CAS 3922-61-0

1,1'-[(1R)-1-(3-Hidroxi-7-metil-3-óxido-2,4-dioxa-7-aza-3-fosfaoct-1-il)-1,2-etano diil] dihexadecanoato

Descrição:

1,1'-[(1R)-1-(3-Hidroxi-7-metil-3-óxido-2,4-dioxa-7-aza-3-fosfaoct-1-il)-1,2-etano diil] dihexadecanoato, com número CAS 3922-61-0, é um composto orgânico complexo caracterizado por suas características estruturais únicas, incluindo um grupo fosfonato e grupos de ácidos graxos de cadeia longa. Esta substância provavelmente exibirá propriedades anfifílicas devido à presença de componentes tanto hidrofílicos (os grupos fosfonato e hidroxila) quanto hidrofóbicos (as cadeias de hexadecanoato), o que pode facilitar interações com membranas biológicas e outros ambientes lipídicos. Suas aplicações potenciais podem incluir uso como surfactante, emulsificante ou em sistemas de liberação de medicamentos, particularmente em formulações direcionadas a uma captação celular específica. A presença do grupo fosfonato sugere que também pode ter relevância biológica, possivelmente influenciando a sinalização celular ou vias metabólicas. Além disso, a estereoquímica indicada pela configuração (1R) pode afetar sua atividade biológica e interações com outras moléculas. No geral, este composto representa uma classe de substâncias semelhantes a fosfolípidos com potencial utilidade em várias aplicações bioquímicas e farmacêuticas.

Fórmula: C₃₉H₇₈NO₈P

InChI: InChI=1S/C39H78NO8P/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-38(41)45-35-37(36-47-49(43,44)46-34-33-40(3)4)48-39(42)32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h37H,5-36H2,1-4H3,(H,43,44)/t37-/m1/s1

Chave InChI: InChIKey=SKWDCOTXHWCSGS-DIPNUNPCSA-N

SMILES: [C@@H](OC(CCCCCCCCCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN(C)C)(=O)O

Sinónimos:

• (2R)-3-(((2-(Dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate
• 1,1′-[(1R)-1-(3-Hydroxy-7-methyl-3-oxido-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl] dihexadecanoate
• 1,2-Dihexadecanoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine
• 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine
• <span class="text-smallcaps">L</span>-α-Dipalmitoyl-N,N-dimethylphosphatidylethanolamine
• <span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidyl-N,N-dimethylethanolamine
• Hexadecanoic acid, (1R)-1-(3-hydroxy-7-methyl-3-oxido-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl ester
• Hexadecanoic acid, 1,1′-[(1R)-1-(3-hydroxy-7-methyl-3-oxido-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl] ester
• Hexadecanoic acid, 1-(3-hydroxy-7-methyl-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl ester, P-oxide, (R)-
• Hexadecanoic acid, 1-(3-hydroxy-7-methyl-3-oxido-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl ester, (R)-
• Palmitin, 1,2-di-, 2-(dimethylamino)ethyl hydrogen phosphate, <span class="text-smallcaps">L</span>-
• alpha-Dimethyl dipalmitoylphosphatidylethanolamine
• (R)-1-(3-Hydroxy-7-methyl-2,4-dioxa-7-aza-3-phosphaoct-1-yl)ethylene dipalmitate P-oxide

(2R)-3-(((2-(Dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

CAS: 3922-61-0

(2R)-3-(((2-(Dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Pureza: 98%

Peso molecular: 720.03g/mol

Ref: 54-OR1060696

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine

CAS: 3922-61-0

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine is a liquid crystalline molecule that is used in the synthesis of lipids. It has two hydrophilic heads and one hydrophobic tail, which allows it to be soluble in water. 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine can form bilayers with other molecules due to its transition properties. The transition occurs at temperatures between 43°C and 45°C. This transition is linearly dependent on the temperature increase. When heated to 50°C, this molecule undergoes a second phase transition from a liquid crystalline state to a thermotropic liquid crystalline state. The calorimetry data for this molecule shows that there are no enthalpic or entropic contributions to the entropy change during the phase

Fórmula: C₃₉H₇₈NO₈P

Pureza: Min. 95%

Peso molecular: 720.03 g/mol

Ref: 3D-FD172100

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine

CAS: 3922-61-0

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine is a reagent that is used in research and development as a building block for chemical synthesis. It is a versatile intermediate that can be used to produce other compounds or scaffolds. This compound has been found to be useful in the production of pharmaceuticals, pesticides, and food additives. It can also be used as a reaction component in the preparation of many fine chemicals. 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has CAS number 392261–0 and can be purchased from Sigma Aldrich Chemical Co., Inc.

Fórmula: C₃₉H₇₈NO₈P

Peso molecular: 720.03 g/mol

Ref: 3D-D-6057

1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE

CAS: 3922-61-0

1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity.

Fórmula: C₃₉H₇₈NO₈P

Cor e Forma: Solid

Peso molecular: 720.026

Ref: TM-T85251