CAS 43188-86-9

hidrocortisona 3-O-carboximetiloxima

Descrição:

hidrocortisona 3-O-carboximetiloxima, com o número CAS 43188-86-9, é um derivado da hidrocortisona, um hormônio esteroide produzido pelas glândulas adrenais. Este composto apresenta um grupo funcional carboximetiloxima na posição 3 da estrutura da hidrocortisona, o que modifica suas propriedades químicas e atividade biológica. É tipicamente caracterizado por sua fórmula molecular, que reflete a presença de átomos de carbono, hidrogênio, nitrogênio e oxigênio. A introdução do grupo oxima pode influenciar a solubilidade, estabilidade e reatividade do composto, potencialmente melhorando seus efeitos farmacológicos. Os derivados da hidrocortisona são frequentemente estudados por suas propriedades anti-inflamatórias e imunossupressoras, tornando-os relevantes em aplicações terapêuticas. As características específicas, como ponto de fusão, solubilidade e dados espectrais, dependeriam da pureza do composto e das condições sob as quais é analisado. No geral, hidrocortisona 3-O-carboximetiloxima representa uma modificação de um esteroide bem conhecido, com possíveis implicações em química medicinal e farmacologia.

Fórmula: C₂₃H₃₃NO₇

InChI: InChI=1/C23H33NO7/c1-21-7-5-14(24-31-12-19(28)29)9-13(21)3-4-15-16-6-8-23(30,18(27)11-25)22(16,2)10-17(26)20(15)21/h9,15-17,20,25-26,30H,3-8,10-12H2,1-2H3,(H,28,29)/b24-14+/t15-,16-,17-,20?,21-,22-,23-/m0/s1

Sinónimos:

• 4-PREGNEN-11-BETA, 17,21-TRIOL-3,20-DIONE 3-O-CARBOXYMETHYLOXIME
• HYDROCORTISONE 3-(O-CARBOXYMETHYL)OXIME
• CORTISOL 3-CMO
• 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 3-[O-CARBOXYMETHYL]OXIME
• Cortisol 3-Carboxymethyloxime
• 4-Pregnene-11β,17α,21-Triol-3,20-Dione 3-(O-Carboxymethyl)Oxime
• 11β,17α,21-trihydroxy-4-pregnene-3,20-dione 3-(o-carboxymethyl)oxime
• 11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 3-[O-CARBOXYMETHYL]OXIME
• Hydrocortisone Impurity 56
• Acetic acid, 2-[[[(11β)-11,17,21-trihydroxy-20-oxopregn-4-en-3-ylidene]amino]oxy]-
• Cortisol 3-(O-carboxymethyl)oxime, 4-Pregnene-11β,17α,21-triol-3,20-dione 3-(O-carboxymethyl)oxime, 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 3-(O-carboxymethyl)oxime
• CORTISOL 3-[O-CARBOXYMETHYL]OXIME
• HYDROCORTISONE 3-CMO
• Hydrocortisone 3-(O-Carboxymethyl)oxime (E/Z Mixture)
• 4-PREGNEN-11β, 17, 21-TRIOL-3, 20-DIONE 3-O-CARBOXYMETHYLOXIME

Hydrocortisone 3-(O-carboxymethyl)oxime

CAS: 43188-86-9

Fórmula: C₂₃H₃₃NO₇

Peso molecular: 435.51

Ref: 7W-GL3591

Hydrocortisone 3-(O-carboxymethyl)oxime

Produto Controlado

CAS: 43188-86-9

Hydrocortisone 3-(O-carboxymethyl)oxime is a water-soluble compound that has shown potential in the treatment of lung cancer. It has been found to enhance the uptake of d-allulose, a sugar substitute, which can help regulate blood sugar levels. Additionally, hydrocortisone 3-(O-carboxymethyl)oxime has been incorporated into nanocomposites for photocatalytic applications, specifically in the degradation of cancer-causing substances in water. This compound has also demonstrated controlled release properties when used as an electrode coating, allowing for targeted delivery of therapeutic agents. In studies conducted on human cells, hydrocortisone 3-(O-carboxymethyl)oxime showed promising results in inhibiting the growth of lung cancer cells and reducing tumor size. Further research is underway to explore its potential as a novel anticancer therapy.

Fórmula: C₂₃H₃₃NO₇

Peso molecular: 435.52 g/mol

Ref: 3D-J-022769

Cortisol 3-CMO

CAS: 43188-86-9

Cortisol 3-CMO is a highly effective antibody-drug conjugate that targets choroidal neovascularization, a condition characterized by the abnormal growth of blood vessels in the choroid layer of the eye. It works by binding to specific growth factors involved in this process and delivering a cytotoxic toxin subunit to the targeted cells. This leads to the lysis and elimination of these cells, effectively treating the condition. The unique feature of Cortisol 3-CMO is its fluorophore component, which allows for easy visualization and tracking of the drug within the body. This enables healthcare professionals to monitor its distribution and efficacy during treatment. In addition to its therapeutic benefits, Cortisol 3-CMO also exhibits excellent photostability, ensuring its potency even under prolonged exposure to light. This makes it a reliable and long-lasting solution for patients suffering from choroidal neovascularization. Developed using advanced monoclonal antibody technology, Cortisol 3-CMO offers high specificity and

Fórmula: C₂₃H₃₃NO₇

Pureza: Min. 95%

Peso molecular: 435.51 g/mol

Ref: 3D-80-IC15

Hydrocortisone 3-(O-carboxymethyl)oxime

Produto Controlado

CAS: 43188-86-9

Hydrocortisone 3-(O-carboxymethyl)oxime is a fine chemical that is used as a building block in research and speciality chemicals. It has been shown to be a useful intermediate for the synthesis of other compounds, such as corticosteroids, and could be used as a scaffold for the synthesis of natural products. Hydrocortisone 3-(O-carboxymethyl)oxime is an ester that is derived from hydrocortisone by reacting it with oxalyl chloride and methanol. This product has CAS No. 43188-86-9, indicating that it is a high quality product.

Fórmula: C₂₃H₃₃NO₇

Pureza: Min. 95%

Peso molecular: 435.5 g/mol

Ref: 3D-FH181853

Hydrocortisone 3-(O-Carboxymethyl)oxime (E/Z Mixture)

Produto Controlado

CAS: 43188-86-9

Applications Hydrocortisone 3-(O-Carboxymethyl)oxime is a model steroid that was coupled with bovine serum albumin (F-3-O-CMO-BSA) and used as immunogen to raise the antiserum in New Zealand white rabbits.It is derived from Hydrocortisone (H714615), which is a topical corticosteroid (1), more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis (3); suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References Nara, S., et al.: Anal. Biochem., 373, 18-25 (2008)

Fórmula: C₂₃H₃₃NO₇

Cor e Forma: Neat

Peso molecular: 435.511

Ref: TR-H716568