CAS 402-49-3

4-(Trifluorometil)brometo de benzilo

Descrição:

4-(Trifluorometil)brometo de benzilo é um composto orgânico caracterizado pela presença de um grupo bromobenzila com um substituinte trifluorometila na posição para. Sua fórmula molecular é C9H7BrF3, indicando a presença de átomos de carbono, hidrogênio, bromo e flúor. Este composto geralmente aparece como um líquido incolor a amarelo pálido e é conhecido por sua reatividade devido à presença do átomo de bromo, que pode participar de reações de substituição nucleofílica. O grupo trifluorometila contribui para as propriedades eletrônicas únicas do composto, aumentando sua lipofilicidade e potencialmente influenciando sua atividade biológica. 4-(Trifluorometil)brometo de benzilo é frequentemente utilizado na síntese orgânica, particularmente na preparação de produtos farmacêuticos e agroquímicos, devido à sua capacidade de servir como um reagente eletrofílico. Precauções de segurança devem ser tomadas ao manusear este composto, pois pode representar riscos à saúde por inalação ou contato com a pele. Métodos adequados de armazenamento e descarte são essenciais para mitigar o impacto ambiental e garantir a segurança em ambientes de laboratório.

Fórmula: C₈H₆BrF₃

InChI: InChI=1S/C8H6BrF3/c9-5-6-1-3-7(4-2-6)8(10,11)12/h1-4H,5H2

Chave InChI: InChIKey=IKSNDOVDVVPSMA-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC=C(CBr)C=C1

Sinónimos:

• 1-Trifluoromethyl-4-(bromomethyl)benzene
• 4-(Trifluoromethyl)Benzyl Bromide
• 4-Bromomethylbenzotrifluoride
• 4-Trifluoromethylbenzyl Bromide
• Benzene, 1-(bromomethyl)-4-(trifluoromethyl)-
• p-(Trifluoromethyl)benzyl bromide
• p-Xylene, α′-bromo-α,α,α-trifluoro-
• α′-Bromo-α,α,α-trifluoro-p-xylene
• 1-(Bromomethyl)-4-(trifluoromethyl)benzene

4-(Trifluoromethyl)benzyl Bromide

CAS: 402-49-3

Fórmula: C₈H₆BrF₃

Pureza: >98.0%(GC)

Cor e Forma: White or Colorless to Light yellow powder to lump to clear liquid

Peso molecular: 239.04

Ref: 3B-T1313

4-(Trifluoromethyl)benzyl bromide, 98%

CAS: 402-49-3

4-(Trifluoromethyl)benzyl bromide can be used to produce p-trifluoromethylbenzyl phenyl sulfide. It is used in medicine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The

Fórmula: C₈H₆BrF₃

Pureza: 98%

Cor e Forma: Crystals or powder or crystalline powder or fused solid, White to cream

Peso molecular: 239.04

Ref: 02-A16895

4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

Fórmula: C₈H₆BrF₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 239.0324

Ref: IN-DA0033U8

4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

4-(Trifluoromethyl)benzyl bromide

Fórmula: C₈H₆BrF₃

Pureza: 98%

Cor e Forma: white to off white fused solid

Peso molecular: 239.03g/mol

Ref: 54-PC7633

4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

Fórmula: C₈H₆BrF₃

Pureza: 98.0%

Cor e Forma: Low Melting Solid

Peso molecular: 239.035

Ref: 10-F007607

4-(Trifluoromethyl)benzyl Bromide

Produto Controlado

CAS: 402-49-3

Applications 4-(Trifluoromethyl)benzyl Bromide is a useful building block. It is used in the synthesis of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles with antiviral activities.It is also used to prepare 2-[(4-diarylmethoxy)phenyl]benzimidazoles as potent inhibitors of hepatitis C virus NS5B polymerase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Porcari, A., et al.: J. Med. Chem., 41, 1252 (1998); Ishida, T., et al.: Bioorg. Med. Chem. Lett., 16, 1859 (2006)

Fórmula: C₈H₆BrF₃

Cor e Forma: Neat

Peso molecular: 239.03

Ref: TR-T790585

4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond.

Fórmula: C₈H₆BrF₃

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 239.03 g/mol

Ref: 3D-FT34370