CAS 3413-72-7

5-(3-Metiltriazen-1-il)imidazol-4-carboxamida

Descrição:

5-(3-Metiltriazen-1-il)imidazol-4-carboxamida, também conhecido pelo seu número CAS 3413-72-7, é um composto químico que pertence à classe dos derivados de triazena. Esta substância apresenta um grupo funcional de triazena, que é caracterizado pela presença de uma ligação dupla nitrogênio-nitrogênio, contribuindo para sua reatividade e potencial atividade biológica. O anel de imidazol em sua estrutura proporciona estabilidade adicional e é conhecido por seu papel em vários processos bioquímicos. O grupo carboxamida aumenta sua solubilidade em solventes polares e pode influenciar sua interação com alvos biológicos. Este composto tem sido estudado por suas potenciais aplicações em química medicinal, particularmente no desenvolvimento de agentes antitumorais, devido à sua capacidade de induzir danos ao DNA em células cancerosas. Suas características estruturais únicas permitem várias modificações, o que pode levar a derivados com maior eficácia ou menor toxicidade. No geral, 5-(3-Metiltriazen-1-il)imidazol-4-carboxamida representa um composto significativo no campo da pesquisa farmacêutica.

Fórmula: C₅H₈N₆O

InChI: InChI=1/C5H8N6O/c1-7-11-10-5-3(4(6)12)8-2-9-5/h2,7,11H,1H3,(H2,6,12)/b10-5+

Chave InChI: InChIKey=MVBPAIHFZZKRGD-UHFFFAOYSA-N

SMILES: C(N)(=O)C1=C(N=NNC)N=CN1

Sinónimos:

• Imidazole-4(or 5)-carboxamide, 5(or 4)-(3-methyl-1-triazeno)-
• 1H-Imidazole-4-carboxamide, 5-(3-methyl-1-triazenyl)-
• 5-[2-(Methylimino)hydrazinyl]-1H-imidazole-4-carboxamide
• 1H-Imidazole-4-carboxamide, 5-[2-(methylimino)hydrazinyl]-
• Imidazole-4-carboxamide, 5-(3-methyl-1-triazeno)-
• nsc407347
• Monomethyl triaizeno imidazole carboxamide
• Monomethyl Triaizeno Imidazole Carboxamide, 3-Methyl(triazenyl)imidazole-4-carboxamide, 5-(3-Methyltriazen-1-yl)imidazole-4-carboxamide, NSC 407347
• 5(or4)-(3-methyl-1-triazeno)-imidazole-4(or5)-carboxamid
• mtic
• 5-(3-methyl-1-triazenyl)-1h-imidazole-4-carboxamid
• 1H-IMidazole-4-carboxaMide,5-[2-(MethyliMino)hydrazinyl]- (Related Reference)
• 5-(3-Methyl-1-triazenyl)-1H-imidazole-4-carboxamide
• 5-(3-methyl-1-triazeno)-imidazole-4-carboxamid
• 5-(3-Methyltriazene-1-yl)-1H-imidazole-4-carboxamide
• MONOMETHYL-TRIAZENOIMIDAZOLE-CARBOXAMIDE
• MonomethylTriaizenoImidazoleCarboxamide,3-Methyl-(triazen-yl)-imidazole-4-carboxamide,NSC407347,
• 5-(3-methyl-1-triazeno)imidazole-4-carboxamide
• 3-Methyl(triazenyl)iMidazole-4-carboxaMide

MTIC

CAS: 3413-72-7

Fórmula: C₅H₈N₆O

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 168.1566

Ref: IN-DA00C94K

Temozolomide Metabolite-MTIC

CAS: 3413-72-7

Fórmula: C₅H₈N₆O

Cor e Forma: Pink Solid

Peso molecular: 168.16

Ref: 4Z-T-343

MTIC

CAS: 3413-72-7

MTIC

Pureza: 98%

Peso molecular: 168.16g/mol

Ref: 54-OR1035829

MTIC

CAS: 3413-72-7

MTIC has anticancer and antitumor activity and can be used to study melanoma.

Fórmula: C₅H₈N₆O

Pureza: 99.61%

Cor e Forma: Solid

Peso molecular: 168.16

Ref: TM-T35688

MTIC

CAS: 3413-72-7

Applications A metabolite of Temozolomide, an antineoplastic.

Fórmula: C₅H₈N₆O

Cor e Forma: Off-White

Peso molecular: 168.16

Ref: TR-M760000

Monomethyl triazeno imidazole carboxamide

CAS: 3413-72-7

Monomethyl triazeno imidazole carboxamide (MTIC) is a drug that is used to treat cancer. It has been shown to inhibit the proliferation of tumor cells and induce apoptosis by inhibiting the expression of proteins, such as Bcl-2, which are involved in regulating mitochondrial membrane potential. MTIC has also been shown to inhibit protein synthesis and cell signaling pathways, such as the PI3K/Akt pathway. The use of MTIC for diagnosis purposes can be achieved using electrochemical impedance spectroscopy. A concentration–time curve can be obtained by incubating a biological sample with MTIC and measuring cell response using an impedance spectrophotometer. The clinical properties of MTIC include its ability to be administered orally or intravenously, have low toxicity, and inhibit the growth of tumor cells in vivo and in vitro.

Fórmula: C₅H₈N₆O

Pureza: (¹H-Nmr) Min. 95 Area-%

Cor e Forma: White Powder

Peso molecular: 168.16 g/mol

Ref: 3D-FM26098

(E)-5-(3-METHYLTRIAZ-1-EN-1-YL)-1H-IMIDAZOLE-4-CARBOXAMIDE

CAS: 3413-72-7

Fórmula: C₅H₈N₆O

Pureza: 95.0%

Peso molecular: 168.16

Ref: 10-F535762

MTIC

CAS: 3413-72-7

Pureza: 98%

Peso molecular: 168.16

Ref: 10-F986866

Monomethyl Triaizeno Imidazole Carboxamide

CAS: 3413-72-7

Fórmula: C₅H₈N₆O

Peso molecular: 168.16

Ref: ST-EA-CP-T15008