CAS 434-16-2

7-Desidrocolesterol

Descrição:

7-Desidrocolesterol, com o número CAS 434-16-2, é um esterol e um precursor na biossíntese do colesterol. É caracterizado pela sua fórmula molecular C27H44O e apresenta uma estrutura que inclui um núcleo esteroide com uma dupla ligação na posição do sétimo carbono. Este composto é um sólido cristalino incolor que é insolúvel em água, mas solúvel em solventes orgânicos. 7-Desidrocolesterol desempenha um papel crucial no corpo humano, particularmente na pele, onde pode ser convertido em vitamina D3 quando exposto à luz ultravioleta. Esta conversão é vital para o metabolismo do cálcio e a saúde óssea. Além disso, 7-Desidrocolesterol é utilizado em várias aplicações bioquímicas e farmacêuticas, incluindo pesquisas sobre o metabolismo do colesterol e a síntese de hormonas esteroides. Suas propriedades únicas e importância biológica fazem dele um composto importante tanto na bioquímica quanto na medicina.

Fórmula: C₂₇H₄₄O

InChI: InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1

Chave InChI: InChIKey=UCTLRSWJYQTBFZ-DDPQNLDTSA-N

SMILES: C[C@@]12[C@](C=3[C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]

Sinónimos:

• (3Beta)-Cholesta-5,7-Dien-3-Ol
• (3β)-Cholesta-5,7-dien-3-ol
• 5,7-Cholestandien-3β-ol
• 7,8-Didehidrocolesterol
• 7,8-Didehydrocholesterol
• 7-Dehydrocholesterin
• Cholesta-5,7-Dien-3-Beta-Ol
• Cholesta-5,7-Dien-3-Ol
• Cholesta-5,7-dien-3-ol, (3β)-
• Cholesta-5,7-dien-3β-ol
• Cholesterol, 7-dehydro-
• Dehydrocholesterol
• Nsc 18159
• Provitamin D3
• Provitamin D₃
• Provitamine
• Δ5,7-Cholestadien-3β-ol
• Δ7-Cholesterol
• Δ^5,7-Cholestadien-3β-ol
• Δ⁷-Cholesterol

7-Dehydrocholesterol ((3S,9S,10R,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol)

CAS: 434-16-2

Provitamins

Fórmula: C₂₇H₄₄O

Cor e Forma: Off-White Solid

Peso molecular: 384.33922

Ref: 45-1A02070

(3β)-Cholesta-5,7-dien-3-ol

CAS: 434-16-2

Fórmula: C₂₇H₄₄O

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 384.6377

Ref: IN-DA0037HD

7-Dehydrocholesterol

CAS: 434-16-2

7-Dehydrocholesterol

Pureza: ≥98%

Peso molecular: 384.64g/mol

Ref: 54-BUP14706

7-Dehydrocholesterol

CAS: 434-16-2

Fórmula: C₂₇H₄₄O

Pureza: ≥ 95.0% (dried basis)

Cor e Forma: White, off-white or faint yellow powder or crystals

Peso molecular: 384.64

Ref: 7W-GL8522

Cholecalciferol EP Impurity B (3-β-7-Dehydro Cholesterol)

CAS: 434-16-2

Fórmula: C₂₇H₄₄O

Peso molecular: 384.65

Ref: 4Z-C-5121

7-Dehydrocholesterol

CAS: 434-16-2

7-Dehydrocholesterol

Pureza: 95%

Peso molecular: 384.64g/mol

Ref: 54-OR1012072

7-Dehydrocholesterol

CAS: 434-16-2

Fórmula: C27H44O

Pureza: >90%

Cor e Forma: Solid

Peso molecular: 384.64

Ref: 48-60-1471

Cholesta-5,7-dien-3β-ol (7,8-Didehydrocholesterol; Provitamin D3)

Produto Controlado

CAS: 434-16-2

Fórmula: C₂₇H₄₄O

Cor e Forma: Neat

Peso molecular: 384.64

Ref: 86-MM0249.02

7-Dehydrocholesterol

CAS: 434-16-2

7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.

Fórmula: C₂₇H₄₄O

Pureza: 99.23%

Cor e Forma: Solid

Peso molecular: 384.64

Ref: TM-T4923

(3β)-7-Dehydro Cholesterol

Produto Controlado

CAS: 434-16-2

Fórmula: C₂₇H₄₄O

Cor e Forma: White To Yellow

Peso molecular: 384.64

Ref: TR-D229455

7-Dehydrocholesterol - min 95%

Produto Controlado

CAS: 434-16-2

7-Dehydrocholesterol is a cholesterol precursor that is synthesized in the skin and liver. It is also found in other tissues, including the brain, where it is converted to cholesterol. 7-Dehydrocholesterol can be used as an indicator of sterol metabolism because its concentration reflects the rate of cholesterol production by the body. The kinetics of 7-dehydrocholesterol are similar to those of cholesterol, and it has been used as a marker for measuring cholesterol synthesis rates in humans. Skin cells contain 7-dehydrocholesterol, which may be important for skin cancer prevention. 7-Dehydrocholesterol has also been shown to be effective in reducing autoimmune diseases such as lupus erythematodes and bowel diseases such as Crohn's disease, although further research is needed.

Fórmula: C₂₇H₄₄O

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 384.64 g/mol

Ref: 3D-FD165801

7-Dehydrocholesterol

Produto Controlado

CAS: 434-16-2

7-Dehydrocholesterol is a sterol found in cells. It is the immediate precursor of cholesterol, which is synthesized from 7-dehydrocholesterol by the enzyme 7-dehydrocholesterol reductase. This compound has been shown to be an important regulator of mitochondrial membrane potential and ATP synthesis in neuro2a cells. Furthermore, 7-dehydrocholesterol has been shown to have therapeutic effects on metabolic disorders, skin cancer, and polymerase chain reactions. It also has receptor activity and enzyme activities that are not yet well understood. The untreated group had higher levels of 7-dehydrocholesterol than the treated group.

Fórmula: C₂₇H₄₄O

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 384.64 g/mol

Ref: 3D-FD20900

(3S,9S,10R,13R,14R,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

CAS: 434-16-2

Pureza: 97%

Peso molecular: 384.6480103

Ref: 10-F868697

3-β-7-Dehydro Cholesterol

CAS: 434-16-2

Fórmula: C₂₇H₄₄O

Peso molecular: 384.64

Ref: ST-EA-CP-C71006