CAS 356-12-7

Fluocinolona

Descrição:

Fluocinolona é um corticosteroide sintético usado principalmente por suas propriedades anti-inflamatórias e imunossupressoras, tornando-o eficaz no tratamento de várias condições de pele, como eczema, psoríase e dermatite. É classificado como um corticosteroide tópico potente, o que significa que é projetado para aplicação diretamente na pele. A estrutura química de Fluocinolona inclui uma espinha dorsal esteroide fluorada, que aumenta sua potência e eficácia em comparação com corticosteroides não fluorados. Normalmente aparece como um pó cristalino branco a off-white e é pouco solúvel em água, mas solúvel em solventes orgânicos. Fluocinolona atua inibindo a liberação de mediadores inflamatórios e reduzindo a proliferação de células da pele, aliviando assim sintomas como vermelhidão, coceira e inchaço. Devido à sua potência, é importante usar Fluocinolona sob supervisão médica para evitar potenciais efeitos colaterais, como afinamento da pele ou absorção sistêmica, especialmente com o uso prolongado. Como com todos os medicamentos, diretrizes adequadas de dosagem e aplicação devem ser seguidas para garantir segurança e eficácia.

Fórmula: C₂₆H₃₂F₂O₇

InChI: InChI=1/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1

Chave InChI: InChIKey=WJOHZNCJWYWUJD-IUGZLZTKSA-N

SMILES: C(COC(C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H]

Sinónimos:

• (6α,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
• 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregna-1,4-diene-3,20-dione deriv.
• Biscosal
• Dermaplus
• Flucetonide
• Flucinar
• Fluocinolide
• Fluocinolide acetate
• Fluocinolone acetonide 21-acetate
• Fluocinolone acetonide acetate
• Fluocinonid
• Fluocinonide
• Fluocinonido
• Lidex
• Lidex E
• Metosyn
• Nsc 101791
• Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, 21-acetate
• Straderm
• Topsym
• Topsymin
• Topsyn
• Topsyne
• Vanos
• 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl acetate
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-
• 2-(4b,12-difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl)-2-oxoethyl acetate
• Fluocinonideacetate
• Lonide
• Fluocinolone Acetonide EP Impurity M
• FLUOCINOMIDE
• Fluocinonide Acetonide
• Fluocinonide USP/EP/BP
• Fluorocarbon acetate
• lidexe
• fluocinolideacetate
• Gelisyn
• 1,4-PREGNADIEN-6-ALPHA, 9-ALPHA-DIFLUORO-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE 21-ACETATE
• Lidemol
• Fluocinolone Acetonide Impurity 13 (Fluocinolone Acetonide EP Impurity M）(Fluocinonide)
• Cortalar
• pregna-1,4-diene-3,20-dione, 6-alpha, 9-difluoro-11-beta,16-alpha,17,21-tetrahy droxy-, cyclic 17-acetal with acetone, 21-acetate flucinar fluocinolide fluocinolide acetate fluocinolone acetonide 21-acetate fluocinolone acetonide acetate fluocinonide lidex e Fluocinonide acetate 21-Acatyloxy-6,9-diflulro-11-hydroxy-16,17-[(1-methyl-ethylidene)bis(oxy)]pregna-1,4-di-ene-3,20-dione
• droxy-,cyclic17-acetalwithacetone,21-acetate
• Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, 21-acetate (7CI, 8CI)
• Fluocinoide acetonide
• Fluocinonide, Micronized
• Fluocinonide Solution, 100ppm
• 2-chloroethoxy(diphenyl)phosphine
• FLUOCINONIDE ACETONIDE 21-ACETATE
• Fluoxetine acetate
• Fluocinonide (100 mg)
• fluocinoloneacetonideacetate
• Fluocinonide RS
• pregna-1,4-diene-3,20-dione,6-alpha,9-difluoro-11-beta,16-alpha,17,21-tetrahy
• FLUOCINONIDE,MICRONIZED,USP

