CAS 38243-03-7

R-Ginsenoside Rg3

Descrição:

R-Ginsenoside Rg3 é um composto natural derivado do ginseng, especificamente um tipo de ginsenosídeo, que são saponinas esteroides conhecidas por suas várias propriedades farmacológicas. É caracterizado por sua fórmula molecular, que reflete sua estrutura complexa, apresentando tipicamente uma espinha dorsal esteroide com moieties de açúcar. Rg3 existe em duas formas estereoisoméricas, sendo a forma R biologicamente ativa. Este composto é reconhecido por seus potenciais benefícios à saúde, incluindo efeitos anticancerígenos, anti-inflamatórios e neuroprotetores. Rg3 tem sido estudado por sua capacidade de modular várias vias biológicas, incluindo apoptose e proliferação celular, tornando-o de interesse tanto na medicina tradicional quanto na farmacologia moderna. Além disso, é frequentemente explorado no contexto de melhorar a função imunológica e a vitalidade geral. Sua solubilidade e estabilidade podem variar com base na formulação e nas condições, que são considerações importantes para sua aplicação em suplementos dietéticos e agentes terapêuticos. No geral, R-Ginsenoside Rg3 representa uma área significativa de pesquisa em química de produtos naturais e aplicações medicinais.

Fórmula: C₄₂H₇₂O₁₃

InChI: InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42+/m0/s1

Chave InChI: InChIKey=RWXIFXNRCLMQCD-CZIWJLDFSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@@H](CO)O5)CC4)[H])[H])[H]

Sinónimos:

• (20S)-Propanaxadiol
• (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxa
• (3Beta,12Beta)-12,20-Dihydroxydammar-24-En-3-Yl 2-O-Beta-D-Glucopyranosyl-Beta-D-Glucopyranoside
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranoside
• (5xi,8xi,9xi,12alpha,14beta,20R)-12,20-dihydroxylanost-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (8xi,9xi,12alpha,14beta,17alpha)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,14-tetramethylgonan-3-yl 2-O-[3-deoxy-3-(hydroxymethyl)-beta-D-glucopyranosyl]-beta-D-glucopyranoside
• 20(R)-Ginsenoside Rg₃
• 20(R)-Propanaxadiol
• 20(S)-Ginsenoside-Rg3
• 20R-Ginsenoside Rg3
• Beta-D-Glucopyranoside,(3-Beta,12-Beta)-12,20-Dihydroxydammar-24-En-3-Yl2-O-B
• Dammar-24-Ene-12-Beta,20-Diol,3-Beta-((2-O-Beta-D-Glucopyranosyl-Beta-D-Gluc
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-
• Eta-D-Glucopyranosyl-
• Ginsenoside rg3(R)
• Opyransoyl)Oxy)-
• R-Ginsenoside Rg₃
• beta-D-Glucopyranoside,(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
• 20(R)-Ginsenoside Rg3
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside

20(R)-Propanaxadiol

CAS: 38243-03-7

Ref: 7W-GC5327

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3

Pureza: ≥95%

Peso molecular: 785.01g/mol

Ref: 54-BUP00028

20(R)-Ginsenoside Rg3

CAS: 38243-03-7

20(R)-Ginsenoside Rg3 has shown multiple pharmacological activities and been considered as one of the most promising approaches for fatigue treatment, however, 20(R)-Ginsenoside Rg3 has a low bioavailability after oral administration in human, so, 20(R)-Rg3 can be by intranasal administration, the mechanism was related to the increase of the storage of hepatic glycogen, and the decrease of the accumulation of metabolite such as lactic acid and serum urea nitrogen.

Fórmula: C₄₂H₇₂O₁₃

Pureza: 95%~99%

Cor e Forma: White powder

Peso molecular: 785.025

Ref: BP-BP0040

20(R)-Ginsenoside Rg3

CAS: 38243-03-7

Fórmula: C₄₂H₇₂O₁₃

Pureza: >97.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 785.03

Ref: 3B-G0536

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) is a compound with anti-aging and antifatigue activities.

Fórmula: C₄₂H₇₂O₁₃

Pureza: 97.03% - 99.67%

Cor e Forma: Solid

Peso molecular: 785.01

Ref: TM-T3812

20(R)-Ginsenoside Rg3

Produto Controlado

CAS: 38243-03-7

Applications 20(R)-Ginsenoside Rg3 causes an inhibition of phosphatidylinositol 3-kinase/Akt activation that, in turn, results in modulations in Bcl-2 family proteins in such a way that the apoptosis of U87 cells are regulated. Elicits a significant inhibition of in vitro cell adhesion and invasion of U87 cells. in vitro stereoselective inhibition of ginsenosides toward UDP-glucuronosyltransferase isoforms and in vivo inhibition of tumor angiogenesis of lung cancer.
References Liu, Y., et al.: Chengdu Yixueyuan Xuebao, 9, 4 (2014); Liu, Y., et al.: Linchuang Junyi Zazhi, 42, 1138 (2014), Kim, D., et al.: Toxicol. Lett., 259, 1 92016); Geng, L., et al.: Zhonghua Zhongyiyao Zazhi, 29, 601 (2014)

Fórmula: C₄₂H₇₂O₁₃

Cor e Forma: Neat

Peso molecular: 785.01

Ref: TR-G387625

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3 is a triterpenoid saponin, which is a bioactive compound isolated from the root of Panax ginseng. This product is an integral part of traditional medicine and is now being extensively studied in modern pharmacological research. As a ginsenoside, Rg3 exerts its effects primarily by modulating cellular pathways, inhibiting angiogenesis, and inducing apoptosis in cancer cells.

Fórmula: C₄₂H₇₂O₁₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 785.01 g/mol

Ref: 3D-OG15964

20(R)-Ginsenoside Rg3-d6

Produto Controlado

CAS: 38243-03-7

Fórmula: C₄₂D₆H₆₆O₁₃

Cor e Forma: Neat

Peso molecular: 791.05

Ref: TR-G410288

20(R)-Propanaxadiol

CAS: 38243-03-7

Fórmula: C₄₂H₇₂O₁₃

Cor e Forma: Solid

Peso molecular: 785.0133

Ref: IN-DA00BXSG