CAS 37682-72-7

L-Valinamida, N2-[[[(1S)-1-carboxi-2-feniletil]amino]carbonil]-L-arginil-N-[4-[(aminoiminometil)amino]-1-formilbutil]-, cloridrato (1:2)

Descrição:

L-Valinamida, N2-[[[(1S)-1-carboxi-2-feniletil]amino]carbonil]-L-arginil-N-[4-[(aminoiminometil)amino]-1-formilbutil]-, cloridrato (1:2) é um composto orgânico complexo caracterizado por sua estrutura multifuncional, que inclui derivados de aminoácidos e uma forma de sal hidroclorídrico. Esta substância apresenta uma combinação de uma espinha dorsal de L-valinamida e um fragmento de L-arginina, indicando seu potencial papel em sistemas biológicos, particularmente na síntese de peptídeos ou como um intermediário farmacêutico. A presença de múltiplos grupos funcionais, como ácidos carboxílicos, aminas e iminas, sugere que pode exibir diversas propriedades de reatividade e solubilidade. A forma hidroclorídica melhora sua estabilidade e solubilidade em ambientes aquosos, tornando-a adequada para várias aplicações em química medicinal. Além disso, a estereoquímica do composto, particularmente a configuração (1S), é crucial para sua atividade biológica, influenciando interações com alvos biológicos. No geral, a estrutura intrincada e a diversidade funcional deste composto o posicionam como uma entidade significativa no estudo de moléculas bioativas e agentes terapêuticos.

Fórmula: C₂₇H₄₄N₁₀O₆·2ClH

InChI: InChI=1S/C27H44N10O6.2ClH/c1-16(2)21(23(40)34-18(15-38)10-6-12-32-25(28)29)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17;;/h3-5,8-9,15-16,18-21H,6-7,10-14H2,1-2H3,(H,34,40)(H,37,39)(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43);2*1H

Chave InChI: InChIKey=YAHXZYICKJUJEO-UHFFFAOYSA-N

SMILES: C(C(NC(C(NC(CCCNC(=N)N)C=O)=O)C(C)C)=O)(NC(NC(CC1=CC=CC=C1)C(O)=O)=O)CCCNC(=N)N.Cl

Sinónimos:

• <span class="text-smallcaps">L</smallcap>-Valinamide, N²-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-<smallcap>L</span>-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, dihydrochloride
• <span class="text-smallcaps">L</smallcap>-Valinamide, N²-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-<smallcap>L</span>-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2)
• Antipain dihydrochloride
• L-Valinamide, N(sup 2)-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, dihydrochloride
• N-({(1S)-4-[(diaminomethylidene)amino]-1-[(N-{4-[(diaminomethylidene)amino]-1-formylbutyl}-L-valyl)carbamoyl]butyl}carbamoyl)phenylalanine dihydrochloride
• L-Valinamide, N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, dihydrochloride
• L-Valinamide, N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2)

Antipain dihydrochloride

CAS: 37682-72-7

Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases. This Thermo Scientific brand product was originally part of the Alfa

Fórmula: C₂₇H₄₄N₁₀O₆•2HCl

Cor e Forma: White, Powder

Peso molecular: 677.6

Ref: 02-J63680

Antipain dihydrochloride

CAS: 37682-72-7

Antipain dihydrochloride

Cor e Forma: White To Pale Yellow Powder

Peso molecular: 677.62g/mol

Ref: 54-BIA0201

Antipain dihydrochloride

CAS: 37682-72-7

Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes with analgesic activity.

Fórmula: C₂₇H₄₆Cl₂N₁₀O₆

Pureza: 95%

Cor e Forma: White To Off-White Powder

Peso molecular: 677.62

Ref: TM-T26637

Antipain dihydrochloride

CAS: 37682-72-7

Fórmula: C₂₇H₄₄N₁₀O₆₂HCl

Peso molecular: 677.60

Ref: 7W-GL6582

Antipain (Synthetic)

CAS: 37682-72-7

Antipain (supplied as the HCl salt) is a cytosolic and bound form of antipain. It binds to ATP-binding cassette transporter proteins, which are involved in the transport of substances across cell membranes, and inhibits their enzymatic activity. Antipain 2HCI also has inhibitory properties on enzymes such as DNA polymerase II and pyruvate kinase. It has been shown to have an effect on biochemical properties such as protein synthesis, enzyme activities, and polymerase chain reactions. This drug has been shown to be effective in preventing myocardial infarcts and cellular apoptosis by inhibiting the release of cytochrome c from mitochondria. Antipain 2HCI may also have some anti-inflammatory effects due to its inhibition of prostaglandin synthesis.

Fórmula: C₂₇H₄₄N₁₀O₆·2HCl

Pureza: Min. 95%

Peso molecular: 604.7 g/mol

Ref: 3D-IAP-3996-PI

Antipain dihydrochloride

CAS: 37682-72-7

Antipain 2HCI is a cytosolic and bound form of antipain. It binds to ATP-binding cassette transporter proteins, which are involved in the transport of substances across cell membranes, and inhibits their enzymatic activity. Antipain 2HCI also has inhibitory properties on enzymes such as DNA polymerase II and pyruvate kinase. It has been shown to have an effect on biochemical properties such as protein synthesis, enzyme activities, and polymerase chain reactions. This drug has been shown to be effective in preventing myocardial infarcts and cellular apoptosis by inhibiting the release of cytochrome c from mitochondria. Antipain 2HCI may also have some anti-inflammatory effects due to its inhibition of prostaglandin synthesis.

Fórmula: C₂₇H₄₄N₁₀O₆•(HCl)₂

Pureza: Min. 95%

Peso molecular: 677.62 g/mol

Ref: 3D-FA29612