CAS 4342-03-4
:Dacarbazina
Descrição:
Dacarbazina, com o número CAS 4342-03-4, é um agente antineoplásico utilizado principalmente na quimioterapia para o tratamento de vários tipos de câncer, incluindo melanoma e linfoma de Hodgkin. É classificado como um agente alquilante, o que significa que atua interferindo no processo de replicação do DNA nas células cancerosas, levando, em última instância, à morte celular. Dacarbazina é um pó cristalino branco a off-white que é solúvel em água e tem um peso molecular relativamente baixo. Sua fórmula química é C6H10N4O2S, e é frequentemente administrado por via intravenosa. O medicamento é conhecido por ter uma variedade de efeitos colaterais, incluindo náuseas, vômitos e mielossupressão, o que exige monitoramento cuidadoso durante o tratamento. Dacarbazina é tipicamente usado em combinação com outros agentes quimioterápicos para aumentar sua eficácia e melhorar os resultados dos pacientes. Como todos os agentes quimioterápicos, seu uso deve ser orientado por um profissional de saúde, considerando o tipo específico de câncer e o estado de saúde do paciente.
Fórmula:C6H10N6O
InChI:InChI=1/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+
Chave InChI:InChIKey=FDKXTQMXEQVLRF-UHFFFAOYSA-N
SMILES:N(=NN(C)C)C1=C(C(N)=O)N=CN1
Sinónimos:- (4E)-4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
- (Dimethyltriazeno)imidazolecarboxamide
- 1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazen-1-yl)-
- 1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-
- 1H-Imidazole-4-carboxamide, 5-[2-(dimethylamino)diazenyl]-
- 4(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide
- 4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
- 4-(Dimethyltriazeno)imidazole-5-carboxamide
- 5(4)-(3,3-Dimethyl-1-triazeno)imidazole-4(5)-carboxamide
- 5(or 4)-(3,3-Dimethyl-1-triazeno)imidazole-4(or 5)carboxamide
- 5-(3,3'-Dimethyl-1-triazeno)imidazole-4-carboxamide
- 5-(3,3-Dimethyl-1-triazen-1-yl)-1H-imidazole-4-carboxamide
- 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide
- 5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide
- 5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide
- 5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
- 5-(Dimethyltriazeno)imidazole-4-carboxamide
- 5-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide
- Biocarbazine R
- DIC
- DTIC-Dome
- Dacarbasine
- Dacarbazin
- Dacarbazino
- Deticene
- Detimedac
- Dtic
- Dtie
- Icdmt
- Icdt
- Imidazole-4(or 5)-carboxamide, 5(or 4)-(3,3-dimethyl-1-triazeno)-
- Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-
- Nci C04717
- Nsc 45388
- TOSLAB 25071
- 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamid
- DACARBAZINE
- 4-(3,3-dimethyltriazeno)imidazole-5-carboxamide
- biocarbaziner
- 5-(3,3-dimethyl-1-triazeno1-imidazole-4-carboxamid
- 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide
- 5-(3,3-dimethyl-1-triazenyl)-1h-imidazole-4-carboxamid
- Ver mais sinónimos
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16 produtos.
Dacarbazine
CAS:Fórmula:C6H10N6OPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:182.19Dacarbazine
CAS:<p>Used in treatment of malignant melanoma and sarcomas. Generates methyl adducts to purine bases in DNA This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesa</p>Fórmula:C6H10N6OPeso molecular:182.18Dacarbazine
CAS:DacarbazineFórmula:C6H10N6OCor e Forma:Off-White. To. Light YellowPeso molecular:182.1832DACARBAZINE CRS
CAS:<p>DACARBAZINE CRS</p>Fórmula:C6H10N6OCor e Forma:Crystalline Powder. White. Yellow. Powder.Peso molecular:182.1832Dacarbazine
CAS:<p>Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi</p>Fórmula:C6H10N6OCor e Forma:Off-White White PowderPeso molecular:182.091615-[(1E)-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide
CAS:Fórmula:C6H10N6OPureza:98%Cor e Forma:SolidPeso molecular:182.1832Dacarbazine
CAS:<p>Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.</p>Fórmula:C6H10N6OPureza:99.78% - 99.87%Cor e Forma:Ivory Microcrystaline Substance Physical Description White To Ivory Microcrystals Or Off-White Crystalline Solid (Ntp 1992)Peso molecular:182.18Dacarbazine
CAS:Fórmula:C6H10N6OPureza:98.0 - 102.0 % (anhydrous substance)Cor e Forma:White to off-white or pale yellow crystalline powderPeso molecular:182.18Dacarbazine
CAS:Produto ControladoFórmula:C6H10N6OCor e Forma:Off-White To Light YellowPeso molecular:182.18Dacarbazine
CAS:<p>Dacarbazine is an antineoplastic agent that inhibits the division of cancer cells by acting as a prodrug to produce the active form, dacarbazine trioxide. It has been shown to be effective in vitro for the treatment of melanoma and other solid tumours. Dacarbazine has been used in combination with other chemotherapeutic agents, such as temozolomide, for the treatment of brain tumours and carcinoid syndrome. The drug is associated with acute toxicities, including myelosuppression, alopecia, nausea and vomiting. These side effects can be reduced using interferon-alfa-2b. Dacarbazine has also been shown to have mitochondrial membrane potential (MMP) stabilizing properties that are independent of its cytotoxic effects on tumour cells.</p>Fórmula:C6H10N6OPureza:Min. 95%Cor e Forma:White PowderPeso molecular:182.18 g/mol4-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide
CAS:Pureza:98%Cor e Forma:SolidPeso molecular:182.1869965
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