CAS 3599-32-4

Verde de indocianina

Descrição:

Verde de indocianina (ICG) é um corante sintético utilizado principalmente em diagnósticos médicos, particularmente em oftalmologia e imagens cardiovasculares. É caracterizado por sua cor verde escura e forte absorção na região do infravermelho próximo do espectro eletromagnético, tornando-o especialmente útil para imagens de fluorescência. A estrutura química do ICG inclui uma espinha dorsal de corante cianina, que contribui para suas propriedades ópticas únicas. O ICG é solúvel em água e tem um perfil de toxicidade relativamente baixo, o que aumenta sua adequação para aplicações clínicas. Após a administração, ele se liga a proteínas plasmáticas, permitindo uma visualização eficaz do fluxo sanguíneo e da perfusão tecidual. Sua rápida eliminação da corrente sanguínea, principalmente pelo fígado, é outra característica notável. Além disso, o ICG é utilizado em várias aplicações além da imagem, incluindo a avaliação da função hepática e a orientação de procedimentos cirúrgicos. No geral, suas propriedades distintas fazem de Verde de indocianina uma ferramenta valiosa tanto em ambientes diagnósticos quanto terapêuticos.

Fórmula: C₄₃H₄₇N₂NaO₆S₂

InChI: InChI=1/C43H48N2O6S2.Na/c1-42(2)36-26-24-32-18-10-12-20-34(32)40(36)44(28-14-16-30-52(46,47)48)38(42)22-8-6-5-7-9-23-39-43(3,4)37-27-25-33-19-11-13-21-35(33)41(37)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1/rC43H47N2NaO6S2/c1-42(2)36-26-24-32-18-10-12-20-34(32)40(36)44(28-14-16-30-53(47,48)49)38(42)22-8-6-5-7-9-23-39-43(3,4)37-27-25-33-19-11-13-21-35(33)41(37)45(39)29-15-17-31-54(50,51)52-46/h5-13,18-27H,14-17,28-31H2,1-4H3

Chave InChI: InChIKey=AANGVCDSLQANGQ-UHFFFAOYSA-N

SMILES: CC1(C)C2=C([N+](CCCCS(=O)(=O)[O-])=C1C=CC=CC=CC=C3N(CCCCS(=O)(=O)O)C4=C(C3(C)C)C=5C(C=C4)=CC=CC5)C=CC=6C2=CC=CC6.[Na]

Sinónimos:

• 1H-Benz[e]indolium, 2-[7-[1,1-dimethyl-3-(4-sulfobutyl)benz[e]indolin-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, hydroxide, inner salt, sodium salt
• 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (1:1)
• 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, hydroxide, inner salt, sodium salt
• 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt
• 2-{7-[1,3-Dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]hepta-1,3,5-trienyl}-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium, hydroxyde, sel interne, sel de sodium
• 4,5-Benzoindotricarbocyanine
• 4-[(2Z)-2-[(2Z,4E,6Z)-7-[3,3-dimethyl-1-(4-sulfonatobutyl)benzo[g]indol-1-ium-2-yl]hepta-2,4,6-trienylidene]-3,3-dimethyl-benzo[g]indol-1-yl]butylsulfonyloxysodium
• Cardio Green
• HWD Indocyanine Green
• ICG
• Indocyanin green
• Ir-125
• Natrium-2-[7-[3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolin-2-yliden]hepta-1,3,5-trien-1-yl]-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
• Nk 2611
• Nk 2612
• Opthagreen
• Sacarosa, Bruta (De Cana)
• Saccharose, Brut (De Canne)
• So 270
• Sodium 2-(7-(3,3-Dimethyl-1-(4-Sulfonatobutyl)Benz(E)Indolin-2-Ylidene)Hepta-1,3,5-Trien-Y-1-Yl)-3,3-Dimethyl-1-(4-Sulfonatobutyl)Benz[E]Indolinium
• Sodium 2-(7-(3,3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
• Ujoviridin
• Wofaverdin
• sodium 4-(2-{7-[1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indolium-2-yl]hepta-2,4,6-trien-1-ylidene}-1,1-dimethyl-1,2-dihydro-3H-benzo[e]indol-3-yl)butane-1-sulfonate
• 4-(2-[7-[1,1-DIMETHYL-3-(4-SULFO-BUTYL)-1H-BENZO[E]INDOL-2-YL]-HEPTA-2,4,6-TRIENYLIDENE]-1,1-DIMETHYL-BENZO[E]INDOLIUM-3-YL)-BUTANE-1-SULFONIC ACID SODIUM SALT
• )-1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,innersalt,
• CARDIOGREEN
• BIS-[1-(4-SULFOBUTYL)-3,3-DIMETHYL-4,5-BENZOINDOLINYLIDEN-2]-HEPTAMETHINECYANINE-BETAINE-SODIUM SALT (INDOCYANINEGREEN, CARDIOGREEN)
• FOXGREEN
• IC GREEN
• INDOCYANINE GREEN
• ,innersalt,sodiumsalt(9ci)

