CAS 3556-56-7

Éster 4-nitrofenil de N-[(fenilmetoxi)carbonil]-L-tirosina

Descrição:

Éster 4-nitrofenil de N-[(fenilmetoxi)carbonil]-L-tirosina, com número CAS 3556-56-7, é um composto químico que pertence à classe de derivados de aminoácidos. Apresenta uma estrutura de backbone de tirosina, que é um aminoácido aromático conhecido por seu papel na síntese de proteínas e como precursor de neurotransmissores. O composto é caracterizado pela presença de um grupo protetor fenilmetoxicarbonilo (Pmc), que é comumente usado na síntese de peptídeos para proteger o grupo amino do aminoácido. Além disso, o grupo éster de 4-nitrofenila contribui para sua reatividade, tornando-o útil em várias reações químicas, particularmente na síntese de peptídeos e outras moléculas orgânicas complexas. O composto é tipicamente um sólido à temperatura ambiente e pode apresentar solubilidade em solventes orgânicos. Suas propriedades, como ponto de fusão, solubilidade e reatividade, podem variar com base nas condições específicas e na pureza da amostra. No geral, este composto é significativo na síntese orgânica e na bioquímica, particularmente no desenvolvimento de produtos farmacêuticos e bioconjugados.

Fórmula: C₂₃H₂₀N₂O₇

InChI: InChI=1S/C23H20N2O7/c26-19-10-6-16(7-11-19)14-21(24-23(28)31-15-17-4-2-1-3-5-17)22(27)32-20-12-8-18(9-13-20)25(29)30/h1-13,21,26H,14-15H2,(H,24,28)/t21-/m0/s1

Chave InChI: InChIKey=WUHIFOXZYIQZFP-NRFANRHFSA-N

SMILES: [C@H](CC1=CC=C(O)C=C1)(C(OC2=CC=C(N(=O)=O)C=C2)=O)NC(OCC3=CC=CC=C3)=O

Sinónimos:

• 4-nitrophenyl N-[(benzyloxy)carbonyl]tyrosinate
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• N-CBZ-L-Tyrosine-p-nitrophenyl ester N-Carbobenzyloxy-L-tyrosine-p-nitrophenyl ester
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine 4-nitrophenyl ester
• N-α-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• NSC 88489
• Tyrosine, N-carboxy-, N-benzyl p-nitrophenyl ester, <span class="text-smallcaps">L</span>-
• Z-Tyr-ONp
• p-Nitrophenyl N-benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine
• α-N-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• Tyrosine, N-carboxy-, N-benzyl p-nitrophenyl ester, L-
• N-α-Carbobenzoxy-L-tyrosine p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]-L-tyrosine 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)-L-tyrosine p-nitrophenyl ester

Z-Tyr-Onp

CAS: 3556-56-7

Fórmula: C₂₃H₂₀N₂O₇

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 436.4141

Ref: IN-DA00BYAK

Z-Tyr-Onp

CAS: 3556-56-7

Z-Tyr-Onp

Pureza: 98%

Peso molecular: 436.41g/mol

Ref: 54-OR1015469

Z-L-tyrosine 4-nitrophenyl ester

CAS: 3556-56-7

Z-L-tyrosine 4-nitrophenyl ester is a synthetic, inactivated amide that binds to the active site of enzyme, preventing its enzymatic activity. It prevents the formation of clots by cleaving the clotting factors and is used in blood transfusions. Z-L-tyrosine 4-nitrophenyl ester has been shown to inhibit the synthesis of surfactant and is used as an antiseptic. This drug can be prepared by reacting L-tyrosine with nitrophenol (NO2) in the presence of a base such as sodium hydroxide or potassium carbonate, followed by purification on sephadex g-100 columns. The product is then treated with hydrostatic pressure to remove any unreacted starting materials. This drug also has a sedimentation rate of about 1.5 x 10^6 cm/s.

Fórmula: C₂₃H₂₀N₂O₇

Pureza: Min. 95%

Cor e Forma: White/Off-White Solid

Peso molecular: 436.41 g/mol

Ref: 3D-FT47319

Z-Tyr-ONp

CAS: 3556-56-7

Z-Tyr-ONp is a synthetic, water soluble, non-toxic fibrinogen activator. It has been shown to be effective at low concentrations in the activation of fibrinogen and in the prevention of clotting. Z-Tyr-ONp hydrolyzes fibrinogen to form fibrin clots, which are needed for blood coagulation. This process is mediated by the enzyme alpha-thrombin and is dependent on calcium ions. Z-Tyr-ONp also exhibits surfactant properties that allow it to stabilize micelles that contain lipase enzymes and bile salts, which are required for digestion of dietary fats. The presence of lipase enzymes can enhance the proteolytic activity of Z-Tyr-ONp and increase its ability to dissolve clots.

Fórmula: C₂₃H₂₀N₂O₇

Pureza: Min. 95%

Peso molecular: 436.41 g/mol

Ref: 3D-SYN-3016