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CAS 41078-70-0
:3-(2-cloroetil)-2-metil-4H-pirido[1,2-a]pirimidin-4-ona
Descrição:
3-(2-cloroetil)-2-metil-4H-pirido[1,2-a]pirimidin-4-ona, com o número CAS 41078-70-0, é um composto orgânico heterocíclico caracterizado por sua estrutura de pirido-pirimidina. Este composto apresenta um grupo cloroetila, que contribui à sua reatividade e potencial atividade biológica. A presença do grupo metila aumenta sua lipofilicidade, podendo influenciar suas propriedades farmacocinéticas. Tipicamente, compostos dessa classe podem exibir várias atividades biológicas, incluindo propriedades antimicrobianas ou anticancerígenas, devido à sua capacidade de interagir com alvos biológicos, como enzimas ou receptores. A estrutura molecular sugere que pode participar de ligações de hidrogênio e outras interações, que são cruciais para sua função biológica. Além disso, a estabilidade e solubilidade do composto podem variar com base nas condições ambientais, como pH e polaridade do solvente. No geral, 3-(2-cloroetil)-2-metil-4H-pirido[1,2-a]pirimidin-4-ona representa uma classe de compostos que podem ter implicações significativas na química medicinal e no desenvolvimento de medicamentos.
Fórmula:C11H11ClN2O
InChI:InChI=1S/C11H11ClN2O/c1-8-9(5-6-12)11(15)14-7-3-2-4-10(14)13-8/h2-4,7H,5-6H2,1H3
Chave InChI:InChIKey=LFTGLYCNMGGMKL-UHFFFAOYSA-N
SMILES:O=C1N2C(=NC(C)=C1CCCl)C=CC=C2
Sinónimos:- 3-(2-Chloroethyl)-2-Methylpyrido[1,2-A]Pyrimidin-4-One
- 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-2-methyl-
- 3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- :3-(2-chloroethyl)-2-methyl-4h-pyrido-[1,2-a]pyrimidin-4-one
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9 produtos.
3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Fórmula:C11H11ClN2OPureza:98%Cor e Forma:SolidPeso molecular:222.67083-(2-Chloroethyl)-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One
CAS:3-(2-Chloroethyl)-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-OnePureza:98%Peso molecular:222.67g/molRisperidone Impurity 3
CAS:Fórmula:C11H11ClN2OCor e Forma:White To Off-White SolidPeso molecular:222.673-(2-Chloro-ethyl)-2-methyl-pyrido[1,2-a]pyrimidin-4-one
CAS:Fórmula:C11H11ClN2OPureza:98%Cor e Forma:SolidPeso molecular:222.673-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>Applications An intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, T., et al.: J. Med. Chem., 33, 527 (1990), Yapi, A., et al.: Chem. Pharm. Bull., 48, 1886 (2000), Yapi, A., et al.: Arch. Pharm., 339, 201 (2006); Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988); Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990); Green, B.: Curr. Med. Res. Opin., 16, 57 (2000);<br></p>Fórmula:C11H11ClN2OCor e Forma:NeatPeso molecular:222.673-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a chemical compound that is used to synthesize the drug paliperidone. The reaction time of this synthesis reaction is high and the yield is high. The conformation of the product can be predicted with theory. The hydrochloride salt of the product has a higher solubility in water than does the free base form. The reactants are 3-(2-chloroethyl) pyridine and 2-methyl 4H pyrido[1,2-a]pyrimidin-4-one, which are both cheap and easily accessible. This synthesis can be carried out using solvents such as phosphorus oxychloride or carbonyl oxychloride. The dihedral angle for this molecule is around 100 degrees, which makes it a planar molecule. This compound reacts with pyridine</p>Fórmula:C11H11ClN2OPureza:Min. 95%Peso molecular:222.67 g/mol3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Fórmula:C11H11ClN2OPureza:>98.0%(GC)(T)Cor e Forma:White to Light yellow powder to crystalPeso molecular:222.67
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0073CI.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR1010637.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0491.29-0025.jpg&w=3840&q=75)
![3-(2-Chloro-ethyl)-2-methyl-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF036503.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FC366150.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FFC20228.jpg&w=3840&q=75)
![3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FC2716.jpg&w=3840&q=75)
