CAS 355806-00-7

1,1-Dimetiletil (3R,5S,6E)-7-[4-(4-fluorofenil)-6-(1-metiletil)-2-[metil(metilsulfonil)amino]-5-pirimidinil]-3,5-diidroxi-6-heptenoato

Descrição:

1,1-Dimetiletil (3R,5S,6E)-7-[4-(4-fluorofenil)-6-(1-metiletil)-2-[metil(metilsulfonil)amino]-5-pirimidinil]-3,5-diidroxi-6-heptenoato, com número CAS 355806-00-7, é um composto orgânico complexo caracterizado por sua intrincada estrutura molecular, que inclui múltiplos grupos funcionais como hidroxila, moieties de pirimidina e sulfonamida. Este composto é notável por sua estereoquímica, apresentando centros quirais específicos que contribuem para sua atividade biológica. A presença de um grupo fluorofenila sugere interações potenciais com alvos biológicos, tornando-o de interesse na química medicinal. Sua espinha dorsal de heptenoato indica que pode exibir insaturação, o que pode influenciar sua reatividade e estabilidade. A solubilidade do composto, o ponto de fusão e outras propriedades físicas dependeriam de suas interações moleculares e da presença de substituintes. No geral, esta substância provavelmente será estudada por suas propriedades farmacológicas, particularmente no contexto do desenvolvimento de medicamentos e aplicações terapêuticas.

Fórmula: C₂₆H₃₆FN₃O₆S

InChI: InChI=1S/C26H36FN3O6S/c1-16(2)23-21(13-12-19(31)14-20(32)15-22(33)36-26(3,4)5)24(17-8-10-18(27)11-9-17)29-25(28-23)30(6)37(7,34)35/h8-13,16,19-20,31-32H,14-15H2,1-7H3/b13-12+/t19-,20-/m1/s1

Chave InChI: InChIKey=IJHZGLLGELSZAF-OKLSWEBGSA-N

SMILES: C(=C/[C@H](C[C@H](CC(OC(C)(C)C)=O)O)O)\C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2

Sinónimos:

• (+)-(3r, 5s)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesulfonylamino)Pyrimidin-5-Yl]-(3, 5)-Dihydroxy-6(E)-Heptenoate
• (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
• (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid,dimethylethyl ester
• 1,1-Dimethylethyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoate
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-
• Rosuvastatin calcium intermediate R-3
• Rosuvastatin tert-Butyl Ester
• tert-Butyl rosuvastatin
• tert-Butyl(6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate
• tert-butyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate

6-Heptenoic acid,7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-

CAS: 355806-00-7

Fórmula: C₂₆H₃₆FN₃O₆S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 537.6439

Ref: IN-DA00I726

Rosuvastatin tert-butyl ester

CAS: 355806-00-7

Rosuvastatin tert-butyl ester

Pureza: 98%

Peso molecular: 537.64g/mol

Ref: 54-PC111420

Rosuvastatin tert-Butyl Ester

CAS: 355806-00-7

Fórmula: C₂₆H₃₆FN₃O₆S

Cor e Forma: White To Off-White Solid

Peso molecular: 537.65

Ref: 4Z-R-099

Rosuvastatin Impurity 37

CAS: 355806-00-7

Fórmula: C₂₆H₃₇N₃O₆S

Cor e Forma: White To Off-White Solid

Peso molecular: 519.66

Ref: 4Z-R-0995

Rosuvastatin tert-Butyl Ester

Produto Controlado

CAS: 355806-00-7

Stability Hygroscopic
Applications Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.
References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),

Fórmula: C₂₆H₃₆FN₃O₆S

Cor e Forma: Neat

Peso molecular: 537.64

Ref: TR-R700540

(3R,5S,6E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(METHANESULFONYL) METHYLAMINO]PYRIMIDIN-5-YL]-3,5-DIHYDROXYHEPT-6-ENOIC ACID TERT-BUTYL ESTER

CAS: 355806-00-7

Pureza: 98%

Peso molecular: 537.6500244

Ref: 10-F835716

Rosuvastatin Acid t-Butyl Ester

CAS: 355806-00-7

Fórmula: C₂₆H₃₆FN₃O₆S

Peso molecular: 537.65

Ref: ST-EA-CP-R1080

Tert-Butyl Rosuvastatin

CAS: 355806-00-7

Tert-Butyl Rosuvastatin is a synthetic statin. It has a high melting point, which can be used to separate the optical isomers. The tert-butyl group of the rosuvastatin molecule makes it soluble in organic solvents such as tetrahydrofuran, while the ester side chain makes it hydrolysis resistant. Tert-Butyl Rosuvastatin was found to be free of impurities and had a purity of at least 99% by liquid chromatography analysis. Analysis by mass spectrometry confirmed that no other alkali metal ions were present at greater than 0.1%.

Fórmula: C₂₆H₃₆FN₃O₆S

Pureza: Min. 95%

Peso molecular: 537.65 g/mol

Ref: 3D-FT35382