CAS 3847-29-8

Lactobionato de eritromicina

Descrição:

Lactobionato de eritromicina é um antibiótico macrolídeo derivado da bactéria Saccharopolyspora erythraea. É utilizado principalmente para tratar várias infecções bacterianas, particularmente aquelas causadas por bactérias Gram-positivas e alguns organismos Gram-negativos. A substância é caracterizada por sua forma de sal lactobionato, que melhora sua solubilidade em água, tornando-a adequada para administração intravenosa. Lactobionato de eritromicina exibe um amplo espectro de atividade contra infecções do trato respiratório, infecções de pele e certas doenças sexualmente transmissíveis. Seu mecanismo de ação envolve a inibição da síntese de proteínas bacterianas ao se ligar à subunidade ribossômica 50S, impedindo assim o crescimento e a reprodução das bactérias. O composto é geralmente bem tolerado, embora possa causar efeitos colaterais gastrointestinais e tenha interações potenciais com outros medicamentos devido ao seu efeito sobre as enzimas hepáticas. Assim como com todos os antibióticos, o uso apropriado é crucial para prevenir o desenvolvimento de resistência aos antibióticos.

Fórmula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

InChI: InChI=1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1

Chave InChI: InChIKey=NNRXCKZMQLFUPL-WBMZRJHASA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3.[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)([C@@H]([C@H](C(O)=O)O)O)[C@@H](CO)O

Sinónimos:

• (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid - (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1) (non-preferred name)
• 4-O-beta-D-Galactopyranosyl-D-gluconic acid compd. with erythromycin
• <span class="text-smallcaps">D</smallcap>-Gluconic acid, 4-O-β-<smallcap>D</span>-galactopyranosyl-, compd. with erythromycin (1:1)
• D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, compd. with erythromycin (1:1) (9CI)
• Erythrocin Lactobionate IV
• Erythrocin lactobionate
• Erythromycin lactobionate (1:1) (salt)
• Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt)
• Erythromycin, 4-O-beta-D-galactopyranosyl-D-gluconate (salt)
• Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (1:1)
• Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (salt)
• Erythromycin. compd. with lactobionic acid
• Lactobionic acid, compd. with erythromycin (1:1)
• Oxacyclotetradecane, erythromycin deriv.
• Erythromycin, 4-O-β-D-galactopyranosyl-D-gluconate (1:1)

ERYTHROMYCIN LACTOBIONATE CRS

CAS: 3847-29-8

ERYTHROMYCIN LACTOBIONATE CRS

Fórmula: C₄₉H₈₉NO₂₅

Peso molecular: 1092.223

Ref: 41-Y0001848

Erythromycin Lactobionate

CAS: 3847-29-8

Erythromycin and its derivatives; salts thereof

Fórmula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

Cor e Forma: White Off-White Powder

Peso molecular: 1091.57237

Ref: 45-1247003

Erythromycin Lactobionate

CAS: 3847-29-8

Fórmula: C₄₉H₈₉NO₂₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1092.2227

Ref: IN-DA0079PQ

Erythromycin lactobionate

CAS: 3847-29-8

Erythromycin, a macrolide antibiotic, inhibits bacterial protein synthesis, effective against Streptococcus and Staphylococcus, and affects CYP3A4 metabolism.

Fórmula: C₄₉H₈₉NO₂₅

Cor e Forma: Solid

Peso molecular: 1092.233

Ref: TM-T37433

Erythromycin Lactobionate

Produto Controlado

CAS: 3847-29-8

Applications Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.
References Kiso, S. et al.: Anticanc. Res., 20, 2827 (2000); Broad, J. et al.: Brit. J. Pharm., 168,1859 (2013); Itoh, Z., et al.: Antimicrob. Agents Chemother., 26, 863(1984)

Fórmula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

Cor e Forma: Neat

Peso molecular: 1092.22

Ref: TR-E650040

Erythromycin iactobionate

CAS: 3847-29-8

Erythromycin lactobionate is a macrolide antibiotic, which is derived from the bacterium *Saccharopolyspora erythraea*. Its mode of action involves binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis and leading to the suppression of bacterial growth. This mechanism effectively targets gram-positive bacteria and some gram-negative bacteria, making it a crucial agent in the fight against various bacterial infections.

Fórmula: C₄₉H₈₇NO₂₄

Pureza: Min. 95%

Cor e Forma: White To Off-White Solid

Peso molecular: 1,074.21 g/mol

Ref: 3D-AE37145

Erythromycin lactobioate A

CAS: 3847-29-8

Fórmula: C₃₇H₆₇NO₁₃C₁₂H₂₂O₁₂

Peso molecular: 733.94 : 358.3

Ref: ST-EA-CP-E18027