CAS 35730-78-0

Cinaropicrina

Descrição:

Cinaropicrina é um composto natural classificado como uma lactona sesquiterpênica, encontrado principalmente em alcachofras (Cynara scolymus) e outros membros da família Asteraceae. É conhecido por seu sabor amargo e muitas vezes está associado às propriedades medicinais da planta. A estrutura química de Cinaropicrina apresenta um anel de lactona, contribuindo para sua atividade biológica. Este composto exibe vários efeitos farmacológicos, incluindo propriedades anti-inflamatórias, antioxidantes e potenciais anticancerígenas, tornando-o de interesse tanto na ciência dos alimentos quanto na pesquisa medicinal. Além disso, Cinaropicrina tem sido estudado por seu papel na estimulação do apetite e na ajuda à digestão, o que se alinha com os usos tradicionais das alcachofras. Seu número CAS, 35730-78-0, é um identificador único que facilita a catalogação e o estudo deste composto na literatura científica. No geral, Cinaropicrina representa um exemplo significativo de como os produtos naturais podem influenciar a saúde e a nutrição.

Fórmula: C₁₉H₂₂O₆

InChI: InChI=1S/C19H22O6/c1-8-5-14(24-18(22)9(2)7-20)16-11(4)19(23)25-17(16)15-10(3)13(21)6-12(8)15/h12-17,20-21H,1-7H2/t12-,13-,14-,15-,16+,17+/m0/s1

Chave InChI: InChIKey=KHSCYOFDKADJDJ-NQLMQOPMSA-N

SMILES: C=C1[C@@]2([C@@]3([C@@]([C@@H](OC(C(CO)=C)=O)CC(=C)[C@@]2(C[C@@H]1O)[H])(C(=C)C(=O)O3)[H])[H])[H]

Sinónimos:

• 2-(Hydroxymethyl)-2-propenoic Acid (3aR,4S,6aR,8S,9aR,9bR)-Dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl Ester
• 2-Propenoic acid, 2-(hydroxymethyl)-, (3aR,4S,6aR,8S,9aR,9bR)-dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno(4,5-b)furan-4-yl ester
• 2-Propenoic acid, 2-(hydroxymethyl)-, dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester, [3aR-(3aα,4α,6aα,8β,9aα,9bβ)]-
• 68370-45-6
• Azuleno[4,5-b]furan, 2-propenoic acid deriv.
• Cynaropicrin
• Cynaropikrin
• 2-Hydroxymethylpropenoic acid (3aR,4S,6aβ,9aβ,9bα)-dodecahydro-8α-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester
• CYNAROPICRIN(SH)
• [(3aR,4S,6aR,8S,9aR,9bR)-8-hydroxy-3,6,9-trimethylidene-2-oxo-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-4-yl] 2-(hydroxymethyl)prop-2-enoate
• 2-methylolacrylic acid [(3aR,4S,6aR,8S,9aR,9bR)-8-hydroxy-2-keto-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-4-yl] ester

Cynaropicrin

CAS: 35730-78-0

Cynaropicrin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₉H₂₂O₆

Pureza: (HPLC) ≥95%

Cor e Forma: Powder

Peso molecular: 346.38

Ref: 11-3820

Cynaropicrin

CAS: 35730-78-0

Cynaropicrin

Pureza: ≥95%

Peso molecular: 346.37g/mol

Ref: 54-BUP00309

Cynaropicrin

CAS: 35730-78-0

Cynaropicrin is a sesquiterpene lactone found in artichoke with anti-hepatitis C and trypanosome activity and inhibits NF-κB activation.

Fórmula: C₁₉H₂₂O₆

Pureza: 96.15%

Cor e Forma: Solid

Peso molecular: 346.37

Ref: TM-TN1543

Cynaropicrin

CAS: 35730-78-0

Cynaropicrin is a potent activator of the AhR-Nrf2-Nqo1 pathway, and could therefore be applied to prevention of UVB-induced photo aging; it may be a potential anticancer agent against some leukocyte cancer cells such as lymphoma or leukemia, through pro-apoptotic activity. Cynaropicrin shows in vivo activity against Trypanosoma brucei. Cynaropicrin possesses immunomodulatory effects on cytokine release, nitric oxide production and immunosuppressive effects. Cynaropicrin also has anti-inflammatory effects, it may participate in the inflammatory response by inhibiting the production of inflammatory mediators and the proliferation of lymphocytes and its inhibitory effect is mediated through conjugation with sulphydryl groups of target protein(s).

Fórmula: C₁₉H₂₂O₆

Pureza: 95%~99%

Peso molecular: 346.379

Ref: BP-BP0443

Cynaropicrin

CAS: 35730-78-0

Fórmula: C₁₉H₂₂O₆

Pureza: ≥ 97.0%

Cor e Forma: White to beige powder

Peso molecular: 346.38

Ref: 7W-GY8068

Cynaropicrin

CAS: 35730-78-0

Lactone

Fórmula: C₁₉H₂₂O₆

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 346.38

Ref: 5G-89619

Cynaropicrin - Cynara cardunculus (artichoke)

CAS: 35730-78-0

Cynaropicrin is a sesquiterpene lactone, which is a bioactive compound derived from Cynara cardunculus, commonly known as the artichoke. The source of this compound is primarily the leaves and flowering parts of the plant, which have been traditionally used in herbal medicine. Cynaropicrin exhibits its biological activity through the inhibition of various inflammatory pathways, particularly by modulating the NF-κB signaling pathway, which is crucial in the regulation of immune response and inflammation.

Fórmula: C₁₉H₂₂O₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 346.37 g/mol

Ref: 3D-XC160151