CAS 4009-98-7

Cloreto de (metoximetil)trifenilfosfônio

Descrição:

Cloreto de (metoximetil)trifenilfosfônio, com o número CAS 4009-98-7, é um sal de amônio quaternário caracterizado por seu cátion triphenylphosphonium e um grupo metoximetil. Este composto geralmente aparece como um sólido branco a off-white e é solúvel em solventes orgânicos polares. É conhecido por seu papel na síntese orgânica, particularmente na formação de ylidos de fosfonio, que são intermediários úteis em várias reações, incluindo a reação de Wittig para a síntese de alcenos. A presença do grupo metoximetil aumenta suas propriedades de reatividade e solubilidade. Além disso, a parte triphenylphosphonium contribui para sua estabilidade e capacidade de atuar como nucleófilo. Este composto é frequentemente manuseado com cuidado devido à sua potencial toxicidade e deve ser armazenado em um local fresco e seco, longe de materiais incompatíveis. No geral, Cloreto de (metoximetil)trifenilfosfônio é um reagente valioso na química orgânica sintética, facilitando a formação de estruturas moleculares complexas.

Fórmula: C₂₀H₂₀OP·Cl

InChI: InChI=1S/C20H20OP.ClH/c1-21-17-22(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20;/h2-16H,17H2,1H3;1H/q+1;/p-1

Chave InChI: InChIKey=SJFNDMHZXCUXSA-UHFFFAOYSA-M

SMILES: [P+](COC)(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Cl-]

Sinónimos:

• (Methoxymethyl)triphenylphosphanium chloride
• Aurora Ka-1153
• Chloro(methoxy)triphenylphosphorane
• Chloro-Methoxy-Triphenyl-Phosphorane
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• MMC
• Methoxymethyl Triphenyl Phosphonium Chloride
• Methoxymethyltriphenyl Phosphoniumchloride
• NSC 49223
• Phosphonium, (methoxymethyl)triphenyl-, chloride
• Phosphonium, (methoxymethyl)triphenyl-, chloride (1:1)
• Phosphorane, Chloromethoxytriphenyl-
• Triphenyl(methoxymethyl)phosphonium chloride
• [(Methyloxy)methyl]triphenylphosphonium chloride
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• (Methoxymethyl)triphenylphosphonium chloride
• Methoxymethyltriphenylphosphanium chloride
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-

(Methoxymethyl)triphenylphosphonium Chloride

CAS: 4009-98-7

Fórmula: C₂₀H₂₀ClOP

Pureza: >99.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 342.80

Ref: 3B-M0828

(Methoxymethyl)triphenylphosphonium chloride

CAS: 4009-98-7

Fórmula: C₂₀H₂₀ClOP

Pureza: 98%

Cor e Forma: Solid, Crystalline

Peso molecular: 342.8

Ref: 10-F092547

(Methoxymethyl)triphenylphosphonium chloride, 98+%

CAS: 4009-98-7

(Methoxymethyl)triphenylphosphonium chloride is used as a phase transfer catalyst and in the synthesis of taxol-A fragment. It is widely used in the synthesis of pharmaceutical product cephalotaxine, which is used as an antiviral and antitumor agent. This Thermo Scientific Chemicals brand product

Fórmula: C₂₀H₂₀ClOP

Pureza: 98+%

Cor e Forma: White to very pale cream, Powder or crystals or crystalline powder

Peso molecular: 342.80

Ref: 02-A14380

(Methoxymethyl)Triphenylphosphonium Chloride

CAS: 4009-98-7

Fórmula: C₂₀H₂₀ClOP

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 342.7990

Ref: IN-DA0032DE

(Methoxymethyl)tris(phenyl)phosphonium chloride

CAS: 4009-98-7

(Methoxymethyl)tris(phenyl)phosphonium chloride

Fórmula: C₂₀H₂₀OP·Cl

Pureza: 98%

Cor e Forma: white crystalline solid

Peso molecular: 342.80g/mol

Ref: 54-OR10664

Methoxymethyl triphenylphosphonium chloride

CAS: 4009-98-7

Fórmula: C₂₀H₂₀ClOP

Cor e Forma: White to off-white crystalline powder

Peso molecular: 342.81

Ref: 7W-GK7979

[(Methoxy)methyl]triphenylphosphonium Chloride

CAS: 4009-98-7

Applications [(Methoxy)methyl]triphenylphosphonium Chloride is used in the synthesis of Cephalotaxine (C261050), an antiviral and antitumor agent. Also used in the synthesis of Taxol A fragment.
References Sells, M., et al.: J. Virol., 62, 2836 (1988), Kaneko, S., et al.: J. Clin. Microbiol., 27, 1930 (1989), Baba, Y., et al.: Bioorg. Med. Chem., 13, 5164 (2005), Romero, M., et al.: Antiviral Res., 68, 75 (2005); Hirai, S. et al.: Tetrahedron Lett., 54, 1888 (2013); Xing, P. et al.: Synth., 45, 596 (2013);

Fórmula: C₂₀H₂₀OP·Cl

Cor e Forma: Neat

Peso molecular: 342.80

Ref: TR-M264680

(Methoxymethyl) triphenylphosphonium chloride

CAS: 4009-98-7

Methoxymethyl triphenylphosphonium chloride (MMTPC) is a chemical compound that has been used in vitro as an inhibitor of microbial growth. MMTPC has been shown to be effective against a number of bacterial strains, including methicillin-resistant Staphylococcus aureus and Mycobacterium tuberculosis. This agent inhibits the synthesis of proteins and nucleic acids, which may lead to cell death by inhibiting protein synthesis or by preventing DNA synthesis. MMTPC has been shown to be effective for the treatment of congestive heart failure, coronary heart disease, and autoimmune diseases. It also binds to receptors on cells that are involved in the inflammatory response, such as cytokines and leukocytes.

Fórmula: C₂₀H₂₀ClOP

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 342.8 g/mol

Ref: 3D-FM34383