CAS 37248-47-8

Validamicina A

Descrição:

Validamicina A é um antibiótico e fungicida de ocorrência natural, derivado principalmente da fermentação da bactéria Streptomyces hygroscopicus. É caracterizado por sua estrutura complexa, que inclui uma porção de açúcar e um componente de peptídeo cíclico, contribuindo para sua atividade biológica. Validamicina A exibe fortes propriedades antifúngicas, particularmente contra vários patógenos de plantas, tornando-o valioso em aplicações agrícolas para proteção de culturas. Seu mecanismo de ação envolve a inibição da síntese de quitina nas paredes celulares dos fungos, o que é crucial para seu crescimento e sobrevivência. Além disso, Validamicina A tem sido estudado por seu potencial uso no controle de certas infecções bacterianas e como biopesticida devido à sua baixa toxicidade para organismos não-alvo. O composto é solúvel em água e exibe estabilidade sob várias condições ambientais, o que aumenta sua utilidade em formulações agrícolas. No geral, Validamicina A representa um avanço significativo no desenvolvimento de agentes de controle de pragas ambientalmente amigáveis.

Fórmula: C₂₀H₃₅NO₁₃

InChI: InChI=1S/C20H35NO13/c22-3-6-1-8(12(26)15(29)11(6)25)21-9-2-7(4-23)19(17(31)13(9)27)34-20-18(32)16(30)14(28)10(5-24)33-20/h1,7-32H,2-5H2/t7-,8+,9+,10-,11-,12+,13+,14-,15+,16+,17-,18-,19-,20+/m1/s1

Chave InChI: InChIKey=JARYYMUOCXVXNK-CSLFJTBJSA-N

SMILES: O([C@@H]1[C@@H](CO)C[C@H](N[C@H]2C=C(CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O

Sinónimos:

• ((1S,4R,5S,6S)-4,5,6-trihydroxy-3-hydroxymethylcyclohex-2-
• (1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl beta-D-glucopyranoside
• (1S,2S,3R,4R,6S)-2,3-dihydroxy-6-(hydroxymethyl)-4-{[(4S,5R,6R)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl beta-D-glucopyranoside
• (1S-(1a,4a,5B,6a))-1,5,6-Trideoxy-3-O-B-D-glucopyranosyl-5-
• (1S-(1alpha,4alpha,5beta,6alpha))-1,5,6-trideoxy-4-O-beta-D-
• (hydroxymethyl)-1-((4,5,6-trihydroxy-3-(hydroxymethyl)-2-
• (hydroxymethyl)-2-cyclohexen-1-yl)amino)-D-chiro-inositol
• 1,5,6-Trideoxy-4-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-<smallcap>D</span>-chiro-inositol
• 1L-(1,3,4/2,6)-2,3-Dihydroxy-6-hydromethyl-4-((1S,4R,5S,6S)-
• 1L-(1,3,4/2,6)-2,3-Dihydroxy-6-hydroxymethyl-4-
• 2,3-Dihydroxy-6-(Hydroxymethyl)-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Cyclohexyl Hexopyranoside
• 4,5,6-trihydroxy-3-hydroxymethylcyclohex-2-
• <span class="text-smallcaps">D</smallcap>-chiro-Inositol, 1,5,6-trideoxy-4-O-β-<smallcap>D</span>-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-
• <span class="text-smallcaps">D</smallcap>-chiro-Inositol, 1,5,6-trideoxy-4-O-β-<smallcap>D</span>-glucopyranosyl-5-(hydroxymethyl)-1-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-, [1S-(1α,4α,5β,6α)]-
• Cepex 10SL
• D-1,5,6-Trideoxy-3-O-beta-D-glucopyranosyl-5-
• Jinganmycin A
• Jinggang
• Jinggangmycin
• Jinggangmycin A
• Validacin
• Validamycin
• Validamycin A
• cyclohexen-1-yl)amino)-D-chiroinositol
• cyclohexen-1-yl)amino)-d-chiro-inositol
• enylamino)cyclohexyl beta-D-glucopyranoside
• glucopyranosyl-5-(hydroxymethyl)-1-((4,5,6-trihydroxy-3-
• D-chiro-Inositol, 1,5,6-trideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-, [1S-(1α,4α,5β,6α)]-
• 1,5,6-Trideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol

Validamycin

CAS: 37248-47-8

Fórmula: C₂₀H₃₅NO₁₃

Pureza: %

Cor e Forma: Solid

Peso molecular: 497.4908

Ref: IN-DA007A5W

Validamycin A

CAS: 37248-47-8

Fórmula: C₂₀H₃₅NO₁₃

Pureza: ≥ 60.0%

Cor e Forma: Off-white to light yellow powder

Peso molecular: 497.50

Ref: 7W-GA4672

Validamycin A

CAS: 37248-47-8

Validamycin A

Pureza: ≥98%

Peso molecular: 497.49g/mol

Ref: 54-BUP21397

Validamycin A

CAS: 37248-47-8

Validamycin A is an antibiotic and fungicide that inhibits the alginate enzyme trehalase Rhizoctonia solani, reversible inhibitor of tyrosinase.

Fórmula: C₂₀H₃₅NO₁₃

Pureza: 98.84%

Cor e Forma: White Powder

Peso molecular: 497.49

Ref: TM-T38268

Validamycin A

CAS: 37248-47-8

Fórmula: C₂₀H₃₅NO₁₃

Peso molecular: 497.49

Ref: 4Z-V-046007

Validamycin A Sulfate salt (Technical grade)

CAS: 37248-47-8

Applications Validamycin A (>70%) Hydrochloride Salt is a metabolite of Validamycin A (>70%) (V943430) which is an antibiotic fungicide that inhibits trehalase activity in plants, insects, and fungi.

Fórmula: C₂₀H₃₅NO₁₃·xH₂SO₄

Pureza: >70%

Cor e Forma: Off-White To Light Brown

Peso molecular: 497.4908

Ref: TR-V943435

Validamycin A

CAS: 37248-47-8

Validamycin A is an antibiotic and fungicide with action as a trehalase inhibitor, disrupting carbohydrate metabolism in fungi and is used for controlling fungal diseases like sheath blight in rice and damping-off in cucumbers.

Fórmula: C₂₀H₃₅NO₁₃

Pureza: Min. 92 Area-%

Cor e Forma: White Powder

Peso molecular: 497.49 g/mol

Ref: 3D-AV59477

VALIDAMYCIN

CAS: 37248-47-8

Pureza: 60+%

Peso molecular: 497.493988

Ref: 10-F826985

Validamycin A (>70%) Hydrochloride

CAS: 37248-47-8

Applications Validamycin A is an antibiotic fungicide that inhibits trehalase activity in plants, insects, and fungi.

Fórmula: C₂₀H₃₅NO₁₃·xHCl

Pureza: >70%

Cor e Forma: Neat

Peso molecular: 497.4908

Ref: TR-V943430