CAS 392711-19-2

Rapamycin-d3 (Sirolimus-d3)

CAS: 392711-19-2

Fórmula: C₅₁H₇₆D₃NO₁₃

Cor e Forma: White To Off-White Solid

Peso molecular: 917.21

Ref: 4Z-R-181

Rapamycin-d3

CAS: 392711-19-2

Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).

Fórmula: C₅₁H₇₉NO₁₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 917.19

Ref: TM-T12691

Rapamycin-d3 (contains d0) Technical Grade

Produto Controlado

CAS: 392711-19-2

Stability Moisture Sensitive
Applications Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic.This compound contains aproximately 2% d0.
References Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),

Fórmula: C₅₁₂H₃H₇₆NO₁₃

Cor e Forma: White

Peso molecular: 917.19

Ref: TR-R124002

Rapamycin-d3

CAS: 392711-19-2

Rapamycin-d3 is a drug used to suppress the immune system. It is an immunosuppressant that binds to proteins in the cell and prevents them from functioning. Rapamycin-d3 has been shown to be effective in preventing rejection of transplanted organs as well as treating autoimmune disorders, such as inflammatory bowel disease (IBD). The analysis of this compound can be done using LC-MS/MS methods. In order to optimize the assay, it was necessary to perform a series of validation studies. This included determining crossreactivity with other drugs, developing a method for patient samples, and determining if there was any correlation between treatment response and patient age or sex.

Fórmula: C₅₁H₇₉NO₁₃

Pureza: Min. 95%

Peso molecular: 917.2 g/mol

Ref: 3D-SQA71119

Rapamycin-d3 (contains d0) Technical Grade

CAS: 392711-19-2

Fórmula: C₅₁H₇₆D₃NO₁₃

Pureza: ≥98% deuterated forms (d1-d3)，1mg/ml in ethanol

Cor e Forma: Solid

Peso molecular: 917.1903

Ref: IN-DA00C811