CAS 3810-74-0

Sulfato de estreptomicina

Descrição:

Sulfato de estreptomicina é um antibiótico aminoglicosídeo derivado da bactéria Streptomyces griseus. É utilizado principalmente para tratar várias infecções bacterianas, particularmente aquelas causadas por Mycobacterium tuberculosis, tornando-se significativo na terapia da tuberculose. O composto é caracterizado por sua capacidade de inibir a síntese de proteínas bacterianas ao se ligar à subunidade ribossomal 30S, o que interrompe o processo de tradução. Sulfato de estreptomicina é um pó cristalino branco a ligeiramente amarelo que é solúvel em água, o que facilita sua administração por injeção. Possui uma fórmula molecular que reflete sua estrutura complexa, incluindo múltiplos grupos amino e hidroxila. A forma sulfato melhora sua solubilidade e estabilidade. Efeitos colaterais comuns incluem ototoxicidade e nefrotoxicidade, exigindo monitoramento cuidadoso durante o tratamento. Sulfato de estreptomicina também é notável por seu papel no desenvolvimento de resistência a antibióticos, sublinhando a importância do uso criterioso em ambientes clínicos. No geral, continua sendo um agente crítico no arsenal contra certas infecções bacterianas, particularmente no contexto de cepas multirresistentes.

Fórmula: C₂₁H₃₉N₇O₁₂H₂O₄S

InChI: InChI=1S/C21H39N7O12.H2O4S/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;1-5(2,3)4/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);(H2,1,2,3,4)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;/m0./s1

Chave InChI: InChIKey=CFCMMYICHMLDCC-RMIBZTJPSA-N

SMILES: S(=O)(=O)(O)O.O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(C=O)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3

Sinónimos:

• 1,1'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (1:1)
• 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (2:3)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N¹,N³-bis(aminoiminomethyl)-, sulfate (2:3)
• Ag Streptomycin
• Agri-Strep
• Agrimycin 17
• Agrimycin sulfate
• Ambistryn
• Ambistryn S
• D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
• D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3)
• FireWall (pesticide)
• Flare 72SP
• Hortocyna
• KeyStrepto
• N'',N'''''-[(1R,2R,3S,4R,5R,6S)-4-({(2xi)-5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-threo-pentofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (salt)
• N'',N'''''-[(1S,2S,3R,4S,5S,6R)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-formyl-α-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (2:3) (salt)
• O-2-Deoxy-2-(Methylamino)-Alpha-L-Glucopyranosyl-(1->2)-O-5-Deoxy-3-C-Formyl-Alpha-L-Lyxofuranosyl-(1->4)-N,N'-Bis(Aminoiminomethyl)-Streptamine Sulfate (2:3)
• O-2-Deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-c-formyl-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-D-streptamine sulfate (2:3)
• Plantomycin
• Strepto
• Streptobrettin
• Streptomycin A sulfate
• Streptomycin Sesquisulfate
• Streptomycin Sulfate Sterile
• Streptomycin sesquisulphate
• Streptomycin sulphate
• Streptomycin, sulfate (2:3) (salt)
• Streptomycinsulfat
• Streptonex
• Strycin
• Sulfate de streptomycine
• Sulfato De Estreptomicina
• Vetstrep

Streptomycin sulfate, Antibiotic for Culture Media Use Only

CAS: 3810-74-0

Streptomycin sulfate is an antibiotic that inhibits the growth of bacteria by binding to the ribosomal subunit and interfering with protein synthesis. It is used in culture media for the production of human antibodies as well as in drug therapy for methicillin-resistant staphylococcus. Streptomycin sulfate has a high specific activity and low sensitivity, but it also has a low solubility in water. The active form of streptomycin sulfate is streptomycin A, which is produced by the addition of a phenyl ring to neomycin sulfate. In plant roots, streptomycin sulfate inhibits cyanogenic glycosides from being hydrolyzed into hydrogen cyanide (HCN) and benzaldehyde.

Fórmula: C₄₂H₈₄N₁₄O₃₆S₃

Peso molecular: 1,457.40 g/mol

Ref: 3D-S-8500

Streptomycin sulfate

CAS: 3810-74-0

Inhibitor of protein synthesis; aminoglycoside

Fórmula: (C₂₁H₃₉N₇O₁₂)₂•(H₂SO₄)₃

Pureza: Min. 720 Iu/Mg

Cor e Forma: White Off-White Powder

Peso molecular: 1,457.39 g/mol

Ref: 3D-AS01530

Streptomycin Sulphate (STM)

CAS: 3810-74-0

Fórmula: (C₂₁H₃₉N₇O₁₂)₂·3H₂SO₄

Cor e Forma: White to off - white, Crystalline powder, Clear, Pale yellow

Peso molecular: 1457.38

Ref: SR-91014

Streptomycin Sulphate for tissue culture

CAS: 3810-74-0

Fórmula: (C₂₁H₃₉N₇O₁₂)₂·3H₂SO₄

Cor e Forma: White to off - white, Crystalline powder, Clear, Pale yellow

Peso molecular: 1457.38

Ref: SR-62463