CAS 3338-32-7

Éster 4-terc-butil-1-(N-succinimidil) do ácido Z-L-aspártico

Descrição:

Éster 4-terc-butil-1-(N-succinimidil) do ácido Z-L-aspártico, com o número CAS 3338-32-7, é um composto químico que serve como um derivado do ácido aspártico, um aminoácido importante na bioquímica. Este composto apresenta um grupo Z-protetor, que melhora sua estabilidade e solubilidade, tornando-o adequado para várias aplicações sintéticas, particularmente na síntese de peptídeos. A presença do grupo éster succinimidila indica que pode ser usado para reações de acilo, facilitando a formação de ligações amida com nucleófilos, como aminas. O grupo tert-butilo contribui para a hindrance estérica, o que pode influenciar a reatividade e seletividade do composto em reações químicas. Éster 4-terc-butil-1-(N-succinimidil) do ácido Z-L-aspártico é frequentemente utilizado no desenvolvimento de produtos farmacêuticos e bioconjugados, devido à sua capacidade de modificar seletivamente biomoléculas. Sua estabilidade em condições fisiológicas e compatibilidade com vários grupos funcionais o tornam uma ferramenta valiosa na síntese orgânica e na química medicinal.

Fórmula: C₂₀H₂₄N₂O₈

InChI: InChI=1/C20H24N2O8/c1-20(2,3)29-17(25)11-14(18(26)30-22-15(23)9-10-16(22)24)21-19(27)28-12-13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3,(H,21,27)

Chave InChI: InChIKey=JUMSBOKRGDETHL-AWEZNQCLSA-N

SMILES: O(C([C@@H](NC(OCC1=CC=CC=C1)=O)CC(OC(C)(C)C)=O)=O)N2C(=O)CCC2=O

Sinónimos:

• <span class="text-smallcaps">L</span>-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester
• Aspartic acid, N-carboxy-, N-benzyl 4-tert-butyl ester, succinimido deriv., <span class="text-smallcaps">L</span>-
• Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3S)-
• Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (S)-
• N-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid 5-tert-butyl-1-hydroxysuccinimide diester
• Succinimide, N-[(N-carboxy-<span class="text-smallcaps">L</span>-α-aspartyl)oxy]-, N-benzyl tert-butyl ester
• Z-Asp(Otbu)-Osu
• Succinimide, N-[(N-carboxy-L-α-aspartyl)oxy]-, N-benzyl tert-butyl ester
• Aspartic acid, N-carboxy-, N-benzyl 4-tert-butyl ester, succinimido deriv., L-
• L-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester
• (S)-4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(benzyloxy)carbonyl]amino]butyric acid tert-butyl ester
• Z-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester
• CBZ-Asp(OBut)-OSu
• O4-tert-butyl O1-(2,5-dioxopyrrolidin-1-yl) 2-(phenylmethoxycarbonylamino)butanedioate
• N-BENZYLOXYCARBONYL-L-ASPARTIC ACID 4-TERT-BUTYL-1-(N-SUCCINIMIDYL) ESTER
• N-Benzyloxycarbonyl-L-aspartic acid-4-tert-butyl-1- (N-hydroxysuccinimide)-
• 1-tert-butyl 2,5-dioxopyrrolidin-1-yl (3S)-3-{[(benzyloxy)carbonyl]amino}butanedioate
• tert-butyl (S)-4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]butyrate
• N-CBZ-beta-tert-butyl-L-aspartic acid N-hydroxysuccinimide
• 2-(benzyloxycarbonylamino)succinic acid O4-tert-butyl ester O1-succinimido ester
• Z-ASPARTIC ACID T-BUTYLESTER HYDROXYSUCCINIMIDESTER
• Z-L-Asp(OtBu)-OSu
• Z-L-Aspartic acid β-tert·butyl ester α- N-hydro
• CBZ-Asp(OtBu)-Osu
• Z-ASPARTIC ACID(OTBU)-OSU
• Z-L-ASPARTIC ACID 4-TERT-BUTYL-1-(N-SUCCINIMIDYL) ESTER
• Z-L-aspartic acid beta-tert-butyl ester beta-N-hydroxysucciniMide ester
• N-Cbz-β-t-butyl-L-aspartic acid N-hydroxysuccinimide ester, Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester
• Z-L-aspartic acid β-tert·butyl ester α-N-hydroxysuccinimide ester
• Z-ASP(OTBU)-OSU USP/EP/BP
• N-Benzyloxycarbonyl-L-aspartic acid 4-tert-butyl ester 1-(N-succinimidyl) ester
• 4-O-tert-butyl 1-O-(2,5-dioxopyrrolidin-1-yl) (2S)-2-(phenylmethoxycarbonylamino)butanedioate
• Z-ASPARTIC ACID TERT-BUTYL ESTER HYDROXYSUCCINIMIDE ESTER
• N-Cbz-β-t-butyl-L-aspartic acid N-hydroxysuccinimide ester
• N-CBZ-BETA-TERT-BUTYL-L-ASPARTIC ACID N-HYDROXYSUCCINIMIDE ESTER
• Z-ASP(OBUT)-OSU
• n-benzyloxycarbonyl-l-aspartic acid 4-tert-butyl 1-(n-succinimidyl)
• (S)-4-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl)-2-(((benzyloxy)carbonyl)amino)succinate
• N-CBZ-B-T-BUTYL-L-ASPARTIC ACIDN-HYDROXY SUCCINIMID
• CBZ-L-ASPARTIC ACID .BETA.-TERT-BUTYL ESTER .ALPHA.-N-HYDROXYSUCCINIMIDE ESTER
• Z-L-ASPARTIC ACID BETA-T-BUTYL ESTER ALPHA-N-HYDROXYSUCCINIMIDE ESTER
• Z-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester≥ 98% (HPLC)
• N-alpha-Benzyloxycarbonyl-L-aspartic acid alpha-(N-hydroxysuccinimidyl) beta-t-butyl ester
• N-(Benzyloxycarbonyl)-L-aspartic acid 1-succinimidyl 4-tert-butyl ester
• Z-L-ASPARTIC ACID 4-TERT-BUTYL-1-(N- &
• BENZYLOXYCARBONYL-L-ASPARTIC ACID BETA-T-BUTYL ESTER N-HYDROXYSUCCINIMIDE ESTER
• Z-L-Asp(tBu)-OSu
• BENZYLOXYCARBONYL-L-ASPARTIC ACID BETA-T-BUTYL-ALPHA-N-HYDROXYSUCCINIMIDE DI-ESTER
• N-cbz-B-T-butyl-L-aspartic acid*N-hydroxysuccinim

z-asp(otbu)-osu

CAS: 3338-32-7

Fórmula: C₂₀H₂₄N₂O₈

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 420.4132

Ref: IN-DA00BYAG

(S)-4-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) 2-(((benzyloxy)carbonyl)amino)succinate

CAS: 3338-32-7

(S)-4-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) 2-(((benzyloxy)carbonyl)amino)succinate

Pureza: 95%

Peso molecular: 420.42g/mol

Ref: 54-OR1070598

z-asp(otbu)-osu

CAS: 3338-32-7

Fórmula: C₂₀H₂₄N₂O₈

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 420.418

Ref: 10-F045485