CAS 343-65-7

Quinurenina

Descrição:

Quinurenina é um metabolito endógeno do aminoácido triptofano, desempenhando um papel significativo em vários processos biológicos. Está principalmente envolvido na via de Quinurenina, que é crucial para o metabolismo do triptofano e a produção de vários compostos neuroativos. Quinurenina é caracterizado por sua estrutura, que inclui um anel de indol e uma cadeia lateral contendo um ácido carboxílico e um grupo amina. Este composto exibe uma variedade de atividades biológicas, incluindo efeitos neuroprotetores e neurotóxicos, dependendo de sua concentração e da presença de outros metabolitos na via de Quinurenina. Quinurenina também está implicado na regulação da resposta imunológica e tem sido estudado por seu papel potencial em vários distúrbios neurológicos, incluindo depressão e doenças neurodegenerativas. Sua solubilidade em água e em vários solventes orgânicos permite diversas aplicações na pesquisa bioquímica. Além disso, Quinurenina pode ser medido em amostras biológicas, tornando-se um biomarcador valioso para avaliar condições metabólicas e patológicas.

Fórmula: C₁₀H₁₂N₂O₃

InChI: InChI=1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)

Chave InChI: InChIKey=YGPSJZOEDVAXAB-UHFFFAOYSA-N

SMILES: C(CC(C(O)=O)N)(=O)C1=C(N)C=CC=C1

Sinónimos:

• 2-Amino-4-(2-Aminophenyl)-4-Oxobutanoic Acid
• 2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid
• 3-Anthraniloyl-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-alanine
• 3-Anthraniloylalanine
• <span class="text-smallcaps">DL</span>-Kynurenine
• Alanine, 3-anthraniloyl-
• Benzenebutanoic acid, α,2-diamino-γ-oxo-
• Beta-Anthraniloyl-Alpha-Alanine
• Dl-Kynurenine Free Base
• Kynurenin
• Kynurenine

DL-Kynurenine

CAS: 343-65-7

Fórmula: C₁₀H₁₂N₂O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 208.2139

Ref: IN-DA00BYZG

Kynurenine

CAS: 343-65-7

Fórmula: C₁₀H₁₂N₂O₃

Peso molecular: 208.22

Ref: 4Z-K-008003

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS: 343-65-7

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

Pureza: ≥98%

Peso molecular: 208.21g/mol

Ref: 54-BUP14242

DL-Kynurenine

CAS: 343-65-7

Ref: 7W-GM2236

DL-Kynurenine-d7 (2,3,3-d3 ;ring-d4)

CAS: 343-65-7

Pureza: 99 atom % D

Peso molecular: 215.26

Ref: 3U-D8212

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS: 343-65-7

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid: a vasodilator, immunomodulator, neuromodulator, niacin precursor, and potential cancer biomarker.

Fórmula: C₁₀H₁₂N₂O₃

Pureza: 99.04% - 99.66%

Cor e Forma: Solid

Peso molecular: 208.21

Ref: TM-T3011

rac Kynurenine

Produto Controlado

CAS: 343-65-7

Applications A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan.
References Swartz, K., et al.: J. Neurosci., 10, 2965 (1990), Hasegawa, H., et al.: Anal. Bioanal. Chem., 377, 886 (2003), Tsai, Y., et al.: Anal. Biochem., 319, 34 (2003), Mitsuhashi, S., et al.: Anal. Chim. Acta, 584, 315 (2007),

Fórmula: C₁₀H₁₂N₂O₃

Cor e Forma: Neat

Peso molecular: 208.21

Ref: TR-K661000

rac Kynurenine-d4 Trifluoroacetic Acid Salt (Major)

Produto Controlado

CAS: 343-65-7

Stability Hygroscopic
Applications rac Kynurenine-d4 Trifluoroacetic Acid Salt is the isotope labelled analog of rac Kynurenine (K661000) which is a tryptophan metabolite.
References Swartz, K., et al.: J. Neurosci., 10, 2965 (1990), Hasegawa, H., et al.: Anal. Bioanal. Chem., 377, 886 (2003), Tsai, Y., et al.: Anal. Biochem., 319, 34 (2003), Mitsuhashi, S., et al.: Anal. Chim. Acta, 584, 315 (2007),

Fórmula: C₁₀H₈D₄N₂O₃•x(C₂HF₃O₂)

Cor e Forma: Neat

Peso molecular: 212.2411402

Ref: TR-K661003

DL-Kynurenine, free base

CAS: 343-65-7

DL-Kynurenine, free base is an amino acid that is a product of the normal catabolic pathway for tryptophan. It is also present in some foods and may be produced endogenously from tryptophan or kynurenine. DL-Kynurenine is used as a polymerase chain reaction (PCR) substrate to detect enterovirus RNA and has been shown to be effective against bowel disease in vitro. DL-Kynurenine has been studied as a potential pharmacological agent for the treatment of inflammatory diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, and psoriasis. DL-Kynurenine binds to toll-like receptor 4 (TLR4) and inhibits picolinic acid production by macrophages. This leads to decreased matrix metalloproteinase activity and energy metabolism, which may have a protective effect on neuronal death by reducing oxidative stress.

Fórmula: C₁₀H₁₂N₂O₃

Pureza: Min. 95%

Peso molecular: 208.20 g/mol

Ref: 3D-FK172296

DL-Kynurenine, free base

CAS: 343-65-7

DL-Kynurenine is a versatile building block, useful in the synthesis of complex compounds. The compound has been used as a reagent, and as a speciality chemical with high quality. DL-Kynurenine can be used as a starting material for the synthesis of other chemicals, such as pharmaceuticals or pesticides. It can also be used as an intermediate to produce drugs that are useful for the treatment of Alzheimer's disease, Huntington's disease, Parkinson's disease and schizophrenia. DL-Kynurenine is also an effective scaffold for drug design.

Fórmula: C₁₀H₁₂N₂O₃

Pureza: Min. 95 Area-%

Peso molecular: 208.22 g/mol

Ref: 3D-K-9000

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS: 343-65-7

Fórmula: C₁₀H₁₂N₂O₃

Pureza: 98%

Peso molecular: 208.217

Ref: 10-F223134