CAS 40077-57-4

Aviptadil

Descrição:

Aviptadil, com o número CAS 40077-57-4, é um peptídeo sintético que é conhecido principalmente por seu papel como análogo do peptídeo intestinal vasoativo (VIP). Ele exibe uma variedade de atividades biológicas, incluindo vasodilatação, modulação de respostas imunológicas e neuroproteção. Aviptadil é composto por 28 aminoácidos e é caracterizado por sua capacidade de se ligar aos receptores de VIP, que estão envolvidos em vários processos fisiológicos, incluindo relaxamento do músculo liso e inibição de respostas inflamatórias. Este peptídeo tem atraído atenção por suas potenciais aplicações terapêuticas, particularmente em condições respiratórias, pois pode ajudar a reduzir a inflamação e melhorar a função pulmonar. Além disso, Aviptadil tem sido investigado para uso potencial no tratamento de condições como disfunção erétil e doenças pulmonares. Sua estabilidade e bioatividade fazem dele um assunto de interesse na pesquisa farmacológica, embora mais estudos sejam necessários para elucidar completamente seus mecanismos de ação e eficácia terapêutica.

Fórmula: C₁₄₇H₂₃₇N₄₃O₄₃S

InChI: InChI=1/C147H237N43O43S/c1-18-75(12)115(142(229)180-96(56-72(6)7)131(218)183-104(145(232)233)63-110(155)200)188-139(226)106(68-192)185-134(221)101(62-109(154)199)177-130(217)95(55-71(4)5)174-132(219)97(58-81-37-41-84(195)42-38-81)175-125(212)88(33-23-26-49-149)167-123(210)89(34-24-27-50-150)171-140(227)113(73(8)9)186-118(205)76(13)164-121(208)93(47-53-234-17)170-127(214)92(45-46-107(152)197)169-122(209)87(32-22-25-48-148)166-124(211)90(35-28-51-161-146(156)157)168-129(216)94(54-70(2)3)173-126(213)91(36-29-52-162-147(158)159)172-143(230)116(78(15)193)189-136(223)98(59-82-39-43-85(196)44-40-82)176-133(220)100(61-108(153)198)178-135(222)103(65-112(203)204)182-144(231)117(79(16)194)190-137(224)99(57-80-30-20-19-21-31-80)181-141(228)114(74(10)11)187-119(206)77(14)165-128(215)102(64-111(201)202)179-138(225)105(67-191)184-120(207)86(151)60-83-66-160-69-163-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,191-196H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,197)(H2,153,198)(H2,154,199)(H2,155,200)(H,160,163)(H,164,208)(H,165,215)(H,166,211)(H,167,210)(H,168,216)(H,169,209)(H,170,214)(H,171,227)(H,172,230)(H,173,213)(H,174,219)(H,175,212)(H,176,220)(H,177,217)(H,178,222)(H,179,225)(H,180,229)(H,181,228)(H,182,231)(H,183,218)(H,184,207)(H,185,221)(H,186,205)(H,187,206)(H,188,226)(H,189,223)(H,190,224)(H,201,202)(H,203,204)(H,232,233)(H4,156,157,161)(H4,158,159,162)/t75-,76-,77-,78+,79+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,113-,114-,115-,116-,117-/m0/s1

Sinónimos:

• Aviptadil Acetate
• VIP (human, mouse, rat) acetate salt

VIP (human, mouse, rat)

CAS: 40077-57-4

VIP, a 28-amino acid peptide belonging to the secretin-glucagon-CRF family, is widely distributed in the central and peripheral nervous systems. Acting both as a neurotransmitter and as a hormone, VIP is involved in a wide variety of biological activities, including vaso- and bronchodilation, smooth muscle relaxation, and stimulation of secretion. An injectable formulation of this peptide in combination with the adrenergic drug phentolamine is expected to provide a new and effective alternative for erectile dysfunction patients.

Fórmula: C₁₄₇H₂₃₈N₄₄O₄₂S

Pureza: ≥ 99%

Cor e Forma: White Powder

Peso molecular: 3325.84

Ref: 01-4011611

VIP (human, mouse, rat) acetate salt H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 acetate salt

CAS: 40077-57-4

Fórmula: C₁₄₇H₂₃₈N₄₄O₄₂S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 3325.7972

Ref: IN-DA01EAG5

Aviptadil

CAS: 40077-57-4

Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction.

Fórmula: C₁₄₇H₂₃₈N₄₄O₄₂S

Cor e Forma: Solid

Peso molecular: 3325.8

Ref: TM-TP1016

Aviptadil Acetate

CAS: 40077-57-4

Fórmula: C₁₄₇H₂₃₈N₄₄O₄₂S₁

Pureza: 95%~99%

Cor e Forma: White to Off-white Powder

Peso molecular: 3325.8

Ref: BP-BPPG009

Aviptadil Acetate

CAS: 40077-57-4

Ref: 7W-GX3450

Vasoactive Intestinal peptide

CAS: 40077-57-4

Peptide Vasoactive Intestinal peptide is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Fórmula: C₁₄₇H₂₃₈N₄₄O₄₂S

Peso molecular: 3,325.7 g/mol

Ref: 3D-PP44484

VIP (Human, Porcine)

CAS: 40077-57-4

VIP is a peptide that is an activator of cAMP-dependent protein kinase (PKA) and phospholipase C. It also inhibits the release of histamine from mast cells, stimulates gastric acid secretion, and causes vasodilation. VIP has been shown to interact with a number of proteins including ion channels and receptors. The peptide is a ligand for the neuropeptide Y receptor (NPY-R) and is involved in the regulation of appetite, immune responses, and blood pressure. VIP can be used as a research tool for studying protein interactions or as an inhibitor in pharmacological studies.

Fórmula: C₁₄₇H₂₃₈N₄₄O₄₂S

Pureza: Min. 95%

Peso molecular: 3,325.8 g/mol

Ref: 3D-PVA-4110-S

VIP (Human, Porcine)

CAS: 40077-57-4

VIP is a polypeptide that belongs to the vasoactive intestinal peptide family. VIP is a potent stimulator of adenylate cyclase, which increases intracellular cAMP levels and activates protein kinase A. VIP has been shown to interact with ion channel receptors, such as the nicotinic acetylcholine receptor, and regulate membrane potentials in neuronal cells. It also functions as a ligand for G protein-coupled receptors and can be used as an immunogen or antibody against VIP. VIP has been shown to have a variety of pharmacological effects including the ability to stimulate cell proliferation and inhibit apoptosis. VIP has also been shown to function as an activator of latent TGF-β1, which may play a role in tumor suppression.

Fórmula: C₁₄₇H₂₃₈N₄₄O₄₂S

Pureza: Min. 95%

Peso molecular: 3,325.8 g/mol

Ref: 3D-PVA-4110-V

Vasoactive Intestinal peptide

CAS: 40077-57-4

Custom research peptide; min purity 95%.

Fórmula: C₁₄₇H₂₃₈N₄₄O₄₂S

Pureza: Min. 95%

Peso molecular: 3,325.7 g/mol

Ref: 3D-PV17118