CAS 356068-93-4

5-((Z)-(5-Fluoro-2-oxoindolin-3-ilideno)metil)-2,4-dimetil-1H-pirrol-3-carboxílico ácido

Descrição:

5-((Z)-(5-Fluoro-2-oxoindolin-3-ilideno)metil)-2,4-dimetil-1H-pirrol-3-carboxílico ácido, com número CAS 356068-93-4, é um composto orgânico sintético caracterizado por sua estrutura complexa, que inclui um anel de pirrol, um grupo funcional ácido carboxílico e uma moiety de indolinona. A presença do átomo de flúor sugere potencial para atividade biológica aprimorada ou propriedades físico-químicas alteradas. Este composto pode exibir propriedades interessantes, como solubilidade em solventes orgânicos, estabilidade moderada em condições padrão e reatividade potencial devido ao grupo ácido carboxílico. Sua estrutura única pode conferir atividades biológicas específicas, tornando-o um candidato para pesquisa farmacêutica, particularmente no desenvolvimento de novos agentes terapêuticos. A síntese e caracterização do composto normalmente envolveriam técnicas como espectroscopia de RMN, espectrometria de massas e possivelmente cristalografia de raios X para confirmar sua estrutura molecular e pureza. No geral, este composto representa uma classe de compostos heterocíclicos que são de grande interesse em química medicinal e desenvolvimento de medicamentos.

Fórmula: C₁₆H₁₃FN₂O₃

InChI: InChI=1/C16H13FN2O3/c1-7-13(18-8(2)14(7)16(21)22)6-11-10-5-9(17)3-4-12(10)19-15(11)20/h3-6,18H,1-2H3,(H,19,20)(H,21,22)/b11-6-

SMILES: Cc1c(/C=C\2/c3cc(ccc3N=C2O)F)[nH]c(C)c1C(=O)O

Sinónimos:

• 1H-pyrrole-3-carboxylic acid, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-
• 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
• (Z)-5-[(5-Fluoro-2-oxoindolin-3-ylidene)methyl]-2,4-dimethylpyrrole-3-carboxylic Acid
• 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl...
• (3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-on
• Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid
• (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxylic acid
• (3Z)-3-[(3,5-DiMethyl-4-carboxy-1H-pyrrol-2-yl)Methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one
• 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Pureza: 95.0%

Cor e Forma: Solid

Peso molecular: 300.28900146484375

Ref: 10-F238886

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Fórmula: C₁₆H₁₃FN₂O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 300.2844

Ref: IN-DA0037KR

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Ref: 7W-GX6190

(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Pureza: 98%

Peso molecular: 300.289g/mol

Ref: 54-PC99839

5-[(Z)-(5-Fluoro-2-oxo-indolin-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid

Produto Controlado

CAS: 356068-93-4

Fórmula: C₁₆H₁₃FN₂O₃

Cor e Forma: Neat

Peso molecular: 300.28

Ref: 86-MM3568.04

Sunitinib Impurity 13

CAS: 356068-93-4

Fórmula: C₁₆H₁₃FN₂O₃

Peso molecular: 300.3

Ref: ST-EA-CP-S42036

5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl is an inhibitor of protein kinase. It inhibits the activity of protein kinase C (PKC) and also has immunosuppressive properties. 5-(2,4-Dimethylphenyl)-5-[(5-fluoroindolinylidene)methyl]pyrrole is a white to off white crystalline powder that belongs to the class of pyrroles. It has been shown to be a vasotropic agent by binding to the alpha 1 beta 1 integrin receptor on vascular smooth muscle cells. This drug binds to aminophospholipids in plasma and can cause osteopathic lesions when injected into bone tissue. 5-(2,4-Dimethylphenyl)-5-[(5-fluoroindolinylidene)methyl]pyrrole has been shown to have antiinflammatory effects

Fórmula: C₁₆H₁₃FN₂O₃

Pureza: Min. 95%

Peso molecular: 300.28 g/mol

Ref: 3D-FF106180

Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid

Produto Controlado

CAS: 356068-93-4

Applications Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid is an impurity of Sunitinib (S819995), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Antineoplastic.
References Sun, L., et al.: J. Med. Chem., 46, 1116 (2003); Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003); Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004); Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004)

Fórmula: C₁₆H₁₃FN₂O₃

Cor e Forma: Neat

Peso molecular: 300.28

Ref: TR-D367070

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65586 and the CAS number is 356068-93-4.

Fórmula: C₁₆H₁₃FN₂O₃

Cor e Forma: Solid

Peso molecular: 300.289

Ref: TM-T65586