CAS 39156-67-7

(5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-Tetradecahidro-5,13-diidroxi-9,15-dimetil-14-metileno-16-(fenilmetil)-2H-oxaciclotetradecino[2,3-d]isoindol-2,18(3H)-diona

Descrição:

A substância química com o nome "(5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-Tetradecahidro-5,13-diidroxi-9,15-dimetil-14-metileno-16-(fenilmetil)-2H-oxaciclotetradecino[2,3-d]isoindol-2,18(3H)-diona" e número CAS "39156-67-7" é um composto orgânico complexo caracterizado por sua intrincada estrutura policíclica e múltiplos estereocentros, que contribuem para sua configuração tridimensional específica. Este composto apresenta uma estrutura de tetradecahidro, indicando uma espinha dorsal de hidrocarboneto saturado, juntamente com grupos hidroxila que sugerem potencial para ligações de hidrogênio e reatividade. A presença de um grupo fenilmetila indica características aromáticas, que podem influenciar seu comportamento químico e interações. Além disso, os múltiplos grupos metila do composto e uma ponte metileno contribuem para sua hidrofobicidade geral e impedância estérica. Tais características estruturais podem conferir atividade biológica, tornando-o de interesse em química medicinal e farmacologia. Sua configuração única e grupos funcionais sugerem aplicações potenciais no desenvolvimento de medicamentos ou como sonda bioquímica.

Fórmula: C₂₉H₃₉NO₅

InChI: InChI=1/C29H39NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14,18-19,22-24,26-27,31,33H,3,7,9-10,13,15-17H2,1-2H3,(H,30,34)/b14-8+/t18-,19-,22+,23-,24-,26+,27+,29-/m0/s1

Chave InChI: InChIKey=WIULKAASLBZREV-RXPQEOCGSA-N

SMILES: O=C1[C@]23[C@]([C@H](CC4=CC=CC=C4)N1)([C@H](C)C(=C)[C@@H](O)[C@@]2(/C=C/C[C@H](C)CCC[C@@H](O)CCC(=O)O3)[H])[H]

Sinónimos:

• (11Z)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-tetradecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione
• (5R,9R,11E,12aS,13S,15R,15aR,16S,18aR)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-tetradecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione
• (5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-Tetradecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione
• (5R,9S,11E,12aS,13S,15R,15aR,16S,18aR)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-tetradecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione
• (5S,9R,11E,12aS,13S,15R,15aR,16S,18aR)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-tetradecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione
• (5S,9R,11E,12aS,13S,15S,15aS,16S,18aS)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-tetradecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione
• (5S,9S,11E,12aS,13S,15R,15aR,16S,18aR)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-tetradecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione
• 16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-tetradecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione
• 21,22-Dihydrochalasin B
• 21,22-Dihydrocytochalasan B
• 21,22-Dihydrocytochalasin B
• 21,22-Dihydrophomin
• 24-Oxa[14]cytochalasa-6(12),13-diene-1,23-dione, 7,20-dihydroxy-16-methyl-10-phenyl-, (7S,13E,16R,20R)-
• 2H-Oxacyclotetradecino[2,3-d]isoindole-2,18(3H)-dione, 4,5,6,7,8,9,10,12a,13,14,15,15a,16,17-tetradecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-
• Dihydrocytochalasin B
• 7(S),20(R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa(14)cytochalasa-6(12),13(E)-diene-1,23-dione
• CYTOCHALASIN B, DIHYDRO
• Dihidrocytochalasin B
• (7S,13E,16R,20R)-7,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13-diene-1,23-dione
• (7S,13E,16R,20R)-7β,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13-diene-1,23-dione
• DHCB

Dihydrocytochalasin B

CAS: 39156-67-7

Fórmula: C₂₉H₃₉NO₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 481.6237

Ref: IN-DA00BXFC

Dihydrocytochalasin B

CAS: 39156-67-7

Dihydrocytochalasin B

Cor e Forma: White Powder

Peso molecular: 481.62g/mol

Ref: 54-BID1004

Dihydrocytochalasin B

CAS: 39156-67-7

Fórmula: C₂₉H₃₉NO₅

Pureza: (HPLC) ≥ 98.0%

Cor e Forma: White powder

Peso molecular: 481.62

Ref: 7W-GL7061

Dihydrocytochalasin B

CAS: 39156-67-7

Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.

Fórmula: C₂₉H₃₉NO₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 481.62

Ref: TM-T11042