20060100253 SEQID: 1 unclaimed sequence
• Humanin (human)
• 3: PN: WO03106683 SEQID: 3 claimed sequence
• 5: PN: WO0121787 SEQID: 5 claimed sequence
• 40: PN: WO2004047728SEQID: 7249 claimed sequence
• 4:PN: WO2006019365 SEQID: 4 claimed sequence
• 2: PN: WO2009117596 SEQID: 1 unclaimed sequence
• 7: PN: WO2009135165 SEQID: 14 unclaimed sequence
• H-MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-SER-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA-OH
• Leucostoma persoonii (Nitschke) H&ouml
• MAPRGFSCLLLLTSEIDLPVKRRA
• L-Alanine, L-methionyl-L-alanyl-L-prolyl-L-arginylglycyl-L-phenylalanyl-L-seryl-L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-L-seryl-L- alpha-glutamyl-L-isoleucyl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-valyl-L-lysyl-L-arginyl-L-arginyl-
• MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-SER-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA TRIFLUOROACETATE
• 1-24-Protein humanin (human)
• H-MAPRGFSCLLLLTSEIDLPVKRRA-OH
• Humanin, HN
• MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-SER-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA
• Humanin (1)
• Drepanopeziza populorum (Desm.) H&ouml
• HNMET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-SER-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA
• MAPGSGCLLLLTSEIDLPVKRRA
• HN
• Humanin(human)trifluoroacetate
• Humanin S14-G
• Humanin(human) acetate

Humanin, human

CAS: 330936-69-1

For cellular and molecular biology applications

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Peso molecular: 2687.22

Ref: 02-J66525

Humanin (human)

CAS: 330936-69-1

Humanin (HN) is a polypeptide suppressing neuronal cell death induced by several familial Alzheimer’s disease genes and by amyloid β-protein (1-43) (human). It has been shown that amyloid β-protein (1-40) and amyloid β-protein (1-42) secretion is not affected by humanin in F11 cells expressing the familial Alzheimer’s disease gene K595N/M596L-APP. Inhibitory actions on neuronal cell death triggered by K595N/M596L-APP directly and caused by amyloid β-protein have been suggested.

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Pureza: 96.0%

Cor e Forma: White Whitish Powder

Peso molecular: 2687.27

Ref: 01-4038276

Humanin (human)

CAS: 330936-69-1

Encoded for by mitochondrial DNA, Humanin is an endogenous peptide known to be a ‘rescue factor’ with the ability to abolish neuronal cell death. This characteristic has promoted Humanin as a potential treatment for Alzheimer’s disease. Another function of Humanin is it can inhibit mitochondira-dependent apoptosis through preventing the formation of apoptotic bodies and the release of Cytochrome C.Humanin has been found to be related to aging related cardiovascular disease (ACVDs) due to evidence of Humanin serum levels as age increases. Furthermore Humanin increases the expression of antioxidant defense system proteins and impedes complexes I and III from their activity in the electron transport chain in myocardial cells and mitochondria, therefore decreasing oxidative stress damage caused by H2O2. Humanin further reduces reactive oxygen species production and protects cardiomyocytes and fibroblasts, from oxidative stress.Overall Humanin has a variety of protective functions such as mitochondrial homeostasis and redox systems regulation, anti-aging, prevention of myocardial fibrosis, anti-inflammation, metabolism improvement and autophagy promotion. It has also been found to improve beta-cell survival and thus can be used as a diabetes treatment due to it improving insulin secretion and resistance.

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 2,687.28 g/mol

Ref: 3D-PH17011

Humanin

CAS: 330936-69-1

Encoded for by mitochondrial DNA, Humanin is an endogenous peptide known to be a ‘rescue factor’ with the ability to abolish neuronal cell death. This characteristic has promoted Humanin as a potential treatment for Alzheimer’s disease. Another function of Humanin is it can inhibit mitochondira-dependent apoptosis through preventing the formation of apoptotic bodies and the release of Cytochrome C.
Humanin has been found to be related to aging related cardiovascular disease (ACVDs) due to evidence of Humanin serum levels as age increases. Furthermore Humanin increases the expression of antioxidant defense system proteins and impedes complexes I and III from their activity in the electron transport chain in myocardial cells and mitochondria, therefore decreasing oxidative stress damage caused by H2O2. Humanin further reduces reactive oxygen species production and protects cardiomyocytes and fibroblasts, from oxidative stress.
Overall Humanin has a variety of protective functions such as mitochondrial homeostasis and redox systems regulation, anti-aging, prevention of myocardial fibrosis, anti-inflammation, metabolism improvement and autophagy promotion. It has also been found to improve beta-cell survival and thus can be used as a diabetes treatment due to it improving insulin secretion and resistance. This product is available as a 0.5mg vial.

Fórmula: C₁₁₉H₂₀₄N₃₄O₃₂S₂

Pureza: Min. 95%

Peso molecular: 2,687.2 g/mol

Ref: 3D-PHN-4384-V