Indocyanine Green

CAS: 3599-32-4

Synthetic organic coloring matter,nesoi

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Cor e Forma: Green Brown Blue Powder

Peso molecular: 774.27732

Ref: 45-1340009

1H-Benz[e]indolium,2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodiumsalt

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 774.9629

Ref: IN-DA00I74W

Indocyanine green

CAS: 3599-32-4

Indocyanine green

Pureza: ≥98%

Peso molecular: 774.96g/mol

Ref: 54-BUP17455

Cardio-Green

CAS: 3599-32-4

Cardio-Green

Pureza: 97%

Peso molecular: 774.96g/mol

Ref: 54-OR1012625

Indocyanine Green

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂O₆S₂·Na

Peso molecular: 751.98 22.99

Ref: 4Z-I-134001

Cardiogreen, 95%, USP grade

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Pureza: 90.0 - 105.0 % (dried basis)

Cor e Forma: Dark green to brown crystalline powder

Peso molecular: 774.96

Ref: 7W-GT1101

Indocyanine green

CAS: 3599-32-4

Indocyanine green (Cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics.

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Pureza: ≥98%

Cor e Forma: Green To Green With A Brown Cast Powder

Peso molecular: 774.96

Ref: TM-T14875

Indocyanine Green-d12

CAS: 3599-32-4

Fórmula: C₄₃H₃₅D₁₂N₂O₆S₂·Na

Peso molecular: 764.05 22.99

Ref: 4Z-I-134002

Cardiogreen

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Pureza: ≥ 90.0%

Cor e Forma: Dark green powder

Peso molecular: 774.96

Ref: 7W-GT1409

Indocianine Green RS

CAS: 3599-32-4, 7681-82-5

Cor e Forma: Dark Greenish Blue Solid Powder

Ref: 2K-2001000021

Indocyanine Green (~90%)

Produto Controlado

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂O₆S₂·Na

Pureza: ~90%

Cor e Forma: Neat

Peso molecular: 774.96

Ref: TR-I697000

Indocyanine green

CAS: 3599-32-4

Indocyanine green is a fluorescent dye with a variety of applications in medical imaging. It has been used to diagnose and evaluate the activity of cancer cells and brain functions. Indocyanine green has also been used as an angiographic agent for diagnosis of solid tumours. In addition, it can be used to evaluate liver function and the blood flow in the brain. The biological properties of indocyanine green have not yet been fully elucidated, but it is known that it binds to hepatocyte-like cells in culture and is found at high levels in human serum. This dye shows fluorescence when bound to DNA or RNA, which indicates its possible use as a molecular probe for detecting carcinoma cells. 
Indocyanine green is a STT3B inhibitor and has been shown to prevent α-amanitin toxicity in mice (Wang et al, 2023). This means it could be a possible antidote to poisoning by Amanita, such as death cap mushroom Amanita phalloides, which is the cause of over 90% of fatal mushroom poisoning.

Fórmula: C₄₃H₄₇N₂O₆S₂·Na

Pureza: (%) Min. 95%

Cor e Forma: Green Powder

Peso molecular: 774.96 g/mol

Ref: 3D-FI10558

Indocyanine Green >d6

Produto Controlado

CAS: 3599-32-4

Applications It is the labeled analogue of Indocyanine Green (I697000), a tricarbocyanine type of dye with infrared absorbing properties that can be used as a diagnostic aid (blood volume determination, cardiac output, hepatic function).
References Papageorgiou, P., et al.: Br. J. Dermatol., 142, 973 (2000), Dreno, B., et al.: Dermatology, 203, 135 (2001), Gollnick, H., et al.: Drugs, 63, 1579 (2003), Seaton, E., et al.: Lancet, 362, 1347 (2003),

Fórmula: C₇H₁₄N₂O

Cor e Forma: Neat

Peso molecular: NA

Ref: TR-I697003

Indocyanine Green

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Cor e Forma: Light yellow to Amber to Dark green powder to crystal

Peso molecular: 774.97

Ref: 3B-I0535

Indocyanine green

CAS: 3599-32-4

Pureza: 95%

Peso molecular: 774.97

Ref: 10-F868901