CAS 3895-92-9

Cloreto de chelerythrine

Descrição:

O cloreto de chelerytrina é um sal de amônio quaternário derivado do alcaloide chelerytrina, que é encontrado principalmente em plantas da família Papaveraceae. É caracterizado por sua aparência cristalina amarela e é conhecido por sua atividade biológica, particularmente como um inibidor da proteína quinase C. O composto exibe uma variedade de propriedades farmacológicas, incluindo efeitos anti-inflamatórios e anticancerígenos, tornando-o de interesse na química medicinal. O cloreto de chelerytrina é solúvel em solventes orgânicos, mas tem solubilidade limitada em água, o que pode influenciar sua biodisponibilidade e aplicação em vários ambientes de pesquisa. Sua estrutura molecular apresenta um núcleo de benzofenantridina, contribuindo para suas propriedades químicas únicas e interações. Os dados de segurança indicam que, como muitos alcaloides, deve ser manuseado com cuidado devido à potencial toxicidade. No geral, o cloreto de chelerytrina serve como um composto valioso tanto em estudos farmacológicos quanto na exploração da química de produtos naturais.

Fórmula: C₂₁H₁₈ClNO₄

InChI: InChI=1/C21H19NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10,12H,11H2,1-3H3

Chave InChI: InChIKey=WEEFNMFMNMASJY-UHFFFAOYSA-M

SMILES: C[N+]=1C=2C(C=3C(C1)=C(OC)C(OC)=CC3)=CC=C4C2C=C5C(=C4)OCO5.[Cl-]

Sinónimos:

• 1,2-Dimethoxy-12-Methyl-6A,12-Dihydro[1,3]Benzodioxolo[5,6-C]Phenanthridine
• 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium chloride
• 1,2-Dimethoxy-12-methyl[1,3]dioxolo[4,5]benzo[1,2-c]phenanthridin-12-iumchlorid
• Broussonpapyrine chloride
• Chelerythrine Chlorid
• Chelerythrine chloride
• Chelerythrinium chloride
• Chlorure de 1,2-diméthoxy-12-méthyl[1,3]benzodioxolo[5,6-c]phénanthridin-12-ium
• NSC 646662
• [1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-, chloride
• [1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-, chloride (1:1)
• Chelerythrine chloride1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
• CHELERYTHRIN CL
• CHELERYTHRINE CHLORIDE(P)
• 1,2-diMethoxy-12-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-iuM chloride
• 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
• CHELERYTHRINE CHLORIDE(RG)
• TODDALIN CHLORIDE
• TODDALIN
• Chelerythrine Cl
• CHELERYTHRIN CHLORIDE
• 1,2-DIMETHOXY-12-METHYL[1,3]BENZODIOXOLO[5,6-C]PHENANTHRIDINIUM CHLORIDE
• chelerythrinehydrochloride
• Chelerythrine cloride
• 3)benzodioxolo(5,6-c)phenanthridinium,1,2-dimethoxy-12-methyl-(chloride
• 1,2-DIMETHOXY-12,[1,3]-BENZODIOXOLO[5,6-C]PHENANTHRIDINIUM CHLORIDE
• Chelerythrine chloride,98%

Chelerythrine Chloride

CAS: 3895-92-9

Fórmula: C₂₁H₁₈ClNO₄

Pureza: >97.0%(HPLC)

Cor e Forma: White to Yellow to Orange powder to crystal

Peso molecular: 383.83

Ref: 3B-C3584

Chelerythrine chloride, 99+%

CAS: 3895-92-9

A natural benzophenanthridine alkaloid. Inhibits protein kinase C. Induces apoptosis in leukemia cells This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aes

Fórmula: C₂₁H₁₈ClNO₄

Pureza: 99+%

Cor e Forma: Yellow, Solid

Peso molecular: 383.83

Ref: 02-J62906

Chelerythrine chloride

CAS: 3895-92-9

Chelerythrine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₂₁H₁₈NO₄Cl

Pureza: (HPLC) ≥95%

Cor e Forma: Powder

Peso molecular: 383.83

Ref: 11-1559

CHELERYTHRINE CHLORIDE CRS

CAS: 3895-92-9

CHELERYTHRINE CHLORIDE CRS

Ref: 41-Y0002288

1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridiniumchloride

CAS: 3895-92-9

Fórmula: C₂₁H₁₈ClNO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 383.8249

Ref: IN-DA0032KU

Chelerythrine chloride

CAS: 3895-92-9

Chelerythrine chloride

Pureza: ≥95%

Peso molecular: 383.83g/mol

Ref: 54-BUP13479

Chelerythrine chloride

CAS: 3895-92-9

Chelerythrine chloride

Fórmula: C₂₁H₁₈NO₄·Cl

Pureza: 98%

Cor e Forma: yellow powder

Peso molecular: 383.82g/mol

Ref: 54-BIC1008

Chelerythrine chloride

CAS: 3895-92-9

Fórmula: C₂₁H₁₈ClNO₄

Pureza: 95%~99%

Peso molecular: 383.828

Ref: BP-BP0341

Chelerythrine Chloride

CAS: 3895-92-9

Fórmula: C₂₁H₁₈NO₄·Cl

Peso molecular: 348.38 35.45

Ref: 4Z-C-484001

Chelerythrine chloride

CAS: 3895-92-9

Fórmula: C₂₁H₁₈ClNO₄

Pureza: ≥ 98.0%

Cor e Forma: Yellow to orange powder

Peso molecular: 383.82

Ref: 7W-GP2808

Chelerythrine chloride

CAS: 3895-92-9

Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to

Fórmula: C₂₁H₁₈ClNO₄

Pureza: 95% - 99.19%

Cor e Forma: Yellow To Orange Solid

Peso molecular: 383.83

Ref: TM-T3419

Chelerythrine chloride

CAS: 3895-92-9

Natural alkaloid

Fórmula: C₂₁H₁₈NO₄Cl

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 383.83

Ref: 5G-89896

Chelerythrine Chloride

CAS: 3895-92-9

Stability Hygroscopic
Applications Chelerythrine Chloride is a cell permeable protein kinase C (PKC) inhibitor.
References Song, L., et. al.: Brain Res., 1564, 52 (2014)

Fórmula: C₂₁H₁₈NO₄·Cl

Cor e Forma: Yellow

Peso molecular: 383.82

Ref: TR-C291880

Toddalin

CAS: 3895-92-9

Toddalin is a natural compound that is extracted from the leaves of Toddalia asiatica. It has been shown to inhibit the proliferation of certain types of cancer cells, including squamous carcinoma, through inhibition of protein synthesis. Toddalin is a basic protein with a molecular weight of around 4,000 Da, which can be found in both plants and animals. The physiological levels are unknown. This extract has been shown to have biological properties such as the ability to inhibit kinase activity and block adenosine receptors A3 (AR). It also inhibits cell factor-mediated activation of transcriptional factors such as NF-κB, AP-1, or p38 MAPK. Further research on this compound is needed to determine its effects on human health and ecological systems.

Fórmula: C₂₁H₁₈ClNO₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 383.82 g/mol

Ref: 3D-FT65648

Chelerythrine chloride

CAS: 3895-92-9

M01450 - Chelerythrine chloride

Fórmula: C₂₁H₁₈ClNO₄

Pureza: 98%

Peso molecular: 383.83

Ref: 10-M01450