CAS 37691-11-5

Antidor

Descrição:

Antidor, com o número CAS 37691-11-5, é um peptídeo sintético que funciona principalmente como um inibidor de proteases. É derivado do produto natural da bactéria *Streptomyces* e é conhecido por sua capacidade de inibir várias proteases de serina e cisteína, tornando-se uma ferramenta valiosa na pesquisa bioquímica. Antidor é frequentemente utilizado em estudos envolvendo degradação de proteínas, sinalização celular e apoptose, pois pode ajudar a elucidar os papéis das proteases nesses processos. A substância é tipicamente caracterizada por seu peso molecular relativamente baixo e características estruturais específicas que permitem que se ligue às proteases de forma eficaz. Em ambientes de laboratório, Antidor é geralmente manuseado como um pó e é solúvel em soluções aquosas, o que facilita sua aplicação em vários protocolos experimentais. As fichas de dados de segurança recomendam precauções padrão de laboratório ao manusear este composto, assim como qualquer substância química. No geral, Antidor serve como um reagente importante no estudo das enzimas proteolíticas e suas implicações biológicas.

Fórmula: C₂₇H₄₄N₁₀O₆

InChI: InChI=1S/C27H44N10O6/c1-16(2)21(23(40)34-18(15-38)10-6-12-32-25(28)29)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17/h3-5,8-9,15-16,18-21H,6-7,10-14H2,1-2H3,(H,34,40)(H,37,39)(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43)

Chave InChI: InChIKey=SDNYTAYICBFYFH-UHFFFAOYSA-N

SMILES: C(C(NC(C(NC(CCCNC(=N)N)C=O)=O)C(C)C)=O)(NC(NC(CC1=CC=CC=C1)C(O)=O)=O)CCCNC(=N)N

Sinónimos:

• <span class="text-smallcaps">L</smallcap>-Valinamide, N²-[[(1-carboxy-2-phenylethyl)amino]carbonyl]-<smallcap>L</span>-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-
• Antipain
• Ccris 3605
• L-Valinamide, N(sup 2)-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-
• L-Valinamide, N2-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-
• N²-[[(1-Carboxy-2-phenylethyl)amino]carbonyl]-<span class="text-smallcaps">L</smallcap>-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-<smallcap>L</span>-valinamide
• N~2~-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}-N~5~-(diaminomethylidene)-L-ornithyl-N-{(2S)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}-L-valinamide
• N2-(((1-Carboxyphenethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-L-valinamide
• N2-[[(1-Carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-valinamide

Antipain

CAS: 37691-11-5

A reversible inhibitor of Ser and Cys proteases with an activity spectrum comparable to leupeptin. Antipain inhibited transformation of NIH3T3 cells after transfection with an activated H-ras oncogene (Cox et al.). Vaccari et al. used antipain for evaluating the role of proteases in the process of malignant transformation of BALB/c 3T3 cells.

Fórmula: C₂₇H₄₄N₁₀O₆

Cor e Forma: Yellowish Powder

Peso molecular: 604.71

Ref: 01-4030290

Antipain

CAS: 37691-11-5

Fórmula: C₂₇H₄₄N₁₀O₆

Peso molecular: 604.70

Ref: 7W-GA6508

Antipain

CAS: 37691-11-5

Antipain, from Actinomycetes, blocks proteases and combats MNNG-induced genetic changes.

Fórmula: C₂₇H₄₄N₁₀O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 604.713

Ref: TM-T14295

Antipain

CAS: 37691-11-5

Antipain is a protease inhibitor, which is derived from microbial sources. It inhibits serine and cysteine proteases through the formation of a reversible covalent complex with the active site of the enzyme. This interaction effectively prevents the proteolytic activity of these enzymes, thereby modulating various biological processes.The primary application of Antipain is in biochemical research where it is utilized to study protease function and regulation. By inhibiting specific proteases, researchers can investigate protein degradation pathways and decipher complex signaling mechanisms. Additionally, Antipain is used experimentally to inhibit protease activity in cell lysates, thereby preserving protein integrity during sample preparation. Its specificity for serine and cysteine proteases makes it a valuable tool for differentiating between proteolytic activities in various biological samples.

Fórmula: C₂₇H₄₄N₁₀O₆net

Pureza: Min. 95%

Peso molecular: 604.7 g/mol

Ref: 3D-IAP-4062

Antipain

CAS: 37691-11-5

Antipain is a proteolytic enzyme that hydrolyzes peptide bonds in proteins. It is a member of the papain family of proteases and has been shown to activate peptides and inhibit ion channels, both of which are important for cell biology research. Antipain, an inhibitor of protein synthesis, is also used as a research tool in cell biology and biochemistry.

Fórmula: C₂₇H₄₄N₁₀O₆

Pureza: Min. 95%

Peso molecular: 604.7 g/mol

Ref: 3D-IAP-4062-V