Fluocinolone Acetonide EP Impurity M

CAS: 356-12-7

Fórmula: C₂₆H₃₂F₂O₇

Peso molecular: 494.5

Ref: ST-EA-CP-F56024

Fluocinonide

CAS: 356-12-7

Fluocinonide

Fórmula: C₂₆H₃₂F₂O₇

Pureza: 98.1%

Cor e Forma: White

Peso molecular: 494.21161

Ref: 47-489

Fluocinonide

CAS: 356-12-7

Halogenated derivatives of adrenal cortical hormones

Fórmula: C₂₆H₃₂F₂O₇

Cor e Forma: White Cream Powder

Peso molecular: 494.21161

Ref: 45-1276001

Fluocinonide

CAS: 356-12-7

Fluocinonide

Pureza: ≥98%

Peso molecular: 494.52g/mol

Ref: 54-BUP15757

Fluocinonide (Fluocinolone Acetonide EP Impurity M)

CAS: 356-12-7

Fórmula: C₂₆H₃₂F₂O₇

Cor e Forma: White To Off-White Solid

Peso molecular: 494.53

Ref: 4Z-F-271

Fluocinonide, micronised

CAS: 356-12-7

Fórmula: C₂₆H₃₂F₂O₇

Pureza: ≤ 1.0%

Cor e Forma: White powder

Peso molecular: 494.52

Ref: 7W-GP3657

Fluocinonide

Produto Controlado

CAS: 356-12-7

Fórmula: C₂₆H₃₂F₂O₇

Cor e Forma: Neat

Peso molecular: 494.52

Ref: 04-C13729000

Fluocinonide

CAS: 356-12-7

Cor e Forma: Neat

Ref: 86-MM3001.00

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

Produto Controlado

CAS: 105102-22-5, 1177-87-3, 124-94-7, 13609-67-1, 14484-47-0, 1524-88-5, 2135-17-3, 2152-44-5, 25122-46-7, 25122-57-0, 3093-35-4, 33564-31-7, 356-12-7, 378-44-9, 3801-06-7, 3870-07-3, 426-13-1, 4419-39-0, 50-02-2, 50-03-3, 50-04-4, 50-23-7, 50-24-8, 51022-69-6, 51333-22-3, 514-36-3, 53-06-5, 5534-09-8, 5593-20-4, 57524-89-7, 66734-13-2, 67-78-7, 73771-04-7, 76-25-5, 80474-14-2, 83-43-2, 987-24-6

Cor e Forma: Mixture

Ref: 04-A50000094ME

Fluocinonide

CAS: 356-12-7

Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.

Fórmula: C₂₆H₃₂F₂O₇

Pureza: 98.33% - 99.70%

Cor e Forma: Solid

Peso molecular: 494.52

Ref: TM-T6502

Fluocinonide RS

CAS: 356-12-7

Cor e Forma: White

Ref: 2K-1132000021

Fluocinolone acetonide acetate

CAS: 356-12-7

Applications Glucocorticoid; anti-inflammatory.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Brunmair, B., et al.: J. Pharmacol. Exp. Therap., 311, 109 (2004), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),

Fórmula: C₂₆H₃₂F₂O₇

Cor e Forma: White To Off-White

Peso molecular: 494.52

Ref: TR-F455805

Fluocinonide

CAS: 356-12-7

Fluocinonide is a synthetic corticosteroid that inhibits the production of inflammatory mediators and has anti-inflammatory effects. It is used to treat mild to moderate eczema, psoriasis, and other skin disorders. Fluocinonide is also used topically to relieve eye irritation caused by seasonal allergies or infections. This drug has minimal toxicity and does not cause major side effects in the gastrointestinal tract. Fluocinonide is a biocompatible polymer with antimicrobial properties. It binds to bacterial cell walls and disrupts their structure, causing them to rupture. The reaction solution can be used for wastewater treatment as it is able to remove organic matter from water, including bacteria and viruses.

Fórmula: C₂₆H₃₂F₂O₇

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 494.54 g/mol

Ref: 3D-FF08245