CAS 39178-35-3

Cloreto de isonicotinilo hidrocloreto

Descrição:

Cloreto de isonicotinilo hidrocloreto é um composto químico que pertence à classe dos cloretos de acilo, especificamente derivado do ácido isonicotínico. É caracterizado por sua reatividade devido à presença do grupo funcional cloreto de acilo, o que o torna um intermediário útil na síntese orgânica, particularmente na preparação de vários fármacos e agroquímicos. O composto geralmente aparece como um sólido branco a off-white e é solúvel em solventes orgânicos polares. É importante manusear Cloreto de isonicotinilo hidrocloreto com cuidado, pois pode ser corrosivo e pode liberar ácido clorídrico durante a hidrólise. O composto é frequentemente utilizado na síntese de derivados isonicotinoyl, que têm aplicações em química medicinal, particularmente no desenvolvimento de agentes anti-tuberculose e outros compostos terapêuticos. Devem ser observadas precauções de segurança ao trabalhar com esta substância, incluindo o uso de equipamentos de proteção individual adequados e trabalhar em uma área bem ventilada ou capela de exaustão.

Fórmula: C₆H₄ClNO·ClH

InChI: InChI=1S/C6H4ClNO.ClH/c7-6(9)5-1-3-8-4-2-5;/h1-4H;1H

Chave InChI: InChIKey=BNTRVUUJBGBGLZ-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C=1C=CN=CC1.Cl

Sinónimos:

• (Chlorocarbonyl)-4-(pyridinyl) monohydrochloride
• 4-(Chloroformyl)pyridinium hydrochloride
• 4-Nicotinoyl chloride hydrochloride
• 4-Pyridinecarbonyl chloride, hydrochloride
• 4-Pyridinecarbonyl chloride, hydrochloride (1:1)
• 4-Pyridinecarboxylic acid chloride hydrochloride
• 4-Pyridinoyl Chloride Hydrochloride
• Isonicotinic acid chloride hydrochloride
• Isonicotinoyl Chloride Hydrochloride
• Isonicotinoyl Chloride Hydrochloride, 95 %
• Isonicotinoyl Chloride Hydrochloride,Pyridine-4-Carbonyl Chloride
• IsonicotinoylchlorideHCl
• Isonicotinyl Chloride Hydrochloride
• Pyridine-4-Carbonyl Chloride Hydrochloride
• Pyridine-4-Carbonyl Chloride Hydrochloride (1:1)
• Pyridine-4-carbonylchlorideHCl
• Timtec-Bb Sbb003768

Isonicotinoyl chloride hydrochloride, 97%

CAS: 39178-35-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₆H₅Cl₂NO

Pureza: 97%

Cor e Forma: White to cream to pale brown or pale yellow, Crystalline powder

Peso molecular: 178.01

Ref: 02-A10863

Isonicotinoyl chloride hydrochloride

CAS: 39178-35-3

Fórmula: C₆H₅Cl₂NO

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 178.0160

Ref: IN-DA003R41

Isonicotinoyl Chloride Hydrochloride

CAS: 39178-35-3

Fórmula: C₆H₄ClNO·HCl

Pureza: >95.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 178.01

Ref: 3B-I0144

Isonicotinoyl chloride hydrochloride

CAS: 39178-35-3

Isonicotinoyl chloride hydrochloride

Fórmula: C₆H₄ClNO·ClH

Pureza: 95%

Cor e Forma: white powder

Peso molecular: 178.02g/mol

Ref: 54-OR23065

Isonicotinoyl chloride hydrochloride

CAS: 39178-35-3

Isonicotinoyl chloride HCl is a macrocyclic inhibitor of the nuclear hormone receptor (NR) that belongs to the class of organic compounds. It is used in the treatment of inflammatory diseases and infectious diseases. Isonicotinoyl chloride HCl has been shown to inhibit nitric oxide synthase, which leads to an inhibition of inflammatory reactions in various tissues. This compound also inhibits p. aeruginosa and alkylthio group, which may be due to its coordination geometry or aromatic hydrocarbon. Isonicotinoyl chloride HCl binds to mineralocorticoid receptors on cells and blocks their transcriptional activity, thereby inhibiting inflammation and oxidative stress.

Fórmula: C₆H₄ClNO•HCl

Pureza: Min. 95%

Cor e Forma: White To Beige Solid

Peso molecular: 178.02 g/mol

Ref: 3D-FI29482

Isonicotinoyl chloride hydrochloride

CAS: 39178-35-3

Fórmula: C₆H₅Cl₂NO

Pureza: 95%

Cor e Forma: Solid, White to almost white powder

Peso molecular: 178.01

Ref: 10-F066672

Isonicotinyl Chloride Hydrochloride

Produto Controlado

CAS: 39178-35-3

Stability Sensitive to moisture
Applications Isonicotinyl Chloride Hydrochloride, is a heterocyclic building block used for the synthesis of various pharmaceutical and biologically active compounds. It can be used for the preparation of Tetrahydropyrroloquinolinone type dual inhibitors of Aromatase/Aldosterone Synthase, as a novel stagey for breast cancer patients with the risk of cardiovascular diseases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, L., et al.: J. Med. Chem., 56 (2), 460 (2013);

Fórmula: C₆H₅Cl₂NO

Cor e Forma: Neat

Peso molecular: 178.02

Ref: TR-I821755