CAS 337376-15-5

Icodextrina

Descrição:

Icodextrina é um carboidrato sintético derivado da hidrólise enzimática do amido, utilizado principalmente em aplicações médicas, particularmente em soluções para diálise peritoneal. É um polímero de glicose composto por vários comprimentos de cadeia, o que contribui para suas propriedades únicas. Icodextrina é caracterizado por sua capacidade de criar um gradiente osmótico, facilitando a remoção de excesso de fluido do corpo enquanto minimiza o risco de complicações relacionadas à glicose. Geralmente é apresentado como uma solução clara e incolor e é conhecido por sua biocompatibilidade e baixa imunogenicidade. A substância é estável em condições normais e possui um peso molecular relativamente baixo, o que permite uma absorção e excreção eficientes. Além disso, Icodextrina tem um baixo valor calórico, tornando-o adequado para pacientes que necessitam de manejo de fluidos sem ingestão calórica significativa. Seu uso em ambientes clínicos tem sido associado a melhores resultados para os pacientes em diálise, particularmente em termos de ultrafiltração e equilíbrio de fluidos. No geral, Icodextrina representa um avanço significativo no manejo de pacientes submetidos à diálise peritoneal.

Fórmula: Unspecified

InChI: InChI=1/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12-,20-15-,24-14-/t23-,25-,26+,27+,30-,37-,38+,41-,45+/m1/s1

Sinónimos:

