CAS 3413-58-9

Cloridrato de cinchonan-9-ol, 6'-etoxi-10,11-diidro-, (1:1), (8α,9R)-

Descrição:

Cloridrato de cinchonan-9-ol, 6'-etoxi-10,11-diidro-, (1:1), (8α,9R)- é um composto químico derivado dos alcaloides da quina, conhecidos por suas propriedades medicinais, particularmente no tratamento da malária. Este composto apresenta uma estrutura bicíclica complexa típica dos derivados da quina, caracterizada por uma estrutura de quinolina. A presença do grupo etóxi na posição 6′ aumenta sua solubilidade e bioatividade. Como sal de cloridrato, é tipicamente mais estável e solúvel em soluções aquosas, tornando-o adequado para aplicações farmacêuticas. A estereoisomeria específica indicada por (8α,9R) sugere uma disposição tridimensional particular de átomos, que pode influenciar significativamente a atividade biológica do composto e sua interação com alvos biológicos. No geral, este composto exemplifica a diversidade estrutural e as potenciais aplicações terapêuticas dos alcaloides derivados da quina na química medicinal.

Fórmula: C₂₁H₂₈N₂O₂·ClH

InChI: InChI=1S/C21H28N2O2.ClH/c1-3-14-13-23-10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-4-2)12-18(17)19;/h5-7,9,12,14-15,20-21,24H,3-4,8,10-11,13H2,1-2H3;1H/t14-,15-,20-,21+;/m0./s1

Chave InChI: InChIKey=QNRATNLHPGXHMA-XZHTYLCXSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OCC)=C2)N=CC1)[C@]3([N@@]4C[C@H](CC)[C@](C3)(CC4)[H])[H].Cl

Sinónimos:

• (3alpha,9R)-6'-ethoxy-10,11-dihydrocinchonan-1-ium-9-ol
• (9R)-6'-ethoxy-10,11-dihydrocinchonan-1-ium-9-ol
• 6'-Ethoxy-10,11-Dihydrocinchonan-9-Ol
• Cinchonan-9-ol, 6'-ethoxy-10,11-dihydro-, monohydrochloride, (8alpha,9R)- (9CI)
• Cinchonan-9-ol, 6′-ethoxy-10,11-dihydro-, hydrochloride (1:1), (8α,9R)-
• Cinchonan-9-ol, 6′-ethoxy-10,11-dihydro-, monohydrochloride, (8α,9R)-
• Ethylhydrocupreine HCl
• Hydrocupreine, O-6'-ethyl-, monohydrochloride (VAN)
• Hydrocupreine, O-ethyl-, hydrochloride
• Hydrocupreine, O^6′-ethyl-, monohydrochloride
• Hydrocupreine, ethyl ester, hydrochloride
• Neumolisina
• Nsc 5361
• Numoquin hydrochloride
• O-Ethylhydrocupreine hydrochloride
• Optochin hydrochloride
• Optoquin hydrochloride
• Optoquinhydrochloride
• Rhombic

Ethylhydrocupreine hydrochloride, 97%

CAS: 3413-58-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₃H₃₃ClN₂O₂

Pureza: 97%

Cor e Forma: White to cream, Crystals or powder or crystalline powder

Peso molecular: 404.98

Ref: 02-B21627

Ethylhydrocupreine (hydrochloride)

CAS: 3413-58-9

Fórmula: C₂₁H₂₉ClN₂O₂

Pureza: 98%

Peso molecular: 376.9202

Ref: IN-DA003QJD

Ethylhydrocupreine hydrochloride

CAS: 3413-58-9

Ethylhydrocupreine hydrochloride

Pureza: ≥98%

Peso molecular: 376.92g/mol

Ref: 54-BUP11789

Ethylhydrocupreine hydrochloride

CAS: 3413-58-9

Fórmula: C₂₁H₂₆N₂O₂HCl

Peso molecular: 374.91

Ref: 7W-GP2956

Ethylhydrocupreine hydrochloride

CAS: 3413-58-9

Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a derivative of quinine with antimicrobial activity against Streptococcus pneumoniae.

Fórmula: C₂₁H₂₉ClN₂O₂

Pureza: 99.73% - 99.86%

Cor e Forma: Solid

Peso molecular: 376.92

Ref: TM-T40417

Ethylhydrocupreine HCl

CAS: 3413-58-9

Ethylhydrocupreine HCl is a cavity treatment that is used to treat cancer. It is a laboratory diagnosis, which means it can be used to diagnose and monitor the progression of cancer. Ethylhydrocupreine HCI has been shown to have hemolytic activity against erythrocytes and has been shown in laboratory experiments to inhibit the growth of pneumococcus and other bacteria by interfering with DNA synthesis. Ethylhydrocupreine HCI is being studied as an anticancer agent that may prevent the spread of cancer cells. The drug binds to dsDNA, inhibiting replication and transcription, leading to cell death. Ethylhydrocupreine HCI also inhibits protein synthesis by binding to RNA polymerase and preventing elongation of RNA chains.

Fórmula: C₂₁H₂₈N₂O₂·HCl

Pureza: Min. 95%

Cor e Forma: White Yellow Powder

Peso molecular: 376.92 g/mol

Ref: 3D-FE30579