CAS 438-59-5

Cloridrato de 10,11-dideidronortriptilina

Descrição:

Cloridrato de 10,11-dideidronortriptilina é um composto químico que pertence à classe dos antidepressivos tricíclicos. É um derivado da nortriptilina, que é conhecida por seu uso no tratamento da depressão e certos tipos de dor. O composto apresenta uma estrutura tricíclica, caracterizada por três anéis interconectados, contribuindo para sua atividade farmacológica. Como sal de cloridrato, é tipicamente mais solúvel em água, facilitando seu uso em formulações farmacêuticas. O composto atua principalmente inibindo a recaptação de neurotransmissores como norepinefrina e serotonina, melhorando assim o humor e aliviando os sintomas depressivos. Suas propriedades químicas incluem um peso molecular específico e um ponto de fusão definido, que são essenciais para sua caracterização e controle de qualidade em aplicações farmacêuticas. Os perfis de segurança e eficácia são críticos, e como outros antidepressivos tricíclicos, pode ter efeitos colaterais, incluindo sedação e efeitos anticolinérgicos. O manuseio e a dosagem adequados são essenciais para minimizar os riscos associados ao seu uso.

Fórmula: C₁₉H₂₀ClN

InChI: InChI=1/C19H19N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-13,20H,6,14H2,1H3;1H

Chave InChI: InChIKey=UZMPCPFDZYTEJG-UHFFFAOYSA-N

SMILES: C(CCNC)=C1C=2C(C=CC=3C1=CC=CC3)=CC=CC2.Cl

Sinónimos:

• 1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-, hydrochloride (9CI)
• 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride
• 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride (1:1)
• 10,11-Didehydronortriptyline hydrochloride
• 10,11-thelda-Nortriptyline hydrochloride
• 3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine hydrochloride (1:1)
• 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, N-methyl-, hydrochloride
• 5H-Dibenzo[a,d]cycloheptene-Δ^5,γ-propylamine, N-methyl-, hydrochloride
• N 7068 hydrochloride
• Norproheptatriene hydrochloride
• Ro 4-6011
• 3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)propyl(methyl)ammonium chloride
• 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, N-methyl-, hydrochloride
• Nortriptyline Impurity 2 (Nortriptyline EP Impurity B)
• Cyclobenzaprine USP RC B Q: What is the storage condition of
• 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine Hydrochloride
• Einecs 207-118-3
• Cyclobenzaprine USP RC B
• Desmethyl Cyclobenzaprine Hydrochloride
• 3-(5H-Dibenzo[a,d][7]annulen-5-ylid
• Cyclobenzaprine Related CoMpound B
• Cyclobenzaprine Impurity 2(Cyclobenzaprine USP RC B)
• Cyclobenzaprine USP Related Compound B as Hydrochloride
• N-desmethyl Cyclobenzaprine HCl (USP RC B)
• Nortriptyline EP Impurity B HCl
• Cyclobenzaprine impurity 2/Cyclobenzaprine USP Related Compound B/Desmethyl Cyclobenzaprine Hydrochloride/3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine hydrochloride
• NORTRIPTYLINE EP IMPURITY B
• Cyclobenzaprine USP RC B Q: What is the CAS Number of
• Nortriptyline EP Impurity B HCl (N-Desmethyl Cyclobenzaprine HCl)
• Nortriptyline Hydrochloride Impurity B as Hydrochloride
• N-Desmethyl Cyclobenzaprine
• 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N-methylpropan-1-amine
• N-Desmethyl Cyclobenzaprine Hydrochloride
• Nortriptyline Hydrochloride EP Impurity B as Hydrochloride
• Cyclobenzaprine USP Related Compound B
• Cyclobenzaprine DesMethyl HCl
• N-Desmethylcyclobenzaprine hydrochloride solution
• N-Desmethyl Cyclobenzaprine-d3
• Cyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine (1154525)
• Cyclobenzaprine Related Compound B (10 mg) (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride)
• Cyclobenzaprine USP RC B Q: What are the applications of
• Desmethylcyclobenzaprine hydrochloride salt
• Cyclobenzaprine USP RC BQ: What is
• Cyclobenzaprine Related Compound B as Hydrochloride

N-Desmethylcyclobenzaprine Hydrochloride (Norcyclobenzaprine Hydrochloride) 1.0 mg/ml in Methanol (as free base)

CAS: 438-59-5

Cor e Forma: Single Solution

Ref: 61-AMP0079.01-01

Cyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride)

CAS: 438-59-5

Aromatic monoamines and their derivatives, salts thereof, nesoi

Fórmula: C₁₉H₁₉N·HCl

Cor e Forma: White Powder

Peso molecular: 261.15175

Ref: 45-1154525

1-Propanamine,3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-,hydrochloride (1:1)

CAS: 438-59-5

Fórmula: C₁₉H₂₀ClN

Cor e Forma: Solid

Peso molecular: 297.8218

Ref: IN-DA0037GQ

Nortriptyline EP Impurity B HCl (Cyclobenzaprine USP Related Compound B, N-Desmethyl Cyclobenzaprine HCl)

CAS: 438-59-5

Fórmula: C₁₉H₁₉N·HCl

Peso molecular: 261.37 36.46

Ref: 4Z-N-3621

3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine Hydrochloride (Norcyclobenzaprine Hydrochloride)

Produto Controlado

CAS: 438-59-5

Fórmula: C₁₉H₁₉N·ClH

Cor e Forma: Neat

Peso molecular: 297.82

Ref: 86-MM0079.01

Desmethyl Cyclobenzaprine Hydrochloride

CAS: 438-59-5

Impurity Cyclobenzaprine USP Related Compound B
Applications Desmethyl Cyclobenzaprine (Cyclobenzaprine USP Related Compound B) is a metabolite of Cyclobenzaprine.
References Wang, R.W., et al.: Drug Metab. Dispos., 24, 786 (1996),

Fórmula: C₁₉H₁₉N·ClH

Cor e Forma: Off-White

Peso molecular: 297.82

Ref: TR-D291560

Nortriptyline EP Impurity B

CAS: 438-59-5

Fórmula: C₁₉H₁₉NHCl

Peso molecular: 261.37 : 36.46

Ref: ST-EA-CP-N15002

Desmethyl cyclobenzaprine hydrochloride

CAS: 438-59-5

Desmethyl cyclobenzaprine hydrochloride is a metabolite of cyclobenzaprine, a drug used for the treatment of muscle spasms. Desmethyl cyclobenzaprine hydrochloride has been shown to have an increased potency for the termination of nerve impulses. These results were determined by in vivo studies using an assay on rat sciatic nerve and a study on human adrenergic receptors. This metabolite also shows potentiation effects with other drugs such as clonidine and prazosin, which are used to treat hypertension and anxiety, respectively. However, clinical relevance is still unknown due to the lack of data on desmethyl cyclobenzaprine hydrochloride's uptake and enhancement in humans.

Fórmula: C₁₉H₂₀ClN

Pureza: Min. 95%

Cor e Forma: White To Off-White Solid

Peso molecular: 297.82 g/mol

Ref: 3D-FD21256