• (11beta,16beta)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
• A complex polyglucopyranose produced by the enzymatic hydrolysis of corn. It is primarily composed of alpha-1,4-glocopyranose linkage with less that 10 percent alpha-1,6 linkage
• platinum
• Adept (polysaccharide)
• 1-cyano-2-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
• (3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
• A complex alpha-D-glycopyranan produced by the enzymatic hydrolysis of corn. It is primarily composed of (1-4)-alpha-D-glucopyrano linkage with less than 10 percent (1-6)-alpha linkage. Dextrin, having more than 85% of its molecules with molecular masses between 1640 and 45,000 with a claimed-average molecular mass of approximately 20,000
• 2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol
• 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]{4-[2-(piperidin-1-yl)ethoxy]phenyl}methanone
• 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
• (11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
• N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
• azanide
• 2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
• A complex polyglucopyranose produced by the enzymatic hydrolysis of corn. It is primarily composed of alpha-1,4-glocopyranose linkage with less that 10 percent alpha-1,6 linkage
• 1-{amino[(4-chlorophenyl)amino]methylidene}-2-propan-2-ylguanidine
• (11beta,16beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine
• 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide
• 2-phenyl-1H-indene-1,3(2H)-dione
• 1-[4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone
• Icodextrin
• 2-benzyl-4,5-dihydro-1H-imidazole
• 5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
• 1-methyl-1,3-dihydro-2H-imidazole-2-thione
• methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
• (6R,7R)-7-{[amino(phenyl)acetyl]amino}-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
• 5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}quinazoline-2,4-diamine
• Icodial
• 2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate
• N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
• 1-(1,2-benzoxazol-3-yl)methanesulfonamide
• 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
• 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 1-methyl-3-phenylpyrrolidine-2,5-dione
• 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
• Icodextrin, sodium chloride, sodium lactate, calcium chloride
• 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
• N,N-dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine
• 2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one
• N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine
• 2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol
• 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol
• ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
• (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2E)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1,3-dibenzyl-2-oxodecahydrothieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium
• 5-[bis(2-chloroethyl)amino]pyrimidine-2,4(1H,3H)-dione
• 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydroquinolin-2(1H)-one
• N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
• Adept
• 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine
• N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine
• Adept (polysaccharide)
• 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
• 2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile
• ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
• 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraran-2'-ium
• (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (non-preferred name)
• 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
• N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide
• cyclobutane-1,1-dicarboxylic acid
• (5Z,7E,22E)-9,10-secoergosta-5,7,22-trien-3-ol
• 5,5-diphenylimidazolidine-2,4-dione
• 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
• 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate
• N,N,2-trimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine
• Adept
• N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine
• 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
• (11beta,17beta)-11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(prop-1-yn-1-yl)estra-4,9-dien-3-one
• (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
• 2-[(carbamoyloxy)methyl]-2-methylpentyl propan-2-ylcarbamate (non-preferred name)
• 2-chloro-N-(2-chloroethyl)-N-methylethanamine
• 3-ethyl-4-methyl-N-[2-(4-{[(4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
• (17beta)-estra-1,3,5(10)-triene-3,17-diol
• 5-fluoropyrimidine-2,4(1H,3H)-dione
• methyl propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• 17,21-dihydroxypregna-1,4-diene-3,11,20-trione
• 3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
• 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
• 2-[({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino)oxy]ethanamine
• 2-{(Z)-[5-(hydroxymethyl)-3H-indol-3-ylidene]methyl}-N'-pentylhydrazinecarboximidamide
• [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](2,3-dihydro-1,4-benzodioxin-2-yl)methanone
• 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
• 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol
• 4-(dipropylsulfamoyl)benzoic acid
• 1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline
• Extraneal
• (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranoside
• (8R)-3-(2-deoxypentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
• (4Z)-4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
• 9-(beta-D-arabinofuranosyl)-9H-purin-6-amine hydrate (1:1)
• (1R,5R)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azoniabicyclo[3.2.1]octane
• platinum(2+) ethanedioate - cyclohexane-1,2-diamine (1:1:1)
• 6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
• 4-amino-N-[2-(diethylamino)ethyl]benzamide
• N,3-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
• 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
• (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
• 2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
• 4-{[(E)-(4-chlorophenyl)(3-fluoro-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino}butanamide
• 3-ethyl-3-methylpyrrolidine-2,5-dione
• 4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
• (3S)-9,10-secocholesta-5,7,10-trien-3-ol
• 9-methyl-3-(2H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
• 2-[(1E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-en-1-yl]pyridine
• 4-chloro-N-(propylcarbamoyl)benzenesulfonamide
• (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
• (5alpha)-3,14-dihydroxy-17-methyl-4,5-epoxymorphinan-6-one
• N-[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline
• ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate
• N~2~-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
• 5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione
• 6-phenylpteridine-2,4,7-triamine
• 3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol
• 1-{[(1Z)-(5-nitrofuran-2-yl)methylidene]amino}imidazolidine-2,4-dione
• ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 4-aminohex-5-enoic acid
• 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
• (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-8-oxo-3-[(1E)-prop-1-en-1-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
• 2-[(5-nitrofuran-2-yl)methylidene]hydrazinecarboxamide
• 2-O-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-O-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-O-sulfohexopyranuronosyl-(1->4)-2-(acetylamino)-2-deoxy-6-O-sulfohexopyranose
• 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol
• methyl (5S,7S,9S)-9-[(2beta,3beta,4beta,5alpha,12beta,19alpha)-3-carbamoyl-3,4-dihydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidin-15-yl]-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole-9-carboxylate
• [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
• (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine
• 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• 2,2'-hexane-1,6-diylbis(1-{amino[(4-chlorophenyl)amino]methylidene}guanidine)
• [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate (non-preferred name)
• (3E)-6-oxo-3-{[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazono}cyclohexa-1,4-diene-1-carboxylic acid
• 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
• propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
• N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
• 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)
• 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium
• 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
• [(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
• (9S,12Z,14R,15R,16S,17S,18S,19S,20R,21R,22Z,24Z)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadeca[1,11,13]trienoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl acetate
• 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol
• 8-chloro-11-(4-methylpiperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine
• (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
• (3Z)-3-[hydroxy(pyridin-2-ylamino)methylidene]-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide
• 2'-deoxy-5-iodouridine
• (5alpha)-3,14-dihydroxy-17-prop-2-en-1-yl-4,5-epoxymorphinan-6-one
• 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one
• 4-[(3-methylphenyl)amino]-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide
• (1S)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}dodecyl N-formyl-L-leucinate
• 2-amino-9-[(2-hydroxyethoxy)methyl]-3,9-dihydro-6H-purin-6-one
• 4-amino-5-chloro-N-{1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl}-2-methoxybenzamide
• N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
• N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide
• 5-chloro-1,3-benzoxazol-2(3H)-one
• 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
• (11E)-13-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2R,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-12-methyl-10-oxotridec-11-enoic acid (non-preferred name)

Icodextrin

CAS: 337376-15-5

Pureza: 95%

Cor e Forma: Solid

Peso molecular: G/Mol

Ref: IN-DA0037O4