CAS 34183-22-7

Cloridrato de propafenona

Descrição:

Cloridrato de propafenona é um composto farmacêutico utilizado principalmente como agente antiarrítmico para o tratamento de certos tipos de batimentos cardíacos irregulares, especificamente fibrilação atrial e taquicardia ventricular. É classificado como um medicamento antiarrítmico de Classe IC, o que significa que atua bloqueando os canais de sódio nas células cardíacas, estabilizando assim a membrana cardíaca e reduzindo a excitabilidade. A substância aparece como um pó cristalino branco a off-white e é solúvel em água e álcool, o que facilita sua formulação em várias formas de dosagem, como comprimidos e soluções orais. Cloridrato de propafenona é conhecido por sua capacidade de prolongar o período refratário nos tecidos cardíacos, ajudando assim a restaurar o ritmo cardíaco normal. Também pode apresentar propriedades beta-bloqueadoras, contribuindo para seus efeitos terapêuticos. Os efeitos colaterais comuns podem incluir tontura, fadiga e distúrbios gastrointestinais. Devido ao seu perfil farmacológico, é necessário um monitoramento cuidadoso durante o tratamento, especialmente em pacientes com condições cardíacas preexistentes ou aqueles que tomam outros medicamentos que podem interagir com seu metabolismo.

Fórmula: C₂₁H₂₇NO₃·ClH

InChI: InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H

Chave InChI: InChIKey=XWIHRGFIPXWGEF-UHFFFAOYSA-N

SMILES: O(CC(CNCCC)O)C1=C(C(CCC2=CC=CC=C2)=O)C=CC=C1.Cl

Sinónimos:

• 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride
• 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, hydrochloride
• 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (1:1)
• 1-{2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl}-3-Phenylpropan-1-One Hydrochloride (1:1)
• 2'-(2-Hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenone hydrochloride
• Arythmol
• Baxarytmon
• Fenoprain
• Pronon
• Propafenon hydrochlorid
• Propafenon hydrochlorid [German]
• Propafenone hydrochloride
• Propafenone hydrochloride [USAN:JAN]
• Propiophenone, 2'-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-, hydrochloride
• Rhythmonorm
• Rythmol
• Rythmol SR
• Rytmonorm
• Sa 79
• Unii-33Xch0Hocd
• Wz 884
• 2’-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-propiophenonhydrochloride
• 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (9CI)
• Rytmonor
• 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanonhydroc
• 1-[2-(2-HYDROXY-3-[PROPYLAMINO]-PROPOXY)PHENYL]-3-PHENYL-1-PROPANONE HYDROCHLORIDE
• 2’-(2-hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenonehydrochloride
• PROPAFENONE HCL
• sa79
• Propiophenone, 2'-[2-hydroxy-3-(propylamino)propoxy]-3-phenyl-, hydrochloride (8CI)
• wz884

Propafenone Hydrochloride

CAS: 34183-22-7, 54063-53-5

Fórmula: C₂₁H₂₇NO₃·HCl

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 377.91

Ref: 3B-P2301

Propafenone Hydrochloride

CAS: 34183-22-7

Cor e Forma: Neat

Ref: 61-FOR0405.00

PROPAFENONE HYDROCHLORIDE CRS

CAS: 34183-22-7

PROPAFENONE HYDROCHLORIDE CRS

Fórmula: C₂₁H₂₈ClNO₃

Cor e Forma: White. Colourless Crystals. Powder.

Peso molecular: 377.9049

Ref: 41-Y0000455

Propafenone Hydrochloride

CAS: 34183-22-7

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Fórmula: C₂₁H₂₇NO₃·ClH

Cor e Forma: Colorless White Powder

Peso molecular: 377.17577

Ref: 45-1570304

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

CAS: 34183-22-7

Fórmula: C₂₁H₂₈ClNO₃

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 377.9049

Ref: IN-DA00391F

Propafenone HCl

CAS: 34183-22-7

Fórmula: C₂₁H₂₇NO₃·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 341.45 36.46

Ref: 4Z-P-1512

Propafenone hydrochloride

CAS: 34183-22-7

Propafenone hydrochloride

Pureza: ≥98%

Peso molecular: 377.9g/mol

Ref: 54-BUP17652

1-[2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl]-3-Phenylpropan-1-One Hydrochloride

CAS: 34183-22-7

1-[2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl]-3-Phenylpropan-1-One Hydrochloride

Pureza: 98%

Peso molecular: 377.9g/mol

Ref: 54-OR1030254

Propafenone hydrochloride, 10mM (in DMSO)

CAS: 34183-22-7

Propafenone hydrochloride, 10mM (in DMSO)

Pureza: ≥98%

Peso molecular: 377.9g/mol

Ref: 54-BUP20003

Propafenone hydrochloride

CAS: 34183-22-7

Fórmula: C₂₁H₂₇NO₃·HCl

Pureza: 98.0 - 102.0 % (C21H27NO3 · HCl, dried basis)

Cor e Forma: Colourless crystals or white crystalline powder

Peso molecular: 377.90

Ref: 7W-GP3270

Propafenone Hydrochloride

CAS: 34183-22-7

Fórmula: C₂₁H₂₇NO₃·ClH

Cor e Forma: Neat

Peso molecular: 377.90

Ref: 86-MM0405.00

Propafenone hydrochloride

CAS: 34183-22-7

Fórmula: C₂₁H₂₇NO₃·ClH

Cor e Forma: Neat

Peso molecular: 377.90

Ref: 04-C16385000

Propafenone hydrochloride

CAS: 34183-22-7

Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial.

Fórmula: C₂₁H₂₇NO₃·HCl

Pureza: 99.67%

Cor e Forma: White Solid

Peso molecular: 377.9

Ref: TM-T6955

Propafenone Hydrochloride

Produto Controlado

CAS: 34183-22-7

Applications Sodium channel blocker. Antiarrhythmic (class IC).
References Hollmann, M., et al.: Arzneim.-Forsch., 33, 763 (1983), Bryson, H. M., et al.:Drugs, 45, 85 (1993), Rae, A. P., et al.: Am. J. Cardiol., 82, 59N (1998),

Fórmula: C₂₁H₂₇NO₃·ClH

Cor e Forma: White To Off-White

Peso molecular: 377.90

Ref: TR-P757500

Propafenone HCl - Bio-X ™

CAS: 34183-22-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₂₁H₂₈ClNO₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 377.9 g/mol

Ref: 3D-BP300114

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

CAS: 34183-22-7

Fórmula: C₂₁H₂₈ClNO₃

Pureza: 95%+

Peso molecular: 377.91

Ref: 10-F358367

Propafenone HCl

CAS: 34183-22-7

Propafenone HCl is a class Ia antiarrhythmic drug that is used to treat atrial fibrillation and other cardiac arrhythmias. It has a high solubility in water, which makes it suitable for intravenous administration. The binding constants of propafenone to the cardiac muscle and myocardial cells are relatively high. This drug has also been shown to be safe in pediatric patients with congestive heart failure. Propafenone HCl has been shown to have an adverse effect on some people, causing serious side effects such as congestive heart failure or hypersensitivity reactions.

Fórmula: C₂₁H₂₈ClNO₃

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 377.9 g/mol

Ref: 3D-FP27186